Hypodermic needles – Knowledge and References

Explore chapters and articles related to this topic

The Challenge of Human Skin

Published in George K. Knopf, Amarjeet S. Bassi, Smart Biosensor Technology, 2018

Puneet Khanna, Steven Hoath, Rod Smallwood, Shekhar Bhansali

In typical clinical and biomedical applications, drug injection or biofluid sampling is done using hypodermic needles. Though utilitarian, this method causes undesirable pain and excessive tissue trauma. This is particularly troublesome when frequent administration of drugs is necessary (such as administration of insulin). Furthermore, control of drug delivery is highly approximate using macroneedles.

Finite element analysis and optimization of microneedle arrays for transdermal vaccine delivery: comparison of coated and dissolving microneedles

View Article

Journal Information

Published in Computer Methods in Biomechanics and Biomedical Engineering, 2023

Noppamas Yolai, Pikkanet Suttirat, Jeerapond Leelawattanachai, Chaiwoot Boonyasiriwat, Charin Modchang

Vaccines are traditionally administered using a hypodermic needle. Although the hypodermic needle-based vaccination is commonly used in clinical practices, it might pose a challenge in resource-limited settings as it requires trained personnel. The injection also causes pain and induces hypersensitivity, such as bleeding at the site of administration or risk of contamination (Kim et al. 2012; Ita 2015). Owing to these difficulties, microneedle arrays have recently been proposed as an alternative device for delivering vaccines into the skin.