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The Dental Cyst
Published in Wilson Harvey, Alan Bennett, Prostaglandins in Bone Resorption, 2020
A good working definition of a cyst has been given by Killey et al.3 an abnormal cavity in hard or soft tissue containing fluid or semifluid, often encapsulated and lined by epithelium. Dental cysts are benign lesions causing bone destruction in the mandible or maxilla which are usually detected on routine radiography or occasionally when they produce swelling. There are three main groups of cyst which occur in the jaws: “odontogenic cysts”, which arise from the epithelium concerned with tooth development, “fissurai cysts”, arising from epithelial inclusions at the closure lines of embryonic processes, and “bone cysts”, which do not have an epithelium or epithelial etiology and also occur elsewhere in the body. The odontogenic cysts are by far the most common type of cyst and are comprised of three main types.
The Structure of Odontogenic Cysts
Published in Roger M. Browne, Investigative Pathology of the Odontogenic Cysts, 2019
In contrast to the macroscopic, the microscopic appearances of the different forms of odontogenic cyst are important in their identification and in contributing to an understanding of their pathogenesis. A summary of the main histological features of each type of odontogenic cyst follows.
Surgical and other investigations
Published in John Dudley Langdon, Mohan Francis Patel, Robert Andrew Ord, Peter Brennan, Operative Oral and Maxillofacial Surgery, 2017
The precise diagnosis of odontogenic cysts depends on their relationship to teeth and radiographic details should be submitted on the Request Form. When feasible, teeth should be submitted with the soft tissue in situ. In order for thin sections to be cut, specimens containing teeth and bone need to be softened by immersion in acid following their macroscopic assessment in the laboratory. This delays the diagnosis by days or weeks depending on specimen size and composition.
Odontogenic myxoma involving the right nasal cavity, orbital floor, and skull base in a 20-year-old woman: Removal and review of the literature
Published in Acta Oto-Laryngologica Case Reports, 2023
Danlin Huang, Fei Liu, Junyi Liang, Xiao Xing, Xingsha Wu, Shuai Yang, Xinfeng Wei, Shuo Li
According to the previous study, OM is a rare benign tumor and had overlapped clinical features with other diseases, which leads to being easily confused with other jaw tumors. However, the lesion causes the CT to show a cystic component with low signal separation in the focal area, which suggests a high possibility of OM [10]. The preoperative clinical data could not provide efficient evidence to identify the patient as an Odontogenic myxoma tumor. Besides, this cystic hypodense lesion was more likely to be diagnosed as an odontogenic cyst according to its features in preoperative CT. To exclude intraosseous cystic lesions, central giant cell lesions, ameloblastomas, odontogenic keratotic cysts, or other osteolytic lesions, the preoperative diagnosis should be validated by pathologic biopsy.
Peripheral intraosseous carcinoma arising from a recurrent odontogenic keratocyst
Published in Baylor University Medical Center Proceedings, 2023
Isherpreet Shergill, Thomas Schlieve, Fayette Williams, Roderick Kim, Daniel Hammer
PIOC is a rare carcinoma that arises from the direct transformation of odontogenic epithelial rests in the jaw. The carcinogenic process is similar in PIOC and oral squamous cell carcinoma, but the tumors exhibit different oncogenes and tumor markers, indicating different genetic pathways.2 The incidence has been estimated at 0.3% to 3%.3 PIOC has a predilection for the mandible (79%) compared to the maxilla (21%). In the mandible, the posterior region is most commonly involved, while in the maxilla, the anterior region is affected.3 Clinical features such as pain, sensory disturbances without history of trauma, swelling, perforation of buccal and lingual cortical plates, adherence of the cyst lining to the bony cavity, and chronic sinus tracts are common findings.4 Malignant transformation of the odontogenic cyst epithelium due to long-standing chronic inflammation might be the main predisposing factors.5,6 Persistent infections associated with odontogenic cysts should encourage the surgeon to consider the possibility of an underlying malignancy.7
Human cytomegalovirus is present in the odontogenic epithelium of ameloblastoma
Published in Journal of Oral Microbiology, 2021
Mohammed Amjed Alsaegh, Sudhir Rama Varma, Alaa Muayad Altaie, Shengrong Zhu
Odontogenic lesions are a group of diseases that originate from the remnant odontogenic tissues in the jaws and cause morbidity to the maxilla and the mandible. While these tissues are present in all individuals, the factor behind their activation and further development of odontogenic cysts and tumours is poorly understood.