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RADIESSE®
Published in Jani van Loghem, Calcium Hydroxylapatite Soft Tissue Fillers, 2020
Oumama Draoui, Jani van Loghem, Wouter J. Peeters, Pieter Siebenga
As with any implant material, possible adverse reactions that may occur include, but are not limited to, the following: inflammation, infection, fistula formation, extrusion, hematoma, seroma, induration formation, inadequate healing, skin discoloration and inadequate or excessive augmentation.
Augmentation of fracture fixation
Published in Peter V. Giannoudis, Thomas A. Einhorn, Surgical and Medical Treatment of Osteoporosis, 2020
Peter V. Giannoudis, Panagiotis Douras
Clinicians therefore have been seeking other options/techniques to improve the outcome of fracture stabilization in the elderly population. One technique that has gained popularity during the past decade is “bone augmentation.” Bone augmentation refers to the surgical modification of cancellous periarticular bone after injury or disease with a bone substitute material in conjunction with fracture reduction and internal fixation. This procedure is relevant to the management of fragility fractures aiming to enhance the mechanical environment of the fixation. In general terms, aims of augmentation include retardation of migration of implant and bone, provision of an environment for bone remodeling, and limitation of intrusion of synovial fluid into intra-articular fractures. However, one may argue that there are a number of questions that need to be answered regarding the role of bone augmentation, including the following: (a) In which cases is augmentation necessary, important, or beneficial?; (b) What are the types and methods of augmentation?; (c) What biomaterials should be used?; and (d) Are there any potential disadvantages?
Advanced autologous tissue flaps for whole breast reconstruction
Published in Steven J. Kronowitz, John R. Benson, Maurizio B. Nava, Oncoplastic and Reconstructive Management of the Breast, 2020
Steven J. Kronowitz, John R. Benson, Maurizio B. Nava
The volume of a flap transferred to the chest wall can sometimes be insufficient to provide a symmetrical result. Reducing the volume of the contralateral breast and augmenting the reconstructed breast in a second session are possible solutions. Augmentation can be done by placing an implant underneath the flap, by adding a second (pedicled) flap, or by lipofilling.
Clinical pharmacological innovation in the treatment of depression
Published in Expert Review of Clinical Pharmacology, 2023
Jeffrey M Witkin, Lalit K Golani, Jodi L Smith
Initial treatment with a first antidepressant medication (SSRI or SNRI) takes weeks to demonstrate a full effect if there is to be one (Table 1). If there is no response or if the treatment response is not satisfactory, antidepressant switching can be instigated; a process that continues to put patients at risk due to continued disease symptoms which can instigate potential suicide. An alternative to switching is the addition of an augmentation medication. There are two primary options for augmentation therapy: 1) antipsychotic drugs like aripiprazole (Table 2) or 2) bupropion [23–25]. The mechanisms by which augmentation helps with MDD symptoms continues to be a source of scientific inquiry, but appear to involve both increases in monoamine availability (dopamine and serotonin) to critical circuit synapses and an increase in participation of key monoaminergic receptors including dopamine, norepinephrine, and serotonin receptor subtypes [26,27].
Acute unilateral vision loss and bilateral cerebral infarction following cosmetic filler injection
Published in Orbit, 2023
Huda AlGhadeer, Mohammed Talea, Ahmed Al-Muhaylib, Osama AlSheikh, Sahar M. Elkhamary
Filler injection for facial augmentation gained popularity over the last decade.1 However, an increased number of complications, such as allergic reactions, granule formation, skin necrosis, or cellulitis, and ophthalmic and retinal artery occlusion or embolization, have been reported following injection.1 Blindness after facial injection of particulate material was reported first in 1963.1 It is a rare but devastating complication associated with the cosmetic injection of the face. The current case is noteworthy because it reports permanent monocular vision loss caused by an injection of hyaluronic acid filler into the nasal bridge secondary to optic nerve infarctions. Although the patient’s identity remains unknown, her prior informed consent was taken to publish identifiable photographs.
Breast augmentation under local anesthesia with intercostal blocks and light sedation
Published in Journal of Plastic Surgery and Hand Surgery, 2023
Martine Ditlev, Erik Loentoft, Lisbet R. Hölmich
A total of 335 female patients underwent bilateral augmentation mammoplasty using the presented anesthetic technique; there were no cases of unilateral augmentation. The median patient age was 35 years with a wide range of 17–78 years. As might have been expected, the youngest patient belonged to the primary augmentation cohort whereas the oldest was found in the implant replacement cohort. Nineteen women had primary augmentation combined with a lift of the breast and thirteen women had additional procedures, such as liposuction, scar revision, and blepharoplasty performed during the same surgery. Within the implant replacement cohort, two women combined surgery with a breast lift and seven women with additional procedures (data not shown). The implants were all textured and during the first 5 years Mentor implants were used, hereafter Eurosilicone. Time used for the anesthesia and the surgical procedure was generally about 2 h in total, and time in the recovery room was generally 1–2 h, however, this was not registered on an individual basis. Patient follow-up ranged from 0 to 12.5 years with an average of 2 years. Table 1 summarizes the patient demographics, and the surgical characteristics are listed in Table 2.