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Herbal Product Development and Characteristics
Published in Anil K. Sharma, Raj K. Keservani, Surya Prakash Gautam, Herbal Product Development, 2020
Mirian Pateiro, Rubén Domínguez, Predrag Putnik, Danijela Bursać Kovačević, Francisco J. Barba, Paulo S. E. Munekata, Elena Movilla Fierro, José M. Lorenzo
Oregano is yet another herb of the Laminaceae family, cultivated in the Mediterranean area since ancient times (Figure 8.1) (Mahmoud et al., 2004). There are more than 20 species included in the genus Origanum, being Origanum vulgare L. and Origanum majorana L. the most relevant for their medicinal activity (Uritu et al., 2018). For this purpose, dried leaves and flowering tops of the aforementioned species are used (Table 8.1). Among the main beneficial properties of this herb include pasmodic, antimicrobial, digestive, and expectorant activities (Teixeira et al., 2013). Regarding its antimicrobial activity, O. majorana L. is able to inhibit the formation of microbial metabolites, and has properties related to cardiovascular disorders, such as vasodilatatory effects, and it is capable to prevent atrial fibrillation (Floria et al., 2015; Marino et al., 2001).
Atlas of Autofluorescence in Plant Pharmaceutical Materials
Published in Victoria Vladimirovna Roshchina, Fluorescence of Living Plant Cells for Phytomedicine Preparations, 2020
Victoria Vladimirovna Roshchina
Origanum vulgare L. (family Lamiaceae), the cultivated oregano culinary plant, is known as a medicinal and spice species (Bosabalidis 2002; Kintzios 2002b, 2003; Murav’eva et al. 2007; Azizi et al. 2009a, b; Shafiee-Hajiabad et al. 2014).
Extraction and Therapeutic Potential of Essential Oils: A Review
Published in Megh R. Goyal, Hafiz Ansar Rasul Suleria, Ademola Olabode Ayeleso, T. Jesse Joel, Sujogya Kumar Panda, The Therapeutic Properties of Medicinal Plants, 2019
Origanum vulgare (Oregano) is also known as origanum or wild marjoram that is a perpetual herb. It is well-known for its flavorful leaves and flowering tops. The name is resultant from the Greek word ‘oros’ means mountain, and ‘ganos’ means joy. Essential oil of oregano comprises of monoterpenoids and monoterpenes. About 60 various components are found in the oil, and the chief ones are carvacrol and thymol reaching up to 80%, whereas the remaining compounds are p-cymene, caryophyllene, spathulenol, germacrene-D, β-fenchyl alcohol and terpineol (Table 4.1) [55].
Protective and anti-inflammatory effects of hydroalcoholic leaf extract of Origanum vulgare on oxidative stress, TNF-α gene expression and liver histological changes in paraquat-induced hepatotoxicity in rats
Published in Archives of Physiology and Biochemistry, 2019
Ali Sharifi-Rigi, Esfandiar Heidarian, Sayed Asadollah Amini
Researchers and physicians emphasize on the use of antioxidants for treatment based on their constituents (Mittler 2002, Awadalla 2012). Origanum vulgare L. (Lamiaceae) which is widely found in Europe, America, North Africa, and Asia is used as spice in western diets. This plant is a rich source of phenolic compounds and monoterpenoids with high antioxidant capacity and antimicrobial activity (Zhang et al.2014, Kubatka et al.2016). Rosmarinic acid, ursolic acid, and other phenolic compounds of this plant can be introduced as influential antioxidants (Rodríguez-Meizoso et al.2006). Several studies have reported anti-mutagenic and anti-carcinogenic and especially liver protection effects of O. vulgare (Sikander et al.2013, Kubatka et al.2016). Therefore, the aim of this study was to evaluate the effects of hydroalcoholic leaf extract of O. vulgare on oxidative stress, TNF-α (tumour necrosis factor alpha) gene expression and liver histological changes in paraquat-induced hepatotoxicity in rats.
Skin hyperpigmentation treatment using herbs: A review of clinical evidences
Published in Journal of Cosmetic and Laser Therapy, 2018
Mayuree Kanlayavattanakul, Nattaya Lourith
Origanum vulgare (oregano) is a commonly known herb whose essential oil is believed to show therapeutic benefits. Origanoside isolated from maceration of the aerial portions of the plant with EtOH, followed by partitioning with EtOAc prior to preparative HPLC, proved non-cytotoxic to human fibroblasts at a maximum dose of 100 μg/ml. It was also non-cytotoxic toward B16 melanoma cells and was shown to inhibit cellular tyrosinase to levels of 16.9–28.6% at 10 and 20 μg/ml, respectively, in comparison to control untreated cells, although it proved less active than arbutin or ascorbic acid. In addition, it was exhibited to suppress MITF and TRP-2. Evaluations of origanoside clinical efficacy in C57BL/6J mice after daily topical applications (0.1 g) for 10 days showed improvements in skin lightness in terms of L* (from colorimeter measurements). Immonohistochemistry confirmed the results of noninvasive instrumental evaluations (34).
Dietary oregano extract (Origanum vulgare L.) enhances the antioxidant defence in rainbow trout, Oncorhynchus mykiss against toxicity induced by organophosphorus pesticide, diazinon
Published in Toxin Reviews, 2020
Ahmad Rafieepour, Saeed Hajirezaee, Ruhollah Rahimi
The medicinal plant, oregano, Origanum vulgare is an important Mediterranean herb rich in polyphenols, thymol, and carvacrol with antioxidant and antimicrobial activities (Lagouri et al.1993; Chun et al.2005). The ability of oregano in scavenging the ROS produced during oxidative stress has been confirmed in many studies (Lagouri et al.1993; Yanishlieva et al.1999; Kulisic et al.2004). Furthermore, several studies have shown the immunostimulating and antioxidant role of oregano in fish (Zheng et al.2009; Abdel-Latif and Khalil 2014; Haghighi and Rohani 2015; Diler et al.2017). However, there is no information associated with the protective properties of oregano against ROS resulting from pesticide-induced oxidative stress.