5S rRNA – Knowledge and References

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Glossary of scientific and technical terms in bioengineering and biological engineering

Published in Megh R. Goyal, Scientific and Technical Terms in Bioengineering and Biological Engineering, 2018

rRNA (ribosomal RNA) refers to the RNA molecules, which are essential structural and functional components of ribosomes, the organelles responsible for protein synthesis. The different rRNA molecules are known by their sedimentation (Svedberg; symbol S) values. E. coli ribosomes contain one 16S rRNA molecule (1541 nucleotides long) in the same (small) sub-unit and a 23S rRNA (2904 nucleotides) and a 5S rRNA (120 nucleotides) in the large sub-unit. These three rRNA molecules are synthesized as part of a large precursor molecule which also contains the sequences of a number of tRNAs. Special processing enzymes cleave this large precursor to generate the functional moieties.

An insight on the advancements of biological technologies in the bioremediation of textile effluents

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Journal Information

Published in Urban Water Journal, 2022

Swarnkumar Reddy, Jabez Osborne

Metagenomics was first introduced and practiced by Handelsman in 1998 in their report on biochemical diversity of soil microbes; however, earlier report on metagenomic was proposed by Pace et al. in 1985. They reported the metagenomic sequencing of ribosomal RNA with the existing 5S rRNA sequences. The phylogenetic affinities of organisms contributing to the analyzed 5S rRNAs were defined in the first approach. This was is followed by analyzing the mixed populations using 16S rRNA genes with shotgun-cloned using total DNA isolated from mixed microbial populations.