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Clinical Applications of Immunoassays
Published in Richard O’Kennedy, Caroline Murphy, Immunoassays, 2017
Systemic sclerosis is a multisystem connective tissue disorder and is characterised by thickening and fibrosis of the skin (scleroderma). There are two disease patterns comprising diffuse cutaneous systemic sclerosis (dcSS) and limited cutaneous systemic sclerosis (lcSS) based on the extent of skin involvement. In dcSS, sclerotic skin is seen on the trunk and proximal limbs as well as face and distal limbs and is associated with a worse prognosis. In lcSS, scleroderma is restricted to the face, neck and limbs distal to the elbow and knee and generally has a better prognosis when compared to dcSS. Many patients with lcSS have the CREST syndrome, which is an acronym for calcinosis, Raynaud’s disease, esophageal dysmotility, sclerodactyly and telangiectasia.
Review on the current treatment status of vein of Galen malformations and future directions in research and treatment
Published in Expert Review of Medical Devices, 2021
Panagiotis Primikiris, Georgios Hadjigeorgiou, Maria Tsamopoulou, Alessandra Biondi, Christina Iosif
Gene mutations have been identified in two Mendelian autosomal dominant syndromes with incomplete penetrance and expressivity [111,112], both of which are infrequently associated with VOGMs: capillary malformation-arteriovenous malformation syndrome (RASA1) and hereditary hemorrhagic telangiectasia (ENG and ACVRL1) [110].
Varicose ulcer(C6) wound image tissue classification using multidimensional convolutional neural networks
Published in The Imaging Science Journal, 2019
V. Rajathi, R. R. Bhavani, G. Wiselin Jiji
Figure 3 shows stages of CEAP classification namely C1: Telangiectasia or reticular veins, C2: Varicose veins,C3: Oedema without skin changes, C4: skin changes to venous disease: pigmentation or eczema, C5: healed venous ulcer, C6: active venous ulcer.