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Fungi and Water
Published in Chuong Pham-Huy, Bruno Pham Huy, Food and Lifestyle in Health and Disease, 2022
Chuong Pham-Huy, Bruno Pham Huy
Here are some examples of the antimicrobial activity of some cephalosporins. Cefadroxil, cephradine, cefaclor, and cephalexin are used orally for the therapy of both acute and chronic upper and lower respiratory tract infections associated with Haemophilus influenzae, Streptococcus pyogenes, Klebsiella, Streptococcus pneumoniae, and S. aureus (144). Cefoxitin is more potent against the Bacteroides fragilis species and many Gram-negative and Gram-positive bacteria. Cefoxitin is also used in the treatment of pelvic and intraabdominal infections and is frequently employed as a preventive agent in patients subjected to pelvic or colorectal surgery (144).
Urinary Tract Infections, Genital Ulcers and Syphilis
Published in Miriam Orcutt, Clare Shortall, Sarah Walpole, Aula Abbara, Sylvia Garry, Rita Issa, Alimuddin Zumla, Ibrahim Abubakar, Handbook of Refugee Health, 2021
In pregnancy, treat empirically if no cultures are available. Co-amoxiclav, cephalexin and fosfomycin may be used in pregnancy. Nitrofurantoin can be used in the second and third trimester. Avoid trimethoprim, as it crosses the placenta and may affect folate metabolism.
Bacterial Skin and Soft Tissue Infections
Published in Firza Alexander Gronthoud, Practical Clinical Microbiology and Infectious Diseases, 2020
There is no cross-reaction between erythromycin and clarithromycin. Cefalexin should be avoided in severe penicillin allergy but may be considered in individuals who developed a non-severe rash to penicillin.
Prescribing patterns for treating common complications of spinal cord injury
Published in The Journal of Spinal Cord Medicine, 2023
Shikha Gupta, Mary Ann McColl, Karen Smith, Alexander McColl
The third most commonly treated condition was urinary tract infection, for which 71 prescriptions were issued to 46 participants (43% of the sample). The most commonly prescribed medications were nitrofurantoins (particularly Macrodantin/Macrobid), making up 24% (n = 17) of the prescriptions issued for this condition. Also common as the treatment for urinary tract infections, were cephalosporins (especially cephalex/cephalexin/keflex) – making up 20% (n = 14) of the prescriptions issued for this condition. Other significant categories of drugs used to treat urinary tract infections included: fluoroquinolones especially ciprofloxacin (n = 11; 15%) and beta-lactams (such as amoxicillin), trimethoprim/sulfamethoxazole, and tetracyclines (n = 5 or 7% each).
Comparative Incidence of Periocular Surgical Site Infections with Increased Surgical Mask Use during the COVID-19 Pandemic
Published in Ocular Immunology and Inflammation, 2022
Of the patients that did have an SSI, characteristics are summarized in Table 3. All SSIs were unilateral despite three patients having had bilateral surgery (blepharoplasty). Only two of eight patients had notable relevant medical histories including diabetes, obstructive sleep apnea with overnight continuous positive airway pressure (CPAP) use, and immunosuppression. Culture results could only be obtained in three of eight patients (due to absence of pus in the other five patients) and were significant for methicillin-resistant Staphylococcus aureus, Staphylococcus epidermidis, and Staphylococcus epidermidis with Citrobacter koseri. The five patients without pus were diagnosed with presumed SSI due to erythema and edema at the site. The most common antibiotic used to treat SSIs was trimethoprim-sulfamethoxazole (n = 6) and five of the patients improved within 1 week. One of the patients developed an allergic reaction to trimethoprim-sulfamethoxazole and other medications including azithromycin and doxycycline before improving with ciprofloxacin. The remaining two patients were treated successfully with cephalexin. There were no long-term complications related to SSIs in any of the patients though one patient had a residual mild hypertrophic scar.
Safety profile of laser-assisted drug delivery of vitamin C, E, and ferulic acid serum following ablative fractional resurfacing: A retrospective chart review
Published in Journal of Cosmetic and Laser Therapy, 2021
Hadley Johnson, Tiana Kazemi, Ronda S. Farah
This retrospective chart review was approved by the University of Minnesota Institutional Review Board (STUDY#00010381). Patients who underwent fractional ablative CO2 (10,600 nm) laser therapy for any diagnosis from Jan 1, 2015 to December 31, 2018 were identified utilizing a laser log at the M Health Fairview Clinics and Surgery Center. Research opt-outs and pediatric patients were excluded. Identified charts were then manually reviewed for a one-time application of a combination serum containing 15% Vitamin C, 1% Vitamin E, and 0.5% Ferulic acid (C E Ferulic®, SkinCeuticals Inc., New York, NY) within 30 minutes of laser treatment. The following parameters were also collected: age, sex, pre-procedure diagnosis, location, after-care instructions, anti-viral use, antibiotic use, and documentation of post-procedure side effects. As consistent with our institution’s normal after-care instructions, patients were advised to perform an acetic acid soak followed by application of petrolatum for 3 days post-procedure and then transition to a bland emollient (VanicreamTM or Cetaphil®). Prophylactic antiviral treatment with oral valacyclovir was initiated 1–2 days prior to the procedure for 7–14 days if the procedure was near the nose or mouth or if the patient had a history of herpetic eruption in the treatment area. Oral antibiotic prophylaxis (cephalexin or doxycycline) was administered on the day of the procedure and up to 14 days afterward if the procedure involved perioral, perinasal, or periocular areas.