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Antiseptics, antibiotics and chemotherapy
Published in Michael J. O’Dowd, The History of Medications for Women, 2020
Inflammation of the uterus was recognized as a problem throughout the Middle Ages and juice of black nightshade continued to be an important treatment. Also availed of were herbal medications with linseed or fenugreek, medicated plasters, venesection and various other remedies (Rowland, 1981). The cause of puerperal fever was not understood but the prevailing notion was that it was due to lochial retention. Thomas Raynold (1545) in The Byrth of Mankynde was of the opinion that ‘yfy woman haue the ague [fever] after her labor, for that cometh of lyke cause by retention of the flowres’.
Natural Products as Economical Agents for Antioxidant Activity
Published in Hafiz Ansar Rasul Suleria, Megh R. Goyal, Masood Sadiq Butt, Phytochemicals from Medicinal Plants, 2019
Nida Nazar, Abdullah Ijaz Hussain, Syed Makhdoom Hussain, Poonam Singh Nigam
Human are utilizing the Glycyrrhiza species (Licorice) since 4000 years to cure different diseases especially cough. More than 30 species are included in the genus Glycyrrhiza and 15 out of 30 have been studied regarding their medicinal use. Glycyrrhiza glabra is being used in the preparation of varying medicines.29 Key component of G. glabra as shown Table 8.1 is glycyrrhizic acid (triterpene glucoside), which is 50 times more sweet as compared with sugar.144 Root extract of licorice is good to cure liver diseases and its antioxidant activities were studied by performing DPPH Assay.29,58 In Indo-Pak subcontinent, Salanum nigrum L (commonly called Black nightshade) has broad uses in medicines.117 The different parts of Solanum nigrum such as stem fruit and leaves against different assays are rich source of antioxidative compounds.143
Catalog of Herbs
Published in James A. Duke, Handbook of Medicinal Herbs, 2018
Toxicity — Mortality or severe poisoning has been described for cattle, chickens, ducks, horses, sheep, and swine.14 Solanine in doses of 200 to 400 mg will induce, in humans, gastroenterosis, tachycardia, dyspnea, vertigo, sleepiness, lethargy, twitching of the extremities, cramps.33 Solanine is also said to exhibit teratogenic properties.302 Other symptoms for poisoning by the plant include diarrhea, mydriasis, panic, excitation, coma, hyperthermia, later dazed state, paralysis, rarely fatality due to respiratory difficulty and hypothermia (more normally due to respiratory paralysis). Black nightshade can contain up to 2.5% N as NO3 and can cause nitrate toxicity. In cattle acute nitrate toxicity leads to death, but chronic toxicity may lead to decreased milk yield, abortion, and impaired vitamin A and iodine nutrition. The proposed LD50 is 160 to 224 mg/NO3/kg.302
Plant poisonings in Australia: a retrospective series of calls to the Queensland Poisons Information Centre
Published in Clinical Toxicology, 2023
Tamim Islam, Robert Knoeckel, Carol Wylie, Katherine Isoardi
Across the few studies that investigate the epidemiology of plant poisonings, plant exposure patterns vary by geography. In the United States, one southwestern study reported cactus, Oleander, and Lantana as the most common plant-related exposures [6]. In New Zealand, black nightshade (Solanum nigrum), arum lily (Zantedeschia aethiopica), and kōwhai (Sophora spp.) predominate [5]. In Thailand, physic nut (Jatropha curcas), wild yam (Dioscorea hispida), and cassava (Manihot esculenta) are the most common exposures [7].
Neuroprotective properties of solanum leaves in transgenic Drosophila melanogaster model of Alzheimer's disease
Published in Biomarkers, 2022
Opeyemi B. Ogunsuyi, Tosin A. Olasehinde, Ganiyu Oboh
African eggplant (Solanum macrocarpon L) (AE) and Black Nightshade (Solanum nigrum L) (BN) leaves are tropical green leafy vegetables that has ethnobotanical values (Oboh et al. 2005, Jain et al. 2011, Haliński et al. 2012). The potential anti-ageing and neuroprotective properties of both leaves have been identified but detailed mechanisms of actions have been largely understudied (Jain et al. ).