Precursor cells

Precursor cells

A precursor cell is a lineage-restricted cell that is not fully differentiated and is responsible for producing mature cells in tissue development and regeneration processes. It includes stem cells and progenitor cells and is a vital component in the production of various cell types, including neurons, astrocytes, oligodendrocytes, microglia, endothelial cells, oligodendrocyte precursor cells (NG2 cells), ependymal cells, smooth muscle cells, and pericytes in the brain.From: Tissue Engineering [2019], Encyclopedia of Biomaterials and Biomedical Engineering [2019], Scaffolding In Tissue Engineering [2019], Toxic and carcinogenic effects of hexavalent chromium in mammalian cells in vivo and in vitro: a recent update [2022]

Tissue engineering and regenerative medicine

View Chapter

Purchase Book

Published in Ronald L. Fournier, Basic Transport Phenomena in Biomedical Engineering, 2017

Ronald L. Fournier

Stem cells have the potential of being a rich source of cellular material for TERM applications, and there is much interest in the use of both adult and embryonic stem cells. Adult stem cells are found within a variety of tissues in the adult body, and they are the precursor cells that are needed for repairing or rebuilding tissue as a result of injury, disease, or aging (Pittenger et al., 1999).

Genetic variants affecting chemical mediated skin immunotoxicity

View Article

Journal Information

Published in Journal of Toxicology and Environmental Health, Part B, 2022

Isisdoris Rodrigues de Souza, Patrícia Savio de Araujo-Souza, Daniela Morais Leme

Innate lymphoid cells (ILCs) are immune cells present on the skin surface and derived from a hematopoietic stem cell-derived common lymphoid precursor cell in the bone marrow. Although, alternative sites of development exist, such as secondary lymphoid organs (Kim 2015; Rafei-Shamsabadi et al. 2019). These cells possess multiple subsets – traditionally classified as ILC1, ILC2 or ILC3- that present different functions depending upon their transcription factor expression profile and/or expression of effector cytokines, promoting either tissue homeostasis or detrimental inflammatory processes at epithelial barrier surfaces and skin disease such as AD and psoriasis (Bielecki et al. 2021; Kim 2015; Rafei-Shamsabadi et al. 2019).

Explore chapters and articles related to this topic

Tissue engineering and regenerative medicine

Genetic variants affecting chemical mediated skin immunotoxicity