China 
Africa 
Explore chapters and articles related to this topic
Wound Tissue Classification with Convolutional Neural Networks
Published in Kayvan Najarian, Delaram Kahrobaei, Enrique Domínguez, Reza Soroushmehr, Artificial Intelligence in Healthcare and Medicine, 2022
Rafael M. Luque-Baena, Francisco Ortega-Zamorano, Guillermo López-García, Francisco J. Veredas
The healing of a chronic or acute wound is a complex process that constitutes one of the main problems in the field of healthcare. The main types of wounds include chronic wounds, such as pressure ulcers, diabetic foot ulcers, and arterial and venous ulcers, as well as acute wounds, such as surgical wounds, burns, etc. It has been estimated that around 451 million people in the world are affected by different types of diabetes (Cho et al. 2018) and could suffer from diabetic foot ulcers, which is one of the main diseases associated with diabetes. The global prevalence of diabetic foot ulcers has been estimated at 6.3% (Zhang et al. 2017), while it is estimated that around 15% of diabetics will develop a diabetic foot ulcer in their lifetime (Reiber 1996). On the other hand, it is estimated that 1% (Ruckley 1997; Bergqvist et al. 1999) of the population suffering from chronic venous insufficiency – which has an overall prevalence of 25–40% and 10–20% in women and men, respectively (Al Shammeri et al. 2014) – is affected by venous ulcers. In the specific case of pressure ulcers, they are responsible for a high mortality rate, close to 30%, among the older population (Landi et al. 2007). Acute and chronic wound care has a high impact on the budgets of health systems. In a recent study carried out in the United States, it has been estimated that the annual cost of wound care in that country rises in a range of between 28.1 billion dollars and 96.8 billion dollars, affecting more than eight millions of people who have suffered from these wounds (Sen 2019).
Conducting Polymer-Based Nanomaterials for Tissue Engineering
Published in Ram K. Gupta, Conducting Polymers, 2022
Murugan Prasathkumar, Chenthamara Dhrisya, Salim Anisha, Robert Becky, Subramaniam Sadhasivam
Aerogels are porous materials with attractive properties such as high specific surface area, low thermal conductivity, high pore volume, and high porosity. Their potential biomedical applications include wound care, drug delivery system, tissue engineering. Alginate, cellulose, gellan gum, and DNA have been widely used as a template for in situ polymerization with CPs. The nanoporous cellulose gels–PPy composite aerogel can provide sufficient electrical conductivity and no cytotoxic effects against nerve cells [11]. PANI aerogels are notable conductive polymeric biomaterials that have been received good attention due to their low cost, tunable morphology, redox properties, and environmental stability, but lack of strong chemical or physical interactions. The PANI cross-linked with pectin aerogel has exhibited considerable electrical conductivity, hierarchical pores, high mechanical integrity, and self-supported 3D nanoporous network structures with high surface areas [12].
Recent Advances in Pharmaceutical Applications of Natural Carbohydrate Polymer Gum Tragacanth
Published in Amit Kumar Nayak, Md Saquib Hasnain, Dilipkumar Pal, Natural Polymers for Pharmaceutical Applications, 2019
Madhusmita Dhupal, Mukesh Kumar Gupta, Dipti Ranjan Tripathy, Mohit Kumar, Dong Kee Yi, Sitansu Sekhar Nanda, Devasish Chowdhury
Advanced wound healing products contain ointments, dressing pads, bandages, wound closure tapes, hydrogels, etc., which provides a moist and occlusive environment in the complex cellular event of tissue regeneration and restoration with added antibacterial effects. GT itself reported to be non-toxic, antibacterial, and hygroscopic; interestingly when used in combinations it enhances the potentials of the wound healing process. A GT-based wound-healing product was prepared by entrapping aqueous Aloe Vera extract into the GT polymer wall. This wound care product improved human fibroblast cell growth, proliferation (98%) and migration with relative high antimicrobial activities against E. coli, S. aureus, and C. albicans (Ghayempour et al., 2016a). Further, another study has demonstrated curcumin (Cur)-loaded PCL/GT membranes, which provided the controlled release of curcumin for over 20 days, making it a potential wound care dressing patch (Ranjbar-Mohammadi et al., 2016).
Aseptic versus clean technique during wound management? Systematic review with meta-analysis
Published in International Journal of Environmental Health Research, 2023
Edward Purssell, Rose Gallagher, Dinah Gould
Traditionally wounds have been managed by utilising an aseptic or non-touch technique where only sterile contact with the wound occurs to reduce risk of infection. The National Institute for Health and Care Excellence (NICE) in the UK recommends adopting an aseptic non-touch technique for changing or removing surgical wound dressings but does not specify any particular method. NICE defines aseptic technique thus: “An aseptic technique ensures that only uncontaminated equipment and fluids come into contact with susceptible body sites. It should be used during any clinical procedure that bypasses the body’s natural defences. Using the principles of asepsis minimises the spread of organisms from one person to another” (National Institute for Health and Care Excellence 2012) (p. 24). NICE and numerous other international guideline development groups (see for example the Wound, Ostomy and Continence Nursing Society/Association for Professionals in Infection Control and Epidemiology joint statement (Wound, Ostomy and Continence Nurses Society Wound Committee and Association for Professionals in Infection Control and Epidemiology 2012)) further recommend restricting contact so that only sterile surfaces touch one another during aseptic procedures.
Acquisition of collapse temperature and the influencing factors during freeze-drying of placental decellularized matrix in freeze-drying microscopy based on image processing techniques
Published in Drying Technology, 2022
Wenya Niu, Taijie Zhan, Yaxuan Cui, Liang Chen, Mengdong Cui, Xiu Liu, Chuanbao Zang, Yi Xu
Tissue engineering materials play an important role in promoting the rapid wound healing of patients after surgery.[1,2] The human placenta due to the rich extracellular matrix,[3] the growth factors[4] such as Epidermal Growth Factor, Vascular Endothelial Growth Factor, and the excellent antibacterial properties,[5,6] and the low immunogenicity characteristics[7] make it very suitable as a raw material for preparing new wound healing tissue engineering materials. Wound dressings need to have a porous structure to facilitate gas exchange and cell adhesion.[8] And Freeze-drying technology has become a reliable method to prepare this kind of biomaterials.[9] With this technique, the placenta-derived extracellular matrix sponges can have multiple connected pores and good mechanical properties.
Design and Study of Novel Tunable ELF-PEMF System for Therapeutic Applications
Published in IETE Journal of Research, 2022
Himani Kohli, Sangeeta Srivastava, Manan Oza, Satish Chouhan, Shivani Verma, Anju Bansal, Bhuvnesh Kumar, Sanjeev Kumar Sharma
The therapeutic applications of the system can be exploited in the field of orthopedics for the treatment of non-union fractures and failed fusions. Electromagnetic field of low frequency and low field strength also act as a medical aid in various fields, such as neural regeneration, improving blood circulation, reducing depression, treatment of multiple sclerosis, orthopedic abnormalities, reduction of pain in fibromyalgia, and wound healing. Wound can be defined as a disruption of the skin surface which eventually damages the dermal layers and exposes it to various types of infection. Wounds can be classified into acute and chronic wounds according to the time of healing. Non-healing wounds as a result of ischemia, diabetes mellitus, and venous stasis are more prone to infections. Wound healing is a dynamic process which not only involves skin cell components, such as endothelial cells, keratinocytes, platelets, fibroblasts but also activates many growth factors and pathways [4]. Clinical studies done so far suggest the significant benefit of healing of diabetic foot ulcers in the PEMF-exposed group as compared to the control group [7].