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Antiasthma Agents during Pregnancy
Published in “Bert” Bertis Britt Little, Drugs and Pregnancy, 2022
Most medical treatments for asthma are safe during pregnancy. The first-line treatments include antihistamines, decongestants, and intranasal glucocorticoids. The clinical goals of asthma treatment are to: (1) control or decrease the frequency and number of asthmatic exacerbations, to protect mother and fetus, (2) avoid status asthmaticus (severe obstruction persisting for days to weeks), (3) prevent respiratory failure, and (4) to prevent death. Additional treatment objectives during pregnancy include: (1) assure adequate fetal oxygenation, and (2) decrease or prevent fetal effects of asthma pharmacotherapy (ACOG, 2008).
Suppression of itch and tinea capitis
Published in Dinesh Kumar Jain, Homeopathy, 2022
Now it is clear that asthma of the allergic type is usually associated with eczema or urticaria that is skin lesion. In other words, skin lesions are usually associated with allergic asthma. Suppression of skin lesions never produces asthma. Another interesting finding of asthma isIt is paroxysmal. A person who is subject to asthma may be perfectly well one minute and half an hour later may be in the throes of a violent attack. An attack may last minutes, hours or days and when prolonged is termed status asthmaticus. As the attack subsides, breathing becomes gradually easier, the patient often coughs up a plug of mucus sputum and then rapidly recovers. There are many interesting features in this disease such as a personal history of skin eruptions (urticaria, prurigo and eczema), these often alternating with paroxysms of asthma.(Warner, 1964, p. 211)
Disorders of Consciousness
Published in Philip B. Gorelick, Fernando D. Testai, Graeme J. Hankey, Joanna M. Wardlaw, Hankey's Clinical Neurology, 2020
Suffocation: Aspiration of blood or vomitus.Compression of the trachea by hemorrhage or a surgical pack.Obstruction of the trachea by a foreign body.Drowning.Status asthmaticus.Strangulation.Altitude sickness.
Stress ulcer prophylaxis in children with status asthmaticus receiving systemic corticosteroids: a descriptive study assessing frequency of clinically important bleeding
Published in Journal of Asthma, 2020
Anthony A. Sochet, Sorany Son, Kelsey S. Ryan, Meghan Roddy, Eddie Barrie, Michael Wilsey, Scott D. McKinley, Thomas A. Nakagawa
Children hospitalized with status asthmaticus have been considered at higher risk for stress-related ulceration and GI bleeding from corticosteroid exposure (12). Standard care for status asthmaticus includes the early initiation of systemic corticosteroids to reduce inflammatory dysregulation associated with asthma (13). Consequently, children hospitalized with severe asthma exacerbations are frequently prescribed gastric acid suppression therapy as stress ulcer prophylaxis (SUP) with either histamine-2 blockers (H2B) or proton pump inhibitors (PPI) (14). There is a paucity of epidemiologic data to suggest a risk reduction for CIB from SUP in this specific population (8,10,12,15,16). In addition, recent publications propose SUP is not benign and may be associated with adverse events such as development of ventilator associated pneumonia (VAP), C. difficile colitis, necrotizing enterocolitis, and acute thrombocytopenia (17–23).
Usefulness of extracorporeal membrane oxygenation in status asthmaticus with severe tracheal stenosis
Published in Baylor University Medical Center Proceedings, 2020
Chibuzo Odigwe, Jake Krieg, William Owens, Cathy Lopez, Rohan Ranjit Arya
Status asthmaticus remains a lethal condition, with an estimated 2000 deaths annually in the United States.12 ECMO has also been used in refractory cases of status asthmaticus and refractory bronchospasm.13,14 In cases of intractable respiratory acidosis, where it is impossible to adequately ventilate the patient, ECMO can be an invaluable resource, as it can be much more efficient at carbon dioxide removal.12,13 This was seen in our patient with the rapid drop in her pCO2 once she was placed on VV ECMO. The major determinants of how quickly this can be achieved are the sweep gas flow and the partial pressure of carbon dioxide in arterial blood entering the membrane lung, i.e., the higher the pCO2, the higher the efficiency with which the carbon dioxide will be removed. In our case, the successful application of VV ECMO facilitated her treatment, resolved her asthma exacerbation, and supported her until her tracheal stenosis could be treated. Our case is unique, as our patient had concurrent central and distal airway obstruction with successful treatment with VV ECMO and bedside dilation of the tracheal stenosis.
Years of life lost due to bronchial asthma in Poland between 1999 and 2013
Published in Journal of Asthma, 2018
Paulina Paciej, Elżbieta Dziankowska-Zaborszczyk, Beata Ciabiada, Marek Bryła, Irena Maniecka-Bryła
Diseases of the respiratory system are the fourth leading cause of death in the Polish population, following cardiovascular diseases, malignant neoplasms and external reasons [16–18]. In 1999, they were the cause of 4.70% of all deaths of Poles, and in 2013 they caused 5.92% of all deaths. The prognosis suggests a further increase in mortality to occur in the following years, mostly associated with the increasing incidence of influenza and pneumonia [4,19]. On the other hand, the results of our study indicate a substantial improvement in the death rates due to asthma. Besides the decline in the number of deaths due to asthma from 1,480 in 1999 to 522 in 2013, the decreasing number associated with status asthmaticus draws some attention. Status asthmaticus as an exacerbation of the chronic inflammatory process in the bronchi, often complicated by the respiratory failure, is a considerable threat to life [20].