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Statistical Approaches in the Development of Digital Therapeutics
Published in Oleksandr Sverdlov, Joris van Dam, Digital Therapeutics, 2023
Oleksandr Sverdlov, Yevgen Ryeznik, Sergei Leonov, Valerii Fedorov
While DTx solutions hold great promise for 21st-century medicine, it is still a relatively new field for which industry standards and best practices are yet to emerge. In addition to technical development issues, a significant challenge is the thorough clinical evaluation of DTx interventions to support the developers' claims. It has been acknowledged that existing approaches to the development of new drugs, biologics, and medical devices may be insufficient in the DTx context due to the complexity of DTx interventions, the complexity of data generated by digital technologies, and lack of established standards (Buijink et al., 2013; Tomlinson et al., 2013; Guo et al., 2020).
Sparking and Sustaining the Essential Functions of Research
Published in Thomas S. Inui, Richard M. Frankel, Enhancing the Professional Culture of Academic Health Science Centers, 2022
Eric B. Larson, Christine Tachibana, Edward H. Wagner
Back at the Group Health drawing board, lessons learned from the Access Initiative sensitized leadership to the importance of a system that had effective primary care as its first principle of design. The challenge was achieving the project goals without burning out primary care physicians and their teams. The solution that was developed is based in the CCM, which identifies specific responsibilities across a team of coordinated but diverse health-care providers and includes patients, families, and community resources. Evidence from GHRI studies demonstrated the effectiveness of collaborative care not only for chronic conditions but for the everyday demands of routine primary care. Based on this understanding, Group Health decided in 2005 to pilot the PCMH, a primary care model that addresses the complexity of 21st-century medicine while supporting the principles of good primary care.41,42 This model was recommended by the major primary care professional organizations of the time.
Unhealthy horrors
Published in Lester D. Friedman, Therese Jones, Routledge Handbook of Health and Media, 2022
With its distinctive focus on biomedical threats, new zombie media continue this biopolitical conflation of health and politics. Although influenced by 21st-century medicine, the genre reflects many aspects of older biopolitical paradigms: it conflates illness with political disorder, reduces persons to the bodily dysfunction from which they suffer, and imagines the unhealthy as dangerous masses. In its simplest form, new zombie media follow this tradition with images of pervasive zombie crowds. Within the mass, the individual zombie, and all traces of the person it was, vanish into lurching or rushing waves of infection (see Figure 19.2).
Dynamic Consent in Neuroscience Too?
Published in AJOB Neuroscience, 2021
Henri-Corto Stoeklé, Achille Ivasilevitch, Christian Hervé
In general, it should be said that, in an era of artificial intelligence and information and communication technologies (ICTs; smartphones, computer tablets, etc.), the issue of the form and content of informed consent has perhaps never been so central to medicine (Cumyn et al. 2020). Indeed, in the 21st century, medicine can no longer refuse to pay heed to the importance of these new means and modes of information sharing and exchange, which may prove necessary for its future spatial and temporal development (Stoekle et al. 2019). For consent to be legitimate, it must be based on free, measured information (Charon et al. 1996). It matters little that a particular society or individual would favor an exchange or sharing of information due to different social models or cultural representations: the only thing that really counts in a world in which it is hoped that digital information will occupy a significant place is that information circulates, as much as possible, and in the best possible way (Stoekle et al. 2019). The role of bioethics is, thus, to ensure that this circulation of information is always in the interests of all and everyone (Stoekle et al. 2020). In this context, “dynamic consent” emerges as a possible solution that is suboptimal but at least satisfactory, as it has been for some time (Kaye et al. 2015; Prictor et al. 2020; Spencer et al. 2016; Steinsbekk, Kare Myskja, and Solberg 2013; Stoekle et al. 2019; Williams et al. 2015).
Personalized Nutrition in Disrupting Cancer — Proceedings From the 2017 American College of Nutrition Annual Meeting
Published in Journal of the American College of Nutrition, 2019
Taylor C. Wallace, Scott Bultman, Chris D’Adamo, Carrie R. Daniel, Justine Debelius, Emily Ho, Heather Eliassen, Dawn Lemanne, Purna Mukherjee, Thomas N. Seyfried, Qiang Tian, Linda T. Vahdat
The future of healthcare is going to be individual focused, proactive wellness- and disease- care through personalized data clouds. This form of 21st century medicine, which we term predictive, preventive, personalized, and participatory (P4) medicine (18, 19), entails coordinated efforts from practitioners, including physicians, nutritionists, scientists, and technologists. The P4 Healthcare Alliance was established to promote P4 medicine as a new medical specialty through training, certification, and advocacy. Thought leaders and stakeholders in P4 medicine from academic, nonprofit, and commercial institutions are expected to join forces in charting this exciting new territory in medicine and healthcare.
Going the Distance: Bringing Cancer Care to the Navajo Nation
Published in Oncology Issues, 2019
“My hope is that people on reservations will dare to expect reasonable access to 21st-century medicine like any other American.” For more information, visit tchealth.org/cancer. To donate, visit: gofundme.com/launch-oncology-on-navajo. Find additional resources from Cancer Support Community at cancersupportcommunity.org/resources.