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Mefloquine
Published in M. Lindsay Grayson, Sara E. Cosgrove, Suzanne M. Crowe, M. Lindsay Grayson, William Hope, James S. McCarthy, John Mills, Johan W. Mouton, David L. Paterson, Kucers’ The Use of Antibiotics, 2017
Van Riemsdijk et al. (2002) described the effect of mefloquine relative to atovaquone–proguanil on mood and neurologic performance parameters (sustained attention, coding speed, and visuomotor accuracy) among 119 Dutch travelers (n = 58 mefloquine). Mood was assessed quantitatively using a validated profile of mood states (POMS) questionnaire that assessed changes in depression, anger, tension, fatigue, and vigor. Sustained attention, coding speeds, and visuomotor performance were tested using validated computerized tests. Mefloquine therapy resulted in a significant (p < 0.05) deterioration in depression, fatigue, and vigor relative to atovaquone–proguanil. These effects were more prevalent earlier in prophylaxis and in individuals with lower body weight (mostly women). There were no significant differences between the treatment groups in terms of neurologic function.
Psychological Distress Among HIV-Impacted African-American and Latino Males
Published in Doreen D. Salina, HIV/AIDS Prevention: Current Issues in Community Practice, 2014
Rocco Domanico, Isiaah Crawford
The Profile of Mood States (POMS; McNair, Lorr, & Droppleman, 1971) is a 65-item, 5-point adjective rating scale commonly used to identify affective mood states and mood changes. It takes five minutes to complete and delivers scores that are amenable to statistical and clinical interpretation. There are six mood factors which are tapped: Tension-Anxiety; Depression-Dejection; Anger-Hostility; Vigor-Activity; Fatigue-Inertia; and Confusion-Bewilderment. In addition to the six mood factor scores, the POMS also provides an overall Total Mood Disturbance (TMD) calculation. The respondent is asked to assess how much of a particular mood state has been experienced during the past week, including the day the scale is completed. Reliability for the POMS was determined by calculating coefficient alpha by means of the Kuder-Richardson-20 formula. The standardized item alpha for the POMS is reported to be .86 by the authors. Test-retest reliability for the measure is reported at .66, and concurrent validity is related to be .80 in comparison to clinical assessment (McNair, 1971).
Emotional Distress in African American Women with HIV
Published in Michael B. Blank, Marlene M. Eisenberg, HIV: Issues with Mental Health and Illness, 2014
Margaret Shandor Miles, Diane Holditch-Davis, Cort Pedersen, Joseph J. Eron, Todd Schwartz
The Profile of Mood States (POMS) measures transient mood states (McNair, Lorr, & Droppleman, 1971). Six mood states are rated: depressed mood (9 items), tension (15 items), anger (12 items), fatigue (7 items), confusion (7 items) and vigor (8 items). Participants rate each mood state using a 5-point Likert scale ranging from 0 (not at all) to 4 (extremely). Summated scores for each mood state as well as an overall mood score are computed. The range of scores for each mood state varies according to the number of items. Higher scores indicate a more negative mood except for vigor where higher scores indicate more vigor. The POMS has been used extensively with adults with cancer and other chronic illness including HIV (Nyenhius, Yamamoto, Luchetta, Terrien, & Parmentier, 1999). The internal consistency reliabilities in our sample are as follows: .94 for depressed mood, .84 for tension, .91 for anger, .89 for fatigue, .78 for confusion, and .84 for vigor.
Mood disturbance, but not overall diet quality, is associated with fecal microbiome diversity in free-living adults
Published in Nutritional Neuroscience, 2023
Kristen S. Smith, Molly M. Morris, Casey D. Morrow, Josh R. Novak, Michael D. Roberts, Andrew D. Frugé
The gut-brain axis (GBA) describes the bidirectional interaction between the GI tract and the brain [7] and impacts both the pathophysiology and treatment of mood disorders [8, 9]. More specifically, the microorganisms residing in the GI tract have been found to play an integral role in mental and physical health, as well as host homeostasis [10, 11]. Substantial pre-clinical evidence demonstrates that the gut microbiome influences brain function and behavior [12] and preliminary evidence supports this relationship in humans as well [12, 13]. The gut microbiome has been implicated in the etiology of a variety of mood-related conditions [14, 15]. Furthermore, patients with major depressive disorder or generalized anxiety disorder display different fecal microbiome profiles compared to healthy controls [16, 17]. A recent systematic review estimates that 35% and 22% of patients with inflammatory bowel disease experience anxiety and depressive symptoms, respectively [18]. The Profile of Mood States (POMS) questionnaire is a common tool used to measure mood and assesses transient, distinct mood states, including depression and anxiety, that feed into overall mood disturbance [19].
The effect of time of day and high intensity exercise on cognitive performances of elite adolescent karate athletes
Published in Chronobiology International, 2022
Syrine Khemila, Mohamed Romdhani, Salma Abedelmalek, Hamdi Chtourou, Mohamed Abdelkader Souissi, Emna BenTouati, Nizar Souissi
One week before the experimental period, the participants were familiarized with the equipment, experimenters and experimental procedures to minimize the learning effects during the study (Figure 1). After the familiarization sessions, each participant accomplished, in randomized and counter-balance order, two test sessions in the morning at 09h00 and the afternoon at 16h00 with only one test session per day and a recovery period of at least 72 h between two consecutive test sessions for washout (Pincivero et al. 2001). Participants and investigators were not aware of the allocation sequence before random allocation occurs. That is, before randomization, neither participants nor investigators know which participant will be allocated. Participants were asked to wear the same sportswear (karate kimono) during all test sessions. Each session started with the measurement of the oral temperature using a digital clinical thermometer (Omron, Paris, France; accuracy ± 0.1°C) inserted sublingually for at least 3 min. Bodyweight was measured to the nearest 0.1 kg using a Tanita digital scale (Tanita, Tokyo, Japan). During each session, participants completed the Profile of Mood States (POMS) questionnaire. Subsequently, the participants performed simple reaction time (SRT); choice reaction time (CRT); comparison test (COMP), mental rotation test (MRT), and distance estimation (DE). These tests were performed before and after the KST in the same order, and the rating of perceived exertion (RPE) was determined using the Borg scale (Borg 1982) immediately after the KST.
Does the quality of life differ for shift workers compared to day workers?
Published in Chronobiology International, 2020
Nita Lewis Shattuck, Panagiotis Matsangas
The 19-item Pittsburgh Sleep Quality Index (PSQI) was used to assess sleep quality (Buysse et al. 1989) with PSQI total scores >5 characterized as poor sleepers. The Epworth Sleepiness Scale (ESS) was used to assess average daytime sleepiness (Johns 1991) with a score of >10 indicative of excessive daytime sleepiness (EDS). The Insomnia Severity Index (ISI) was used to assess the severity of both nighttime and daytime components of insomnia (Bastien et al. 2001) with scores of ≥15 associated with moderate to severe insomnia. The Profile of Mood States (POMS) (McNair et al. 1971) was used to assess Total Mood Disturbance (TMD) and six dimensions of the mood construct (anger/hostility, confusion/bewilderment, depression, fatigue, tension/anxiety, vigor/activity).