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Monographs of essential oils that have caused contact allergy / allergic contact dermatitis
Published in Anton C. de Groot, Monographs in Contact Allergy, 2021
Hyssopus officinalis L. is an aromatic perennial subshrub belonging to the Lamiaceae family. Hyssop is native to Northern Africa (Algeria, Morocco), temperate regions of Asia (Iran, Turkey, Caucasus) and middle, southern and eastern Europe. It is an important medicinal and culinary plant extensively cultivated in Russia, various European countries, the United States and China. The leaves and flowering tops produce a pleasantly smelling essential oil used for flavoring and food preservation, in liqueurs, cosmetic products, in perfumery, in the pharmaceutical field in several antiseptic preparations and for phytotherapeutic uses in folk medicine and aromatherapy (2).
The Role of Herbal Medicines in Female Genital Infections
Published in Megh R. Goyal, Hafiz Ansar Rasul Suleria, Ramasamy Harikrishnan, The Role of Phytoconstitutents in Health Care, 2020
Hyssopus officinalis has volatile oil, fat, sugar, choline, iodine, tannins, carotene, and xanthophylls. The tops of flower contain ursolic acid and a glucoside diosmin, which produces rhamnose and glucose. Its essential oil has been used as therapeutic agents and possesses properties, including anti-inflammatory, antiviral, antitumor, cytotoxic, antimycosis, and antimicrobial activities [41]. Method of Use: We use flower heads, leaves, the essential oil of the flowering plant and sometimes the roots. It is used as an herbal tea by the addition of 10 g or 1 teaspoon of flowering tops or dried flowers in one liter of boiling water; let infuse ten minutes and drink 2 or 3 cups a day; or is used as bath or a vaginal douche to soothe the irritation of the vagina and eliminate infections; infuse two tablespoons of hyssop into 200 ml of boiling water, then filter and apply to the irritated areas during morning and evening [83].
Gastroprotective effect of Hyssopus officinalis L. leaves via reduction of oxidative stress in indomethacin-induced gastric ulcer in experimental rats
Published in Drug and Chemical Toxicology, 2022
Mohd Tahir, Md Azizur Rahman, Mohammad Khushtar
Polyphenols being astringent and vasoconstrictor may precipitate microproteins on the site of the ulcer therapy forming an impervious protective pellicle over the lining to prevent absorption of toxic substances and to resist the attack of proteolytic enzymes. Flavonoids improve microcirculation which renders the cells less injurious to precipitating factors (Kagbo and Aduku 2015). Hyssopus officinalis L. possess chemical constituents such as flavonoids, polyphenols and tannins (Fathiazad et al. 2011). It is also reported that flavonoids, polyphenols and tannins offer antiulcerogenic effect due to their antioxidant potential (Majeed et al. 2015). Thus, the ulcer protective effect of Hyssopus leaves could be due to the presence of polyphenols such as flavonoids and tannins.
Differential effect of herbal tea extracts on free fatty acids-, ethanol- and acetaminophen-induced hepatotoxicity in FL83B hepatocytes
Published in Drug and Chemical Toxicology, 2022
Guan-Wen Chen, Tai-Yuan Chen, Pei-Ming Yang
Eight common components (Table 1) of commercial herbal tea formulations were chosen. Because herbal teas are usually prepared by decoctions and infusions, the dried herbs (either leaves or whole plants) were boiled in hot water as described in “Materials and Methods” to obtain herbal tea extracts. To investigate the effect of herbal extracts on hepatic cell growth, FL83B cells were used. FL83B, a hepatocyte cell line isolated from a normal liver of a 15-day-old mouse, exhibits common morphological features in normal liver cells (Breslow et al.1973). Therefore, FL83B cells have been widely used as a cell model for liver diseases (Lee et al.2011, Chang et al.2016, 2018, Huang et al.2017, Yeh et al.2018). FL83B cells were treated with 200, 500 and 1000 μg/mL of herbal tea extracts for 24 h, and then cell viability was analyzed by an MTT assay. As shown in Figure 1, all these herbal extracts at 200 and 500 μg/mL had no effect on the growth of FL83B cells, suggesting that herbal extracts per se at these concentrations did not exhibit hepatotoxicity. Only treatment with 1000 μg/mL of herbal extracts from Hyssopus officinalis L. and Salvia officinalis L. reduced cell viability to 73 and 72%, respectively. Therefore, the concentration, 500 μg/mL, of each herbal extract will be used for further experiments in this study.