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3D Nanoprinting in Oral Health Care Applications
Published in Ajit Behera, Tuan Anh Nguyen, Ram K. Gupta, Smart 3D Nanoprinting, 2023
Gaetano Isola, Alessandro Polizzi, Simona Santonocito
Sinus lift. Sinus position and maxillary tooth extraction may be a cause of vertical bone height reduction, which can complicate prosthetic implant treatment [77]. Sinus lift surgery can be improved through the use of grafting materials that are important to increase implant survival rates [78]. Several types of grafting materials have been used for sinus lift surgery; for example, allografts, autogenous bone, mixtures of various biomaterials, synthetics, and xenografts [79]. 3D printing and additive manufacturing make it possible to replicate the bony architecture and the graft macroporosity with minimal wastage of material. Furthermore, ethical concerns, risk of infection, and availability limits are surpassed [80]. However, the use of 3D scaffolds for sinus lift is only documented in case reports and in vivo studies, but randomized controlled clinical trials on the subject are lacking [77,81].
Haemostatic sponges as an alternative to granular bone substitute for sinus lifts
Published in Computer Methods in Biomechanics and Biomedical Engineering, 2020
S. Okley, C. Mauprivez, P. Prada, M. Dubus, F. Velard, R. Rahouadj, H. Kerdjoudj, A. Baldit
The devices were provided in a cubic shape (∼10 mm edge) by the manufacturers and were not recut. This decision was supported by the fact that the aim is to mimic their use in surgical condition. In total 5 samples per device type have been studied: 3 in dry condition, 1 in saline buffer (PBS) saturated condition and 1 for volume analysis. The dry dimensions were measured thanks to a calliper and image analysis for the volume tracking. The samples were weighed with an accurate Sartorius CPA225D scale. The device’s microstructure has been assessed through scanning electron microscopy (SEM) through two conditions: native and after 50% of applied strain. This latter load refers to the manipulation of sponges while sinus lift surgery.
Comparison of clinical efficacy of three different dentin matrix biomaterials obtained from different devices
Published in Expert Review of Medical Devices, 2023
Robert Dłucik, Bogusława Orzechowska-Wylęgała, Daniel Dłucik, Domenico Puzzolo, Giuseppe Santoro, Antonio Micali, Barbara Testagrossa, Giuseppe Acri
From the group of 70 patients, 37 had titanium implants inserted into bone augmented by DM and 33 underwent only augmentation procedures by the DM. The total number of implants, all placed with an average torque force of 35 Ncm, was 84, and in particular 51 in patients of the BonMaker group, 22 in the Tooth Transformer group, and 11 in Smart Dentin Grinder group. From the BonMaker group, 15 patients had implants placed immediately after extraction together with bone augmentation by the DDM; in addition, three block-type surgeries with immediate implant loading in esthetic area were performed in the patients from this group. In the Tooth Transformer group, four patients had implants immediately loaded into the bone alongside with augmentation by the DDM. In the Smart Dentin Grinder group, three sinus lift procedures were performed, from which one patient had sinus lift with immediate implant insertion into the bone augmented by a mineralized dentin matrix (MDM). In this study, measurements were acquired via CBCT scans before tooth extractions, after surgery and 3–4 months later to evaluate the outcomes. Microbiological testing of samples coming from all three devices has been performed. Results were negative for all samples. In addition, four impacted upper third molars were extracted from four random patients (one tooth from each patient). Three samples, one for each device, were prepared, following manufacturer’s instruction for sample preparation. The fourth tooth had soft tissues removed and was used as a control sample. Secondly, the tooth was placed in 3% hydrogen peroxide for preliminary disinfection, and then into a sterile saline solution in a plastic container. All four samples were sent to the University of Messina, Messina, Italy.