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Biological Applications of Diamond
Published in James C Sung, Jianping Lin, Diamond Nanotechnology, 2019
Catheter ablation is an invasive treatment method for cardiac arrhythmia by thermal destruction of the structures causing arrhythmia. Figure 8.11 shows the sketch of conventional ablation catheter setup and the temperature sensor.13 To improve the accurate measurement and controllability of the temperature so as to control the size of the lesion, Müller and coworkers designed a diamond-based heater system shown in Fig. 8.12.13Figure 8.13shows that the diamond heater causes nearly perfect circular lesions with homogeneous depths to the tissue, whereas the conventional catheter (radio frequency (RF) catheter) results in large lesions, which are difficult to control.
Ablation therapy
Published in Riadh Habash, BioElectroMagnetics, 2020
McRury and Haines [67] discussed the role of electrical ablation, especially RFA, as a treatment for SVTs and reviewed the engineering principles and biological responses to ablation. The authors stated that RF catheter ablation is a successful technique in clinical arrhythmia management, with reported success rates of greater than 95% in many series. The indications for clinical RF catheter ablation continue to broaden.
The WATCHMAN left atrial appendage closure device for patients with atrial fibrillation: current status and future perspectives
Published in Expert Review of Medical Devices, 2020
Lisette I.S. Wintgens, Moniek Maarse, Martin J. Swaans, Benno J.W.M. Rensing, Vincent F. Van Dijk, Lucas V.A. Boersma
Although catheter ablation (CA) has emerged as a safe and effective treatment for AF and has a class I recommendation supported with level A evidence in ESC guidelines, success rates are variable from 30% to 75% depending on type of AF and comorbidities. Long-term success rates at 5 years may even decrease further, especially for non-paroxysmal forms of AF. So far, no RCTs have shown a significant reduction of thromboembolic events after CA. Therefore, guidelines recommend indefinite continuation of OAC following CA in patients at high risk for stroke, regardless of short-term outcome. In patients that undergo LA CA, concomitant LAAC device implantation may be considered to avoid lifelong continuation of anticoagulation. Combining CA and LAAC in one single procedure may provide a straightforward strategy aiming at concomitant rhythm control as well as stroke prevention. In a number of multicenter registries, the combined CA and LAAC procedure has been shown a valuable and practical approach with low rates of periprocedural complications and greatly reduced stroke and bleeding rates [40–44].