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Use of Artificial Intelligence in Sepsis Detection and Management
Published in Sandeep Reddy, Artificial Intelligence, 2020
In the United States, 750,000 people are diagnosed with sepsis every year (Bansal et al., 2018), accounting for 250,000 deaths (Harrison et al., 2015) and 51% of total ICU admissions (Bansal et al., 2018). Sepsis is a complex disease with an even more complex management and treatment process. Diagnosis of sepsis consists of suspected or proven infection and systemic inflammatory response syndrome (SIRS). Delay in diagnosis places a burden on the healthcare system, costing close to 15.4 billion dollars annually (Bansal et al., 2018). Advanced detection can help mitigate these challenges by allowing for earlier diagnosis (Harrison et al., 2015). Furthermore, initiating early treatment would have a significant impact on mortality rates and alleviate the strain on healthcare resources allocated to sepsis treatment (Bansal et al., 2018).
Relationship between Procalcitonin (PCT) and High-Density Lipoprotein (HDL) in bacterial sepsis
Published in Cut Adeya Adella, Stem Cell Oncology, 2018
D. Tarigan, T. Kembaren, A. Rahimi
Sepsis is defined as an infection (whether a suspicion or evidence) accompanied by a systemic inflammatory response/SIRS (Systemic Inflammatory Response Syndrome). This condition originates from the interaction between pathogenic microorganisms and the immune system that triggers an excessive and irregular inflammatory response that is destructive. The new marker of sepsis, procalcitonin (PCT), has better accuracy values than previous markers (Wyllie et al., 2005), but is limited by relatively high prices and not all health facilities can afford it. Therefore it is necessary to find a marker that can predict sepsis and is also simple, cheap and easy to use in everyday practice without any additional cost (Wyllie et al., 2005; Christ dan Muller, 2005).
Effect of ambient temperature on daily hospital admissions for acute pancreatitis in Nanchang, China: A time-series analysis
Published in International Journal of Environmental Health Research, 2022
Bozhen Li, Wenzhong Huang, Pengguo Chen, Jianyong Chen, Ivano Biviano, Zhaohan Wang
Acute pancreatitis (AP) is an acute inflammation of the pancreas, which is often closely related to bile duct obstructive obstruction, chronic alcoholism, vascular factors, pancreatic trauma and infection. The AP can lead to localized injury, systemic inflammatory response syndrome and organ failure, with a high death rate, high treatment costs and causing great pain and financial burden to patients (Petrov and Yadav 2019). As a common medical emergency, the annual incidence of AP is in the range of 12.4–67.1 per 100,000 people per year (Eland and Sturkenboom 2000; Sepanlou et al. 2020), and an increasing trend with a rate of more than 3.9% annually has been observed (Lindkvist et al. 2004; Lankisch et al. 2008). Because AP may be easily determined using case history (e.g. gallstones, alcohol consumption, hypertriglyceridemia, pregnancy, surgery, drugs and trauma) this is used for an immediate diagnosis of acute pancreatitis on admission (Lankisch et al. 1996; Pu et al. 2020).