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Acute CSF rhinorrhoea
Published in S. Musheer Hussain, Paul White, Kim W Ah-See, Patrick Spielmann, Mary-Louise Montague, ENT Head & Neck Emergencies, 2018
Cerebrospinal fluid rhinorrhoea occurs when there is a communication between the nasal cavity and the intracranial space, usually the anterior fossa. For this to happen there must be a breach in the nasal mucosa and the bone of the skull base and the dura mater (except in the area of the cribriform plate where there is no dural layer). Occasionally, CSF comes from the middle or posterior fossa via the middle ear space and the Eustachian tube into the nose.
HO-1: a new marker for predicting postoperative recurrence of CRSwNP
Published in Acta Oto-Laryngologica, 2023
Min-Jie Gong, Yu-sheng Wang, Miao Lou, Rui-ping Ma, Zhen-zhen Hu, Guo-xi Zheng, Ya Zhang
14 healthy controls, 31 patients with CRSsNP, and 32 patients with CRSwNP were recruited in this study. The controls were other diseases requiring nasal endoscopic treatment such as trauma and cerebrospinal fluid rhinorrhea. The diagnosis of CRSwNP and CRSsNP was determined based on physical symptoms, nasal endoscopy and CT imaging and with reference to the guidelines of the European Position Paper on Rhinosinusitis and Nasal Polyps 2012 [8]. Allergy was determined based on the patient’s history of allergy, skin prick and IgE examination. Patients with fungal sinusitis, aspirin intolerance, severe systemic immune disease and those who had used glucocorticoid or immunosuppressive therapy in the 4 weeks prior to the procedure were not included in this study. All patients with chronic rhinosinusitis were treated with an intranasal corticosteroid spray and nasal saline irrigation for 3 months after surgery. Recurrence of CRSwNP in this study was defined as a recurrence of nasal congestion and runny nose for more than one week after 12 months, and other diseases were excluded. The Medical Ethics Committee of Xi’an Jiaotong University Second Affiliated Hospital approved this study.
Locally advanced sinonasal adenoid cystic carcinomas: endoscopic endonasal surgery-centered comprehensive treatment provides benefits
Published in Acta Oto-Laryngologica, 2023
Jin Wang, Meng Zhang, Wenqi Yi, Liang Li, Liangyu Li, Chuan Pang, Lei Chen
Regarding complications caused by anterior cranial base involvement, 1 of 11 patients suffered cerebrospinal fluid rhinorrhea (water-like secretions) and intermittent fever after surgery. These symptoms were resolved following treatment with antibiotics and mannitol regimens. The CLA operations resulted in postoperative facial edema in 1 patient, but the symptom gradually resolved within one week.