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Monographs of essential oils that have caused contact allergy / allergic contact dermatitis
Published in Anton C. de Groot, Monographs in Contact Allergy, 2021
Salvia sclarea L., commonly known as clary sage or clary, is a biennial or short-lived herbaceous perennial, which reaches 0.9 to 1.2 meter in height and is one of the most valuable aromatic plants of the temperate region. It is native to southern Europe, central Asia and to Africa up to the Atlantic Ocean and is cultivated all over the world, commonly in the former USSR, Bulgaria, France, Morocco, USA, England, central Europe and West China. The essential oil of the clary sage serves as flavoring agent in food, liqueurs, non-alcoholic beverages and tobacco, and is used in perfumery, in the cosmetic industries and for pharmaceutical and medicinal purposes (8).
Aromatic Medicine
Published in Anil K. Sharma, Raj K. Keservani, Surya Prakash Gautam, Herbal Product Development, 2020
Sakshi Bajaj, Himangini Bansal
Clary sage (Salvia sclarea Linn.) belongs to the family of Lamiaceae. The leaves are large purple tinted furry and green in color. It is the principal source of EO in clary sage, perennial herb. It is extraordinary from, Salvia officinalis or a typical sage. Further, it tends to be differentiated by its size of leaves which are much larger than the regular one and its shading is somewhat blue white in late summer. It contains predominantly linalyl acetate, linalool, germacrene D, alpha-terpineol, geranyl acetate, and caryophyllene (Dogan et al., 2015).
Medicinal Plants of Central Asia
Published in Raymond Cooper, Jeffrey John Deakin, Natural Products of Silk Road Plants, 2020
Farukh S. Sharopov, William N. Setzer
Salvia sclarea L. (Lamiaceae) (Shalfey muskatniy (Russian), Marmarak (Tajik)) is native to the Mediterranean, North Africa, and Central Asia but is widely cultivated around the world. Infusions of the aerial parts are taken as a tonic to improve digestion and appetite, as well as a diuretic; S. sclarea fruits are used to treat dysentery and bloody diarrhea (Sharopov et al., 2015). The essential oil from the aerial parts contains linalyl acetate and linalool as major components (Sharopov et al., 2015). The aerial parts also contain oxygenated caryophyllane and salvialane sesquiterpenoids (Maurer and Hauser, 1983), abietane (tanshinone and umbelliferone) (Romanova et al., 1978), labdane (manool and sclareol) (Ulubelen et al., 1994), and amphilectane (salviatrienes A and B) (Laville et al., 2012) diterpenoids (Figure 4.15).
Sclareol attenuates the development of atopic dermatitis induced by 2,4-dinitrochlorobenzene in mice
Published in Immunopharmacology and Immunotoxicology, 2019
Po-Chang Wu, Wen-Ho Chuo, Shih-Chao Lin, Caitlin W. Lehman, Christopher Z. Lien, Chieh-Shan Wu, Chi-Chien Lin
Our current and previous studies have demonstrated that sclareol (labd-14-ene-8, 13-diol), a labdane-type diterpene compound extracted from the leaves and flowers of Clary sage (Salvia sclarea L.), possesses anti-inflammatory and immunomodulatory activities [11–13]. More specifically, sclareol profoundly decreased the productions of pro-inflammatory cytokines such as TNF-α, IL-6, and IL-17 by down-regulating the phosphorylation of the MAPK pathway. Furthermore, sclareol is one of the most commonly used essential oils utilized in aromatic therapy to treat dermatological disorders such as inflammatory dermatitis and eczema [14,15].
Safe Essential Oil Practice in Cancer Centers
Published in Oncology Issues, 2018
Tisha Throne Jones, Debra Reis
There are essential oils that may affect the effectiveness of some medications. Individuals with estrogen-dependent cancers should avoid essential oils with phytoestrogen-like activity such as aniseed (Pimpinella anisum), clary sage (Salvia sclarea), bitter fennel (Foeniculum vulgare var. amara), myrtle (Myrtus communis), and star anise (Illicium verum).5 Peppermint (type unknown) and eucalyptus (Eucalyptus globulus) should be avoided topically near an intravenous catheter site administering 5-fluorouracil because of a potential increase in medication absorption.5