China
Africa
Explore chapters and articles related to this topic
Nanoemulsions in Non-Invasive Drug Delivery Systems
Published in Bhaskar Mazumder, Subhabrata Ray, Paulami Pal, Yashwant Pathak, Nanotechnology, 2019
Ratna Jyoti Das, Subhabrata Ray, Paulami Pal, Anup Kumar Das, Bhaskar Mazumder
Nail psoriasis and fungal infections are very common among patients, particularly those who are immune compromised. Nail diseases are generally treated by the administration of huge doses of drugs orally over a prolonged duration. Oral therapy is mainly associated with various adverse effects. However, the impermeability of the nail plate lowered the amount of drug entry from topical products into the deeper tissues of the nail, hence, topical therapy was poorly successful as a monotherapy. There is an immediate need for the development of technologies for the improvement of the topical delivery of drugs via and across the nail to improve its positive influence and to minimize the recurrence of nail disorders. The use of chemical nail permeability enhancers and biophysical technologies, such as iontophoresis and sonophoresis, have been investigated as potential approaches to improve drug delivery into the nail bed. The topical delivery of different drug formulations as nail lacquers, creams, lotions, and gels are hindered by the low penetration into the human nail plates and there is a need for repeated dosing for a longer period of time for effective treatment. This is where the potential of nanoemulsions as delivery vehicles for transungual delivery comes into focus.
Color and Texture Prior Based Segmentation and Analysis of Psoriatic Disease Types Using MPSO
Published in IETE Journal of Research, 2021
The severity of nail psoriasis has been analyzed [11] as a predictor for a more severe disease course using the ChildCAPTURE registry. The study [12] established an accurate and objective psoriasis assessment method based on segmenting images by the machine learning technology. The Caucasian patient’s standardized photographs were assessed, and typical psoriatic lesions were labeled.