China
Africa
Explore chapters and articles related to this topic
Medical Patients with Epilepsy
Published in Stanley R. Resor, Henn Kutt, The Medical Treatment of Epilepsy, 2020
Aluminum hydroxide, magnesium hydroxide, and calcium carbonate preparations are in wide use for the treatment of peptic ulcer disease and sundry ill-defined stomach ailments. Some of these preparations can decrease the absorption of PHT horn the GI tract, but this effect appears to be quite variable (18). A single report also suggests that the absorption of some VPA preparations can be increased by some but not other antacid formulations (20,21). When feasible, given the uncertainties of changes in VPA or PHT bioavailability during concomitant antacid therapy, these AEDs should be administered either 1 to 2 hours before or 2 hours after taking the antacid. AED plasma levels should be followed during concurrent therapy to screen for significant interactions.
Ingrowing Nail
Published in Nilton Di Chiacchio, Antonella Tosti, Therapies for Nail Disorders, 2020
Azzam Alkhalifah, Florence Dehavay, Bertrand Richert
Sodium hydroxide 10% has shown similar success rates when applied for 1 minute, with shorter period of oozing and complete healing.50–52 Both phenol29,53–55 and sodium hydroxide56,57 are effective and safe for diabetics and children.
Measurements of Energy Metabolism in the Isolated Heart
Published in John H. McNeill, Measurement of Cardiovascular Function, 2019
Rick L. Barr, Gary D. Lopaschuk
When 14CO2 is being measured, there will be waste Hyamine Hydroxide solution that needs to be disposed of. Do this by removing the air outflow line from the HH solution remaining in the Corex tube and clean it with a paper towel. (This tube must be decontaminated between hearts.) Be careful to ensure that no drops of HH fall on anything. Remove the old Corex tube and pour the waste HH into an appropriate disposal container. Rinse the old Corex tube until the water stops foaming. Do the same with any other waste Hyamine Hydroxide solution.
Oral formulation of Prussian blue with improved efficacy for prophylactic use against thallium
Published in Drug Development and Industrial Pharmacy, 2023
Nidhi Sandal, Vivek Kumar, Pooja Sharma, Mahendra Yadav
Tl adsorption of FF1-FF3 was studied in SGF (pH 2.5) and compared with F15 (PB granules only). The percentage adsorption of FF1-FF3 showed a significant increase with 2–3 times higher than F15 alone. These results indicated that the pH of SGF (pH 2.5) was increased due to the addition of pH modifying agents, resulting in increased binding of Tl to PB. However, magnesium hydroxide granules showed three times higher percentage adsorption suggesting the combination of PB granules with magnesium hydroxide granules as the best strategy to achieve the objective of the present study. Magnesium hydroxide also has the added advantage of being used in PB therapy. One of the side effects of PB therapy is constipation and the removal of fecal matter having Cs/Tl bound with PB should be excreted out at the earliest. Magnesium hydroxide suspension is recommended for easing constipation and improving the therapeutic effectiveness of PB.
A facile method for anti-cancer drug encapsulation into polymersomes with a core-satellite structure
Published in Drug Delivery, 2022
Hongchao Xu, Weiwei Cui, Zhitao Zong, Yinqiu Tan, Congjun Xu, Jiahui Cao, Ting Lai, Qi Tang, Zhongjuan Wang, Xiaofeng Sui, Cuifeng Wang
ε-Caprolactone (ε-CL, 99%, Sigma-Aldrich) was stirred over CaH2 for 24 h at room temperature and then it was distilled at reduced pressure under nitrogen. α-Methoxy-poly(ethylene glycol)44-ω-hydroxide (MeO–PEG44–OH, Mn = 2000 g/mol) was dried by co-evaporation with anhydrous toluene using a rotary evaporator. Methane sulfonic acid (MSA) was purchased from Sigma-Aldrich, and was used without further purification. Rabbit α-tubulin antibody and mouse β-Actin were purchased from Sigma-Aldrich; rabbit anti-CD31 (GB11063-2) was purchased from Servicebio; rabbit anti-Bcl-2 antibody and rabbit anti-Ki67 were purchased from Bioss; rabbit anti-MDR1/ABCB1 (E1Y7B) antibody was purchased from Cell Signaling Technology; horseradish peroxidase (HRP)-conjugated secondary antibodies were obtained from Cell signaling Technology. LysoTracker® Red DND-99 and DAPI were obtained from Thermo Scientific. Reactive oxygen species (ROS) detection kit and Annexin V-FITC apoptosis detection kit were purchased from Biovision. ECL western blotting detection kit was purchased from Millipore.
Induction of genotoxicity and differential alterations of p53 and inflammatory cytokines expression by acute oral exposure to bulk- or nano-calcium hydroxide particles in mice
Published in Toxicology Mechanisms and Methods, 2021
Based on the Organization of Economic Cooperation and Development (OECD) guidelines-420, the proper starting doses of calcium hydroxide have been detected using acute toxicity test. Following which 18 male mice were randomly distributed into 3 groups, six per each (van den Heuvel et al. 1990). Mice of the first one were orally received deionized dist. water while mice of the remained two groups were orally exposed to one dose of 2000 mg/kg ordinary- or nano-sized calcium hydroxide. Mice of all groups were noticed carefully from the first 24 h until two weeks after dosing for signs of toxicity/mortality and morphological changes/behavior as shown in Figure S1 (van den Heuvel et al. 1990). Then, the appropriate tested dose of normal-sized calcium hydroxide or calcium hydroxide nanoparticles was determined using the OECD guidelines-420 as 5% of the safety-tested dose based on OECD guidelines (Whitehead and Curnow 1992).