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Molecular Diagnosis of Endometrial Receptivity
Published in Carlos Simón, Carmen Rubio, Handbook of Genetic Diagnostic Technologies in Reproductive Medicine, 2022
Maria Ruiz-Alonso, Diana Valbuena, Carlos Simón
Endometriosis is an estrogen-dependent disorder affecting an estimated 10% of women of reproductive age [51], and its prevalence in women experiencing pain or infertility can be as high as 50% [52]. Endometriosis is defined by the presence of endometrial tissue outside the uterus; symptoms may range from practically none to chronic pelvic pain, dysmenorrhea, and cyclic urinary or bowel complaints. It has an impact on women's physical, mental, and social well-being and is commonly believed to relate to infertility.
Manual or Hand Morcellation in Minimally Invasive Surgery
Published in John C. Petrozza, Uterine Fibroids, 2020
Janelle K. Moulder, Tarek Toubia, Michelle Louie
Specimen morcellation can create diagnostic challenges for pathologists. Identification of endometrial tissue among numerous fragments of non-oriented tissue is difficult [31]. Even if the endometrium is identified, a malignancy could be missed and staging may be impossible [32]. Compared to electromechanical morcellation, hand morcellation has the potential to maintain more normal uterine architecture to help attain a correct diagnosis [32]. Staining the endometrium with methylene blue dye [33] or trypan blue dye [31] also facilitates identification and orientation of the endometrium.
Uterine Cavity Assessment (Saline Hysterosonography)
Published in Arianna D'Angelo, Nazar N. Amso, Ultrasound in Assisted Reproduction and Early Pregnancy, 2020
Endometrial hyperplasia is characterized by irregular, thickened, glandular, or heterogeneous endometrium with or without abnormal uterine bleeding. The ultrasonographic diagnosis is confirmed by histologic examination of an endometrial tissue sample. Saline hysterosonography has a diagnostic accuracy of 100%, as observed by Soares and colleagues [29].
Endometriosis-associated cancer
Published in Climacteric, 2021
The association between endometriosis and cancer has been studied for a number of years. Endometriosis is a disease in which endometrial tissue develops outside the original uterine cavity for which a number of etiological factors have been ascribed. Over the last few decades, significant data have accumulated to support the thought that some gynecologic cancers originate from endometriosis. Sampson first published a report in 1927 alluding to malignancy associated with endometriosis, wherein he described specific criteria for endometriosis-associated ovarian cancers [1]. His original criteria included the following:Endometriosis in association or in close proximity to the cancer.No other primary tumor site must exist.Histology of the tumor must be consistent with an endometrial origin.
Growing on (in)fertile ground: an evolutionary concept analysis of Black female fertility
Published in Human Fertility, 2021
Morine Cebert, Rosa Gonzalez-Guarda, Eleanor Stevenson
Endometriosis is a condition where endometrial tissue is found outside of the pelvic cavity and adheres to abdominal organs (Duffy et al., 2014). It is experienced by 3–6% in women aged between 15 and 44 years old and is a known contributor to pelvic pain, dysmenorrhea, dyspareunia and infertility. Treatment of endometriosis is often with oral contraceptives or surgical management. Despite Black women experiencing the lowest incidence of endometriosis (Cramer & Missmer, 2002; Missmer et al., 2004), endometriosis was found to be one of the top diagnoses that led Black women to undergo gynaecological surgery (Kyama et al., 2004). The literature suggests there are broader health disparities with regard to the experiences of women with endometriosis as opposed to other ethnic groups.
The effects of endometrioma size and bilaterality on ovarian reserve
Published in Journal of Obstetrics and Gynaecology, 2020
Cihan Karadağ, Tevfik Yoldemir, Sinem Demircan Karadağ, Abdulkadir Turgut
Endometriosis is defined as the presence of endometrial tissue outside the uterus and is associated with pelvic pain and infertility (Kennedy et al. 2005). The prevalence of endometriosis even rises up to 30% to 50% in patients with infertility and pelvic pain (Rogers et al. 2009). Endometriomas (OMAs) are present in 20–40% of women with endometriosis (Vercellini et al. 2003). There is a relationship between OMAs and infertility, and it is now generally accepted that endometriosis lowers fecundity. Although, the mechanism is still unclear, studies have shown that OMAs negatively affect the rate of spontaneous ovulation, as well as reducing the amount of follicular number and activity in the adjacent ovarian tissue (Benaglia et al. 2009). Management options of OMAs include expectant management with serial imaging, medical treatment, surgical removal, and in vitro fertilisation (IVF) if related with infertility (PAIN 2014).