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Terpenoids in Treatment of Neurodegenerative Disease
Published in Dijendra Nath Roy, Terpenoids Against Human Diseases, 2019
Linalool is a monoterpene present in the volatile oil of many aromatic plants. Pharmacological studies with linalool have demonstrated a broad spectrum of action in epileptic mouse model (Silva Brum et al., 2001). Psychopharmacological in vivo evaluation of linalool showed that this compound has dose-dependent marked sedative effects in the CNS, including anticonvulsant properties (Re et al., 2000).
Screening of antimicrobial and insecticidal properties of essential oils extracted from three Tunisian aromatic and medicinal plants
Published in International Journal of Environmental Health Research, 2023
Jihed Aouini, Olfa Bachrouch, Kamel Msaada, Nadia Fares, Selim Jallouli, Jouda Médiouni Ben Jemâa, Tarek M.A. Soliman, Jazia Sriti
The average yield obtained from EOs extracted from studied coriander is 0.29% (Table 1). Our results were similar to those reported by Sriti et al. (2009) who reported that the EO yield of Tunisian coriander was 0.30% (Sriti et al. 2009). Essential oil of coriander was characterized by a predominance of monoterpene alcohols (68.92%) (Table 1). This class is followed by monoterpene hydrocarbons and ketones (20.37% and 5.52%, respectively). Chemical composition identified 31 compounds which linalool was the major compound (64.61%) (Table 1). Similar results obtained by Kačániová et al. (2020) which found linalool (66.07%) where the major constitutes in Slovakia. Coriander EO can be considered as an important source of linalool, which is known for its biological activities and for its effectiveness against numerous bacteria such as Bacillus cereus, Pseudomonas aeruginosa, Escherichia coli and some fungal species in particular C. albicans and Aspergillus niger (Wojtunik-kulesza et al. 2019). Moreover, linalool can be used in many other fields such as flavor and fragrance in the pharmaceutical and agro-alimentary industries where it is incorporated into cosmetics such as perfume, soaps (Wojtunik-kulesza et al. 2019).
A monoterpene antioxidant, linalool, mitigates benzene-induced oxidative toxicities on hematology and liver of male rats
Published in Egyptian Journal of Basic and Applied Sciences, 2021
Olaniyi Solomon Ola, Temitope Ayooluwa Sofolahan
Benzene is a volatile aromatic hydrocarbon that can alter the microanatomy and physiology of different organs including the liver in affecting its toxicity [41]. This toxic effect is probably mediated through the generation of reactive oxygen species intermediate. Linalool is monoterpene used for medicinal purposes due to its pharmacological activities, such as sedative, analgesic, anti-inflammatory, antioxidant, antimicrobial, and antitumor properties among others [20,21]. The research investigated the protective effects of linalool against the toxicological influence of benzene on hematology and the liver of rats through the analysis of biochemical indices, basic redox status markers and assessment of genomic instability.