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DRCOG MCQs for Circuit B Questions
Published in Una F. Coales, DRCOG: Practice MCQs and OSCEs: How to Pass First Time three Complete MCQ Practice Exams (180 MCQs) Three Complete OSCE Practice Papers (60 Questions) Detailed Answers and Tips, 2020
Asymptomatic bacteriuria in pregnancy may be associated with:Escherichia coli infection.> 100,000 bacteria ml-1 urine.30% risk of acute pyelonephritis in pregnancy.Preterm labour.Proteus mirabilis infection.
Urinary Tract Infections (UTI)
Published in Manit Arya, Taimur T. Shah, Jas S. Kalsi, Herman S. Fernando, Iqbal S. Shergill, Asif Muneer, Hashim U. Ahmed, MCQs for the FRCS(Urol) and Postgraduate Urology Examinations, 2020
Nish Bedi, Ali Omar, Jas S. Kalsi
Urea-splitting bacteria are Proteus, Klebsiella, Pseudomonas, Providencia, Serratia species, Staphylococcus aureus and Ureaplasma urealyticum. Proteus mirabilis accounts for more than half of all urease positive urinary infections [6]. Urea-splitting bacteria change the urine pH (>7.2) and allow easier precipitation of phosphate with several compounds, mainly ammonium and magnesium [7]. The result is struvite stones.
Unexplained Fever In Infectious Diseases: Section 2: Commonly Encountered Aerobic, Facultative Anaerobic, And Strict Anaerobic Bacteria, Spirochetes, And Parasites
Published in Benedict Isaac, Serge Kernbaum, Michael Burke, Unexplained Fever, 2019
Proteus infections are generally nosocomial and involve multiresistant strains. They are difficult to control, partly because of frequent antibiotic resistance and partly because they predispose to urolithiasis which may cause urinary stasis, thereby maintaining bacterial viability despite appropriate antibiotic treatment. Most Proteus bacteremias are linked to urinary tract infection or instrumentation and a smaller part to biliary, gastrointestinal, and ENT infections.
Increased demand of urine cultures from Danish general practice: a five-year register-based study
Published in Scandinavian Journal of Primary Health Care, 2023
Michael Adelsen Jakobsen, Mia Carøe Sørensen, Jette Brommann Kornum, Alina Zalounina Falborg, Malene Plejdrup Hansen
No significant change in the proportion of E. coli (RR = 1.02, 95% CI 1.00–1.04) and remaining bacteria (RR = 1.01, 95% CI 0.96–1.07) was seen when comparing the year 2017–2018 with the year 2021–2022. However, a trend of increase in Proteus spp. (RR = 1.14, 95% CI 0.98–1.34) and polymicrobial (RR = 1.10, 95% CI 1.00–1.22) was noticed. Furthermore, a minor constant decrease in the proportion of Enterococcus spp. (RR = 0.97, 95% CI 0.96–0.99, test for trend) and Klebsiella spp. (RR = 0.97, 95% CI 0.95–0.99, test for trend) was observed across all five years. Distribution of the various uropathogens varied depending on patient gender and age (Figure 3). E. coli was most common in females within all age groups. Importantly, E. coli was shown to be less prevalent in patients aged >65 years, especially in males. Both Klebsiella spp. and Enterococcus spp. were more commonly identified in urine cultures from male than female patients. In addition, S. saprophyticus and Group B Streptococci were most frequently identified in females, especially in patients aged 15–65 years.
Proteus Syndrome: Case Report with Anatomopathological Correlation
Published in Fetal and Pediatric Pathology, 2022
Javier Arredondo Montero, Mónica Bronte Anaut, Juan Carlos López-Gutiérrez
Proteus syndrome, first described in 1979, occurs in 1 per 1,000,000 live newborns. Caused by a somatic mosaicism associated with a heterozygous pathogenic variant in AKT1, the clinical picture consists of an asymmetric and disproportionate overgrowth of bone, skin, adipose tissue, and central nervous system during infancy, becoming progressively disfiguring. Similarly, associations have been established between Proteus syndrome and various neoplastic entities, as well as with thrombosis and pulmonary pathology. Diagnostic criteria include mosaic distribution of lesions, progressive clinical course, and sporadic onset of the disease, as well as the presence of cerebriform connective tissue nevus (Category A), disproportionate limb growth (Category B) and adipose tissue dysregulation (Category C) among others.
Intravenous fosfomycin for the treatment of patients with bone and joint infections: a review
Published in Expert Review of Anti-infective Therapy, 2022
Katerina G. Tsegka, Georgios L. Voulgaris, Margarita Kyriakidou, Anastasios Kapaskelis, Matthew E. Falagas
The pathogens were isolated from blood cultures, synovial fluid or tissue cultures. Not always a pathogen was isolated in the cases studied, whilst, on the other hand, in several cases, the infection was polymicrobial. In the majority of the cases, the isolated pathogen was Staphylococcus aureus (n = 142), including MRSA (n = 9). Coagulase-negative Staphyloccocus was another pathogen found frequently (n = 31), including methicillin resistant coagulase-negative Staphyloccocus (n = 10). In 20 more patients the isolated pathogen was Staphylococcus spp. Streptococcus spp. grew in 29 cases, while Pseudomonas aeruginosa was isolated in 20 cases. Several other pathogens were less frequently isolated, including Proteus spp. (n = 16), Enterococcus spp. (n = 13) and E. coli (n = 12).