China
Africa
Explore chapters and articles related to this topic
Stroke
Published in Henry J. Woodford, Essential Geriatrics, 2022
The ECASS III trial randomised 821 people (mean age 65) and found that thrombolysis was effective between 3 and 4.5 hours from stroke onset.25 A favourable outcome (not dead or severely disabled (modified Rankin Score < 2 [mRS – see appendix A]) was found in 52% of the treatment group compared to 45% of the controls (OR 1.34; 95% CI 1.02–1.76; NNT = 14). SICH occurred in 2.4% with rt-PA and 0.3% with placebo. This trial excluded people aged over 80.
Blood Pressure Control in Acute Stroke
Published in Stephen M. Cohn, Alan Lisbon, Stephen Heard, 50 Landmark Papers, 2021
Within 24 hours of randomization, mean SBP in the intervention group was reduced by 12.7%, whereas SBP decreased by 7.2% in the control group. The endpoint of death and disability (modified Rankin Scale) did not differ between the two groups at 14 days or hospital discharge or at the 3-month follow-up.
Stroke and Transient Ischemic Attacks of the Brain and Eye
Published in Philip B. Gorelick, Fernando D. Testai, Graeme J. Hankey, Joanna M. Wardlaw, Hankey's Clinical Neurology, 2020
The severity of the stroke also can be assessed by the modified Rankin Scale score (mRS), which quantifies disability, and to some extent, handicap (Table 12.15). Other scores of disability and handicap include the Barthel Index, Functional Independence Measure (FIM), Stroke Impact Scale (SIS), and Short Form (SF)-36.
Circadian preference and stroke characteristics: A descriptive study
Published in Chronobiology International, 2022
Eveli Truksinas, Cristina Frange, Giuliano da Paz, Eliana Lottenberg Vago, Monica Levy Andersen, Sergio Tufik, Fernando Morgadinho Santos Coelho
The Morningness-Eveningness Questionnaire (MEQ) was used to establish circadian preference, with scores ≤41 indicating evening types; ≥59 indicating morning types; and scores between 42–58 indicating intermediate types (Benedito-Silva et al. 1990; Horne and Ostberg 1976). As we used a self-report questionnaire, we use the term circadian preference (CP) rather than chronotype. The modified Rankin scale (mRS) was used to determine the degree of disability or dependence in the daily activities of the participants. The scale runs from 0 to 6, with 0 describing participants without symptoms; grade 1, participants without significant disability despite symptoms; grade 2, slight disability; grade 3, moderate disability; grade 4, moderately severe disability; grade 5, severe disability and grade 6, death (Wilson et al. 2002). After matching, the results of the MEQ questionnaires, comorbidities, age, gender, and the results of a full-night polysomnography (PSG) examination were gathered for the control group.
Clinical factors associated with trunk control after stroke: A prospective study
Published in Topics in Stroke Rehabilitation, 2021
Laís Geronutti Martins, Rafael Dalle Molle da Costa, Lorena Cristina Alvarez Sartor, Juli Thomaz de Souza, Fernanda Cristina Winckler, Taís Regina da Silva, Gabriel Pinheiro Modolo, Hélio Rubens De Carvalho Nunes, Silméia Garcia Zanati Bazan, Luis Cuadrado Martin, Gustavo José Luvizutto, Rodrigo Bazan
Participants with lower modified Rankin scale scores at hospital discharge in this study presented satisfactory trunk control at 90 days. In this study, it was also established that the cutoff point for predicting worse trunk control was an mRS score of ≥3 at hospital discharge. The modified Rankin Scale is the most widely used outcome measure in stroke trials and is strongly associated with global deficiency (in particular, physical deficiency) and with the necessity for assistance after a stroke, given that its score is highly associated with participants’ ability to perform basic and instrumental activities of daily life.35 The higher the Rankin score is, the worse the functional capacity, indicating that the patient needs assistance in most activities of daily living, which is reflected in participants with poor trunk control.36
Dosage and predictors of arm practice during inpatient stroke rehabilitation: an inception cohort study
Published in Disability and Rehabilitation, 2021
Angela Vratsistas-Curto, Catherine Sherrington, Annie McCluskey
Participants were recruited between October 2011 and January 2013. Figure 1 shows the flow of participants through the study. A total of 905 people were screened with all 74 people assessed as being eligible consenting for the study. A further 26 people were excluded due to cognitive or communication impairment but were still eligible for collection of usual care data, giving a total of 100 participants. A single influential outlier was identified and removed from the sample leaving 99 participants in the analysis (10.9% of people screened). Characteristics of the included participants on admission to the stroke unit are presented in Table 1. Supplementary Table S1 provides demographic data on the full sample prior to removal of the influential outlier. The average age of the 99 participants (including those with cognitive impairment) was 75.8 years (standard deviation (SD)=12.4). The median modified Rankin Scale score on admission indicates a moderately severe level of disability. Length of stay on the unit varied, with a range from 4 to 124 days, and an average of 36.9 days (SD = 30.0, median = 28.0, IQR = 39.5).