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Ferritin levels after ferrous fumarate supplementation in the 2nd trimester of pregnancy
Published in Cut Adeya Adella, Stem Cell Oncology, 2018
Other examinations to prove the occurrence of iron deficiency include red blood cells, iron serum, total iron binding capacity serum, serum transferrin saturation, transferrin serum levels and ferritin serum levels. Microcytosis is a sensitive iron deficiency index whose value is limited by the physiologic increase in Mean Corpuscular Volume (MCV) that often occurs during pregnancy.
Occurrence and Importance of Heavy Metal Contamination
Published in Jiaping Paul Chen, Decontamination of Heavy Metals, 2012
Iron (Fe) is the most abundant transition element. It is essential in the oxygen-carrying protein molecule of blood. The symptoms of iron deficiency include fatigue and shortness of breath. Generally speaking, it is well represented in our food sources such as beef, fish, poultry, egg yolk, oysters, and enriched cereals and breads. The RDA of iron is 18 mg/day.
Iron-Siderophore and Tumorigenesis
Published in Debasis Bagchi, Manashi Bagchi, Metal Toxicology Handbook, 2020
Sayantan Maitra, Dibyendu Dutta
Iron deficiency is defined as the state when there are no mobilizable iron stores and in which there is a compromised supply of iron to tissues. This unavailability of iron leads to the occurrence of anemia, a condition in which the number of red blood cells (RBCs) in blood is low or blood cells have lower than normal level of hemoglobin [1].
Two new coordination polymers containing 1,4-bis(2-ethylbenzimidazole) as luminescent chemosensors for Fe3+ ions and tetracycline
Published in Journal of Coordination Chemistry, 2023
Jia-Ning Cui, Li-Juan Liu, Qing-Lin Cao, Gui-Ying Dong
Iron is mostly dispersed in red blood cells and is the most plentiful transition metal in the human body, with an average total mass between 4.2 and 6.1 g [9, 10]. It plays an important role in the transportation and exchange of O2 in the blood. It is also present in a variety of essential enzymes and is critical for cell metabolism pathways [11]. Iron and immune function are closely related; sufficient iron is necessary to maintain normal function of the immune system, and anomalous iron levels can lead to adverse reactions and diseases [12]. Iron deficiency in the human body will lead to changes in the blood system, immune system, digestive system, etc., causing fatigue, memory loss, indigestion, palpitation, shortness of breath, and severe anemia heart disease [13]. Fe3+ is indispensable in the human body and plays a crucial role in pathological and physiological developments such as oxygen metabolism, oxygen absorption, and enzymatic catalysis [8, 14].
Ascorbate exacerbates iron toxicity on intestinal barrier function against Salmonella infection
Published in Journal of Environmental Science and Health, Part C, 2022
Tengjiao Guo, Yisheng Yang, Jiayou Zhang, Yu Miao, Feifei Lin, Suqin Zhu, Caili Zhang, Haohao Wu
Iron is an essential trace metal in human nutrition, and constitutes an important component of oxygen transport proteins (i.e. hemoglobin and myoglobin) and heme/non-heme iron-containing enzymes. Iron deficiency is a public nutritional matter around the world, and is the predominant cause of anemia, a condition affecting an estimated 27% of the population worldwide.1 Iron deficiency can be caused by insufficient dietary iron intake, iron malabsorption due to inflammatory or renal diseases, and active iron demand during pregnancy or children’s growth, and it adversely impacts cognitive development, immunity and work performance.2 Iron supplementation and fortification are cost-effective practical approaches to combat iron deficiency, but have been associated with increased risk of infectious diseases (e.g. diarrhea and malaria).3
Iron balance and iron supplementation for the female athlete: A practical approach
Published in European Journal of Sport Science, 2018
Charles R Pedlar, Carlo Brugnara, Georgie Bruinvels, Richard Burden
Symptoms of fatigue indicate potential iron deficiency. The gold standard for measuring iron stores is a bone marrow biopsy, but since this is not practical in athletes, and the interpretation of this test is plagued by a wide variability (Stancu et al., 2010) we recommend alternative methods based on blood testing. Serum ferritin (sFer) has been used as a biomarker of iron stores since a direct correlation between plasma ferritin and whole body iron was established in the 1970s (Jacobs & Worwood, 1975). Periodic screening sFer and [Hb] is recommended for all athletes by the International Olympic Committee (Ljungqvist et al., 2009).