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A comprehensive summary of disease variants implicated in metal allergy
Published in Journal of Toxicology and Environmental Health, Part B, 2022
Ka Roach, Jr Roberts
Allergic rhinitis is an allergic response of the nasal mucosa that occurs in 10–30% of the general population (Pawankar et al. 2013). The disease is characterized by the presence of immediate onset nasal congestion and itching, sneezing, and rhinorrhea following exposure to aeroallergens present in the air (Bousquet et al. 2020). Allergen-specific IgE molecules are responsible for the clinical manifestations of the disease, and similarly, allergic rhinitis often presents concurrently with asthma in many individuals; however, many individuals afflicted with rhinitis do not exhibit concomitant asthmatic responses. Other co-morbidities commonly implicated in cases of allergic rhinitis include allergic conjunctivitis, rhinosinusitis, and atopic dermatitis (Pawankar et al. 2013).