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Cleansing of Hair
Published in Dale H. Johnson, Hair and Hair Care, 2018
Alpha-olefin sulfonates have excellent “flash” foaming and are stable over a wide range of pH (88), but these advantages are somewhat negated by the difficulties of viscosity control and consistency. In addition to variations among supplier sources, there could also be variations from batch to batch from any one source (175). Extra care is indeed required to ensure uniformity of viscosity characteristics in finished products. This consideration is perhaps one reason why alpha-olefin sulfonates have not been as widely used as their advantages would suggest. The frequency of use as a primary cleansing agent in shampoos is believed to be less than 10% (88). Sodium C14–16 olefin sulfonate is the most prominent one within this category.
Polymer/Surfactant Interaction in Applied Systems
Published in E. Desmond Goddard, James V. Gruber, Principles of Polymer Science and Technology in Cosmetics and Personal Care, 1999
E. Desmond Goddard, James V. Gruber
Direct evidence of the adsorption of cationic polymers on skin from an anionic surfactant system has been reported by Goddard and Leung . The authors determined the uptake of Polymer JR 125, on stratum corneum (SC) in the presence of three anionic surfactants [SDS, alfa olefin sulfonate (AOS), and alkyl 2EO sulfate] and a coco-betaine surfactant. Even though the conditions involved 30 min of exposure to the substrate, the results obtained are indicative of the trends that can be expected under normal conditions. The results reproduced in Figure 3 show that the uptake of the polymer is initially reduced markedly by the surfactants. Interestingly, at surfactant concentrations above about , the polymer uptake in fact increases and at the extent of uptake is in fact higher than that obtained in the absence of the surfactant. Note that the surfactant concentrations are
Micellar solubilization of poorly water-soluble drugs: effect of surfactant and solubilizate molecular structure
Published in Drug Development and Industrial Pharmacy, 2018
Zahari Vinarov, V. Katev, D. Radeva, S. Tcholakova, N. D. Denkov
A total of 19 surfactants were used to investigate the relationship between drug solubilization and surfactant molecular structure see Table 1. We studied systematically the effect of surfactant charge, head group type, and chain length. Two groups of nonionic surfactants were studied: polysorbates and alcohol ethoxylates. We have also studied homolog series of anionic surfactants of the alkyl sulfate type, with hydrophobic chain lengths of C10, C12, and C14. Additional anionic surfactants studied are the ethoxylated alkylsulfates, linear alkylbenzene sulfonate, and alpha olefin sulfonate. The cationic surfactants we have used are homolog series of TABs with hydrophobic chain lengths of C12, C14, and C16. The used abbreviations and properties of the studied surfactants are summarized in Table 1. Although some of these surfactants are toxic and rarely used in drug delivery, we included them in this study to clarify the general trends (viz. effect of surfactant charge).