Explore chapters and articles related to this topic
Bio-Based Magnetic Metal-Organic Framework Nanocomposites
Published in Anish Khan, Mohammad Jawaid, Abdullah Mohammed Ahmed Asiri, Wei Ni, Mohammed Muzibur Rahman, Metal-Organic Framework Nanocomposites, 2020
Manickam Ramesh, Mayakrishnan Muthukrishnan
Magnetic MOFs have proven potential applications as molecular magnets, magnetic molecular sensors, and in the molecular biomedicine field. The coating of the magnetic materials by biocompatible polymers, gold, activated carbon, or silica reduces the aggravated effects of the core materials and prevents it from direct exposure to the body. In the same way polymer-coated MOFs will have colloidal stability, targeting ability, augmented biocompatibility, better encapsulation efficiency, longer circulation, and leakage prevention. Heparin, poly(N-vinylpyrrolidone) (PVP), chitosan, and poly(sodium 4-styrenesulfonate)(PSS) are some of the polymer-coating derivatives for their excellent biocompatibility and aqueous solubility. Polyvinyl alcohols, phospholipids, dextran, polyethylene glycol (PEG) are few of the derivatives used for coating magnetic materials [42–44].
Wearable Nanogenerators
Published in Inamuddin, Mohd Imran Ahamed, Rajender Boddula, Tariq Altalhi, Nanogenerators, 2023
Md Mazbah Uddin, Tanvir Mahady Dip, Suraj Sharma
On the other hand, Zhang et al. developed a 2D textile substrate woven WTEG with p-type (Bi 0.5Sb1.5Te3) and n-type (Bi2Se3) yarns produced by the technique of thermal drawing (Figure 10.36(d)) (Zhang et al. 2017). Similarly, Ryan et al. developed a 2D WTEG by sewing n-type and p-type yarns onto a textile substrate (Figure 10.36(e)). Herein, the n-type yarns were fabricated by coating a PET yarn with MWCNTs and poly-N-vinylpyrrolidone (PVP). To fabric the p-type yarns, silk yarns were dyed with PEDOT: PSS. The output voltage reached 143 mV at 80 DK (Ryan et al. 2018). Table 10.10 summarizes the recently developed WTEGs built directly onto yarn substrates.
Polymeric Nanoparticles as a Vehicle for Delivery of Antioxidants in the Brain
Published in Bertrand Henri Rihn, Biomedical Application of Nanoparticles, 2017
Jean-Michel Rabanel, Ghislain Djiokeng-Paka, Charles Ramassamy
RES has also been reported as a potential antioxidant for the treatment of ischemia/reperfusion injury. A simple way to produce RES loaded NPs based on poly(N-vinylpyrrolidone)-b-poly(γ-caprolactone) polymer (PVP-b-PCL) was reported by Lu et al. In this study, PVP was used as the hydrophilic segment of the copolymer instead of PEG. The RES-loaded NPs were evaluated for the protective effect of RES on H2O2-induced oxidative stress and apoptosis in rat cortical cell coculture (containing neurons and astrocytes). RES-NPs demonstrated an enhanced neuroprotection compared to an equivalent dose of free RES (Lu et al. 2013).
Preparation of a carbon-based nanomaterial and its influence on construction engineering
Published in Journal of Experimental Nanoscience, 2023
The dispersant polyvinylpyrrolidone is dissolved in purified water and heated to 60 °C and kept at a constant temperature to completely dissolve. A water-soluble polymer known as polyvinylpyrrolidone (PVP) is generated when N-vinylpyrrolidone is synthesized. PVP is a polymer that helps to encapsulate and deliver both hydrophilic and lipophilic substances. It is non-toxic, inert, temperature-resistant, pH-stable, biocompatible, and biodegradable. High tensile strength, flexibility, and oxygen and aroma barrier properties are all characteristics of poly (vinyl alcohol). It also possesses superior film-forming, emulsifying, and adhesive qualities. The monomer N-vinylpyrrolidone6 is converted into the water-soluble polymer known as poly (vinylpyrrolidone). After that, we add the weighed and functionalized multi-walled carbon nanotubes, and put them in a magnetic stirrer to stir evenly. The mixture was sonicated for 60 min and cooled to room temperature. Then, we add an appropriate amount of defoamer to eliminate surface bubbles, then pour the dispersion into a cement mortar mixer and add a certain proportion of cement. Standard sand, water, and water reducing agent are mixed evenly and put into a standard cement glue triple mold (40 mm × 400mm × 160mm), then smoothed, vibrated, shaped, and covered with a wet cloth. After demolding after 24 h, it is moved to a standard curing box, and the test specimen was obtained after standard curing for 28 days (temperature 20 °C, humidity 95%).
PVP-microneedle array for drug delivery: mechanical insight, biodegradation, and recent advances
Published in Journal of Biomaterials Science, Polymer Edition, 2023
Keisham Nelson Mangang, Pragati Thakran, Jitu Halder, Kuldeep Singh Yadav, Goutam Ghosh, Deepak Pradhan, Goutam Rath, Vineet Kumar Rai
Polyvinylpyrrolidone (PVP) is a synthetic polymer synthesized by polymerizing N-vinylpyrrolidone monomer and Povidone. Being a biocompatible, non-toxic, inert, pH stable, non-ionic, and temperature-resistant polymer with a complex affinity toward water-soluble and water-insoluble drugs [15–17], it has been widely used for preparing MNs for local and systemic uses. It has good solubility in water and organic solvents. It is available in various grades (Table 1) and viscosities [16]. It presents good binding properties and stabilizes suspensions and emulsions [18]. After being introduced as a plasma volume expander in the 1940s [16], it has been widely used in pharmaceuticals [19,20], biomedical [17, 20], cosmetics [21], and food sectors [22]. PVP is used as a binder in many types of tablets [23] and has been recognized for internal use by the Food and Drug Association (FDA) [24]. Its unique features and chemistry facilitate the synthesis of various homopolymers, crosslinked-PVP, and copolymers with different molecular weights (MW) [17]. Despite these properties, little information is available about the mechanical insights and biodegradation potential of PVP alone or in combination.
Potentiating the solubility of BCS class II drug zaltoprofen using nanodispersion technology
Published in Journal of Dispersion Science and Technology, 2023
Selvakumar Muruganantham, Venkateshwaran Krishnaswami, Ruckmani Kandasamy, Shanmugarathinam Alagarsamy
To improve the solubility of BCS class II medications, polymers like Polyvinyl pyrrolidone K30 (PVP K30) and poloxamer 407 are used in pharmaceutical formulations. The combination of PVP K30 and Poloxamer 407 or separately have a significant solubilizing effect on these pharmaceuticals.[18] Water-soluble, nonionic PVP K30 is resistant to temperature changes, has a steady pH, and is biocompatible with a wide range of pharmaceuticals. Its molecular weight is around 40,000 g/mol and composed of N-vinylpyrrolidone monomer (Figure 1a). PVP K30 has a greater affinity for both hydrophilic as well as hydrophobic drugs. With its specific features, PVP K30 can combine with molecules with a low molecular weight, which enables the solubility enhancement and controlled release of the drug.[19–21] In addition, it has an excellent crystal inhibitory property which makes it easier to generate amorphous form dispersion after the drug is dispersed in it.[22]