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Japanese Regulations and Standards for Medical and Dental Grade Gloves
Published in Robert N. Phalen, Howard I. Maibach, Protective Gloves for Occupational Use, 2023
K. Matsunaga, T. Ohhara, A. Takeuchi, R. Nakaoka, Y. Haishima
The definitive diagnosis of LA is based on clinical symptoms and a prick test using NRL rubber glove extracts. Hevein b 6.02 is the main antigen of NRL gloves, and the Hev b 6.02-specific IgE antibody test, which has been covered by insurance since 2016, is now a useful test for LA diagnosis.39 Hevein is included in class I chitinases of chestnut, avocado, and banana and is the responsible antigen that cross-reacts with these fruits and causes latex-fruit syndromes.40
Natural latex serum: characterization and biocompatibility assessment using Galleria mellonella as an alternative in vivo model
Published in Journal of Biomaterials Science, Polymer Edition, 2022
Giovana Sant’Ana Pegorin Brasil, Patrícia Pimentel de Barros, Matheus Carlos Romeiro Miranda, Natan Roberto de Barros, Juliana Campos Junqueira, Alejandro Gomez, Rondinelli Donizetti Herculano, Ricardo José de Mendonça
Some studies have shown that active proteins identified in NRL may constitute a conglomerate of growth factors, considering that LPP has been demonstrated to improve local vascularization, induce the angiogenesis and stimulate epithelization [23, 31, 46]. Furthermore, it was demonstrated that whole latex presented antifungal activity against a broad spectrum of potential plant fungal pathogens. It was also seen that NLS has antimicrobial activity against Candida spp. due to the presence of hevein, a small cysteine-rich protein, which has strong antimicrobial activity [51], in addition to presenting antifungal activity against Aspergillus niger [50, 52].
Gentamicin encapsulated within a biopolymer for the treatment of Staphylococcus aureus and Escherichia coli infected skin ulcers
Published in Journal of Biomaterials Science, Polymer Edition, 2021
José Lúcio Pádua Gemeinder, Natan Roberto de Barros, Giovana Sant’Ana Pegorin, Junya de Lacorte Singulani, Felipe Azevedo Borges, Marina Constante Gabriel Del Arco, Maria José Soares Mendes Giannini, Ana Marisa Fusco Almeida, Sérgio Luiz de Souza Salvador, Rondinelli Donizetti Herculano
It was observed that the NRL biomembrane (12.40 ± 0.90 mm) presented a growth inhibition halo against S. aureus. In previous studies, NRL has demonstrated antimicrobial activity against Candida spp. and other pathogens due to the presence of hevein, a small cysteine-rich protein, which have strong antimicrobial activity [63]. On the other hand, the NRL biomembrane (0.00 ± 0.00 mm) did not inhibited E. coli growth.