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Ear Microsurgery
Published in Waldemar L. Olszewski, CRC Handbook of Microsurgery, 2019
Henri Martin, Christian Martin
Anesthesia with Adrenalin® with 2% Xylocaine® may only be recommended if the operation is carried out by a perfectly trained operator and with a quite cooperative adult patient. The premedication includes, 1 hr before the intervention, an intramuscular injection of one ampule of Sedol® and coagulants (etamsylate, tranexamic acid, vitamin K, etc …). The amount of Xylocaine® generally ranges between 1 and 3 mℓ. The injection is made at 11 o’clock, at the boundary of thin skin (see Figure 1).
The Epidemiology Of Germinal Matrix/ Intraventricular Hemorrhage *
Published in Michele Kiely, Reproductive and Perinatal Epidemiology, 2019
Nigel Paneth, Jennifer Pinto-Martin
A remarkably large number of randomized trials, using a variety of pharmacologic agents, have been performed to test whether GM/IVH can be prevented. The principal drugs used have been phenobarbital, ethamsylate, vitamin E, and indomethacin. Trials of Pancuronium, vitamin K, and fresh frozen plasma have been described above. Although one would expect that randomized trials would produce reasonably consistent findings, substantial variation in results has occurred, particularly in the phenobarbital trials. A particular problem with several of the trials is inappropriate exclusion of subjects after randomization. The fundamental rule that once randomization has taken place, all infants assigned to treatment or control groups must be included in the presentation of results, appears not to be widely understood among neonatal investigators, nor indeed among the editors of some medical journals. Few trials blinded investigators by administering placebos to control groups.
Symptoms other than pain
Published in Rodger Charlton, Primary Palliative Care, 2018
Consider stopping NSAIDs and anticoagulants, and try the following instead: tranexamic acid 500 mg four times a dayorethamsylate 500 mg four times a day.
Can high-dose tranexamic acid have a role during transurethral resection of the prostate in large prostates? A randomised controlled trial
Published in Arab Journal of Urology, 2022
Mohamed Samir, Ahmed M. Saafan, Rania M. Afifi, Ahmed Tawfick
The prostate is a solid organ with a rich blood supply and surrounded by large venous sinuses [3]. As such, bleeding is one of the most common complications during TURP and TURP perioperative bleeding is associated with an ~4.4% rate of blood transfusion [16]. Many approaches have been used in attempts to reduce this bleeding, including catheter traction, intravenous oestrogen, intraprostatic vasopressin, oral ethamsylate, phenol solution, fibrin adhesive, preoperative 5α-reductase inhibitors, and goserelin acetate single dose [17].
Celiac disease and idiopathic pulmonary hemosiderosis: a literature review of the Lane–Hamilton syndrome
Published in Postgraduate Medicine, 2022
Stavros Tryfon, Efthymia Papadopoulou, Georgios Psarros, Michael Agrafiotis, Maria Saroglou
GFD was suggested at the initiation of treatment in 63.9% (23/36) patients. During the acute episode, 12/36 (33.3%) patients received blood transfusion [9,10,19,22,25,44,47,60,70,99–101], whereas iron supplementation was administered in 4 patients [19,25,44,49]. Three of the above-mentioned cases received both [19,25,44]. For the abatement of hemoptysis, etamsylate, and tranexamic acid were also administered in scarce cases [26,96].