Vesiculovirus – Knowledge and References

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Order Mononegavirales

Published in Paul Pumpens, Peter Pushko, Philippe Le Mercier, Virus-Like Particles, 2022

Paul Pumpens, Peter Pushko, Philippe Le Mercier

The Rhabdoviridae family, which is the largest family of the Mononegavirales order, contains bullet-shaped and bacilliform viruses (shown in Figure 31.1e) and consists of 3 subfamilies, 40 genera with 246 species (Walker et al. 2018). The most popular representatives of the Rhabdoviridae family are rabies virus (RABV) of the Lyssavirus genus and vesicular stomatitis virus (VSV) of the species Indiana vesiculovirus from the genus Vesiculovirus. The VSV is one of the classical objects and subjects of modern virology, immunology, and gene therapy. Infectious hematopoietic necrosis virus (IHNV) of the Salmonid novirhabdovirus species, genus Novirhabdovirus, remains a global burden of fishery, since it causes the disease known as infectious hematopoietic necrosis in salmonid fish such as trout and salmon.

A tool with many applications: vesicular stomatitis virus in research and medicine

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Journal Information

Published in Expert Opinion on Biological Therapy, 2020

Altar M. Munis, Emma M. Bentley, Yasuhiro Takeuchi

VSV is a species of the genus vesiculovirus which belongs to the rhabdovirus family [3]. Vesiculovirus is the first described virus of the 16 rhabdovirus genera, it naturally targets farm animals and causes lesions in the mouth and udders [4]. VSV is considered to be the prototype virus of the genus while other major serotypes include Cocal, Vesicular stomatitis virus New Jersey strain, Chandipura, Maraba, and Piry viruses [5–7].