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Eclampsia
Published in Michael J. O’Dowd, The History of Medications for Women, 2020
Addressing the origin of the Veratrum alkaloids, Irving noted that they were derived from three plants belonging to the lily family. The first was Veratrum album L., the white or European hellebore; the second was Schoenocaulon officinalis Gray., the sabadilla; and the third was Veratrum viride Aiton, the green or American hellebore. Veratrone was derived from Veratrum viride. Protoveratridine, derived from Veratrum album was also employed to treat eclampsia when veratrone was withdrawn from use. Dwelling on the history of hellebore, Irving wrote that the drug had been known since the Middle Ages. He appeared to be unaware that hellebore was used by the ancients, including Soranus of Ephesus in the second century AD, in their treatment of ‘hysterical suffocation’ and that their medication found its way into the pharmacopoeia of seventeenth century obstetricians, usually administered as a sneezing powder, to treat convulsions (Wolveridge, 1671).
Part 5: Hyperactivity, Attention Deficit Disorders and Homeopathy
Published in Aruna Bakhru, Nutrition and Integrative Medicine, 2018
Fears and delusions, night restlessness, moaning and screaming, despaired and furious, prostration with icy coldness, vagotonia, fainting fits, violent vomiting and diarrhea with colic, anxious chest constriction: VERATRUM ALBUM 4CH
Inhibiting Low-Density Lipoproteins Intimal Deposition and Preserving Nitric Oxide Function in the Vascular System
Published in Christophe Wiart, Medicinal Plants in Asia for Metabolic Syndrome, 2017
Synonym: Veratrum album var. dahuricum Turcz.Subclass Liliidae, Superorder Lilianae, Order Melianthales, Family MelianthaceaeMedicinal use: epilepsy (China)
Hikers poisoned: Veratrum steroidal alkaloid toxicity following ingestion of foraged Veratrum parviflorum
Published in Clinical Toxicology, 2018
Mehruba Anwar, Matthew Turner, Natalija Farrell, Wendy B. Zomlefer, Owen M. McDougal, Brent W. Morgan
The nine species (or species complexes) of the plant genus Veratrum found in North America include: Veratrum album, Veratrum calicfornicum, Veratrum parviflorum, Veratrum tenuipetalum, and Veratrum viride [1,2]. They are generally referred to as false hellebores or bunchflowers [3]. V. parviflorum (mountain bunchflower; synonym: Melanthium parviflorum) is restricted to forested mountain slopes (at least 1700 m) in the southeastern USA [4]. Mature plants with flowering stalks are approximately 1–2 + m tall, with a short rhizome plus a small bulb, and a pseudostem formed by the overlapping sheaths of the broad, oval to elliptical leaves [2,5] (Figure 1).
The protective role of jervine against radiation-induced gastrointestinal toxicity
Published in Journal of Enzyme Inhibition and Medicinal Chemistry, 2019
Selvinaz Yakan, Tuba Aydin, Canan Gulmez, Ozkan Ozden, Kivilcim Eren Erdogan, Yusuf Kenan Daglioglu, Fundagul Andic, Onur Atakisi, Ahmet Cakir
The undervalued parts of the Veratrum album were ground in the blender without drying directly in the sun. Then, 1300×g of ground material was treated with 7.5% (3.4 mol) of diluted NH4OH and then extracted with benzene (5 L) at 40 °C in a reflux cooler. The extract was filtered, and the filtrate was concentrated by rotary evaporator at 50 °C and low pressure. At the end of this process, 24 g of the extract was obtained19.