China
Africa
Explore chapters and articles related to this topic
Materials in Additive Manufacturing
Published in G.K. Awari, C.S. Thorat, Vishwjeet Ambade, D.P. Kothari, Additive Manufacturing and 3D Printing Technology, 2021
G.K. Awari, C.S. Thorat, Vishwjeet Ambade, D.P. Kothari
3D printing implemented in the medical sector has been available for a number of years through various applications. Organ transplantation has difficulties and 3D tissue engineering-based jet printing offers a possible solution. Some research defines organ printing as a fast prototyping computer-aided 3D-printing technology based on the use of layer-by-layer deposition of cell and/or cell aggregates into a 3D gel with sequential maturation of the printed structure into perfumed and vascularized living tissue or organ. Bio-printing is a desirable way to create tissues and organs in hospitals. Successful implantation depends on compatible materials. A variety of biomaterials can be found, such as curable synthetic polymers, synthetic gels, and naturally derived hydrogels. Prosthetics is the first biomedical field to use 3D printing and presents a number of achievements. We can quote a patient’s skull anatomy reproduced by 3D printing for pre-surgical use in manual implant design and production, and by enhancing the stability of the fixation of the custom-made total hip prosthesis and restoring the original biomechanical characteristics of the joint. Several applications combine some compostable or allergenic scaffolding with cellular bio-printing to create personalized biologic prosthetics that have the potential to act as a transplantable replacement tissue. New articles have shown that the medical 3D printing market could reach $983.2 million by 2020.
On the Disruptive Potential of 3D Printing
Published in Diana M. Bowman, Elen Stokes, Arie Rip, Embedding New Technologies into Society, 2017
Pierre Delvenne, Lara Vigneron
Anyhow, the day when 3D bioprinted human organs are readily available is probably drawing closer. However, major challenges will need to be overcome in the first place. The barriers to full-organ printing are not just technical (this is expected to be very difficult to print blood vessels or vascular tissues); they are also economic and regulatory. The first organ- printing machine will cost hundreds of millions of dollars to develop, test, produce and market. Crucially, bioprinting tissues or organs for human consumption will probably involve lots of regulatory testing before any products can be brought to market. In the very near future, according to Gartner Group, bioprinting is expected to cause a global debate about regulating the technology or banning it for both human and nonhuman use [21]. If bioprinting is the way forward to safer drugs, pharmaceutical industry will have to provide the regulatory agencies, such as, for example, the American Food and Drug Administration and the European Medicines Agency, with sufficient evidence on the safety of such drugs when tested on 3D printed tissues.
Organ Printing and Cell Encapsulation
Published in Claudio Migliaresi, Antonella Motta, Scaffolds for Tissue Engineering, 2014
Savas Tasoglu, Umut Atakan Gurkan, Sinan Guven, Utkan Demircia
Current engineered 3D tissues are designed to culture cells within natural or synthetic scaffolds.11-15 These engineered scaffolds function as a 3D structure on which cells grow, interact with the ECM, and communicate with other cells in their proximity.14-16 Printing biocompatible hydrogels accompanying cells and biologically active molecules with high precision is an emerging strategy in tissue engineering.1718 Organ printing can be defined as biofabrication of 3D living human organs from raw materials including cells, extracellular matrices, nutrients, therapeutic drugs, growth factors, and other biomaterials. Computer-aided design of a target organ/ tissue is initially developed to generate the blueprint that enables the robotic bio-dispenser to print the designed structure layer-by-layer. Bioprinting techniques enable researchers to generate geometrically well-defined scaffolds using polymers or blends of polymers and other cell inductive particles (e.g., hydroxy apatite) providing support and stimulation for seeded cells.17-19 Tissue engineering scaffolds are expected to enhance and promote cell adhesion, proliferation, extracellular matrix (ECM) production, and cell motility. Bioprinting offers scalable and automated fabrication of tissue engineered products.
A review of wound dressing materials and its fabrication methods: emphasis on three-dimensional printed dressings
Published in Journal of Medical Engineering & Technology, 2022
S. Pravin Kumar, Yuvasri Asokan, Keerthana Balamurugan, B. Harsha
3D bioprinting is a relatively new technique widely used in tissue engineering for organ printing and engineering scaffolds. Here, organs, scaffolds, bones, etc can be printed using cell-laden bio-inks. Extremely thin layers of scaffolds can be printed using this technique. The natural polymers used in bioprinting can imitate the human extracellular matrix, which is crucial for wound healing. However, the bio-inks developed for printing should have the required rheological properties [102] in order to be successfully printed, which can be quite demanding because of hardware requirements, compared to the normal 3D printing. Nevertheless, both 3D printing and 3D bioprinting can provide scaffolds with the above-mentioned properties. Different techniques used in 3D printing of scaffolds are detailed as follows:
Smart materials in additive manufacturing: state of the art and trends
Published in Virtual and Physical Prototyping, 2019
Some research defines organ printing as a rapid prototyping computer-aided 3D printing technology, based on using a layer by layer deposition of cell and/or cell aggregates into a 3D gel with a sequential maturation of the printed construct into perfused and vascularised living tissue or organ (Mironov et al. 2003). Bioprinting is an attractive method to create tissues and organs at hospitals. The success of an implantation depends on compatible materials. Prosthetic is the first biomedical area that used 3D printing and it presents several successes. Several applications combine some degradable or allogeneic scaffolding with cellular bioprinting to create customised biologic prosthetics that have the great potential to serve as transplantable replacement tissue (Giovinco et al. 2012; Mannoor et al. 2013; Xu et al. 2013). Metamaterials and lattices are developed to fabricate open-porous cellular structures in 3D Printing (Compton and Lewis 2014).