Co(II) and Cu(II) coordination polymers: prevention activity on hypotension after spinal anesthesia
Published in Inorganic and Nano-Metal Chemistry, 2021
Shenyuan Zhou, Sensen Wang, Qiang Li, Shuyuan Zheng, Zhuolin Shu, Junfeng Zhang
Spinal anesthesia and epidural anesthesia have precise analgesic effects, causing muscle relaxation, and inhibit the stress response caused by surgical trauma stimulation. At the same time, it has characteristics of less physiological interference to important organs such as brain, lung, liver, and kidney and quick recovery after surgery.[1,2] It is a commonly used clinical anesthesia method. However, spinal anesthesia and epidural anesthesia have an inhibitory effect on hemodynamics. The prominent manifestation is the injection of local anesthetics into the subarachnoid or epidural space.[3] After the blocking effect occurs, it would cause blood pressure drop and hypotension, called hypotension after anesthesia. Therefore, preventing hypotension after intraspinal anesthesia is an important issue related to clinical anesthesia and patient safety.