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Allergic Diseases of the Eye
Published in Pudupakkam K Vedanthan, Harold S Nelson, Shripad N Agashe, PA Mahesh, Rohit Katial, Textbook of Allergy for the Clinician, 2021
He was not able to get an appointment for the ophthalmologist, but returned a week later with complete resolution of the symptoms and disappearance of the conjunctival redness and swelling. Topical steroids were stopped and he was asked to continue the Olopatadine till he could see the ophthalmologist. He returned in three days with a recurrence of the symptoms and signs. Loteprednol was restarted, and this time continued for two weeks, before reduction in dosage and gradual tapering. A visit to the ophthalmologist confirmed the diagnosis of vernal conjunctivitis. The boy remained symptom free through the summer on Olopatadine, apart from one episode of itching which responded to addition of loteprednol for two weeks. Olopatadine was discontinued when he rejoined school in the fall term, with no recurrence. His parents have been told that it will probably be advisable to restart the drop in March-April of the following year.
The eye and orbit
Published in Professor Sir Norman Williams, Professor P. Ronan O’Connell, Professor Andrew W. McCaskie, Bailey & Love's Short Practice of Surgery, 2018
Professor Sir Norman Williams, Professor P. Ronan O’Connell, Professor Andrew W. McCaskie
Vernal conjunctivitis (Figure44.25) is a form of allergic conjunctivitis, characterised by itchy eyes, usually worse in the spring and early summer and often associated with other allergic problems such as hay fever. Clinically, most signs are under the upper lid, which may have a cobblestone appearance instead of a smooth surface.
Pediatric versus Adult Corneal Collagen Crosslinking: Long-term Visual, Refractive, Tomographic and Aberrometric Outcomes
Published in Current Eye Research, 2021
Ömür Ö. Uçakhan, Tuna Celik Buyuktepe, Zeynep Yavuz, Penny A. Asbell
An important issue is the “definition” of progression. Indeed, there is no consensus about the definition of progression after CXL. A common parameter used is an increase of more than 1.0 diopter in Kmax. However, consistently measuring and documenting a progression of 1.0 diopter can be challenging, particularly in advanced cases or in contact lens wearing eyes. It has been argued that Kmax may also not be the best parameter to use for progression in tomography systems.30 There is certainly need for development of better and more reproducible parameters to detect corneal ectatic disease progression/regression, however, using the current definition, our failure rate was quite low in both pediatric and adult age groups (1.2% in pediatric population, 0.68% in the whole sample). Although the exact reasons for this favorable outcome is unknown, meticulous treatment of any co-existant morbidity such as allergic or vernal conjunctivitis, vigorous consultation against eye rubbing and frequent use of topical antihistamine-mast cell stabilizing drops for extended periods when required, can be few underlying factors.
The ocular surface, coronaviruses and COVID‐19
Published in Clinical and Experimental Optometry, 2020
Mark Dp Willcox, Karen Walsh, Jason J Nichols, Philip B Morgan, Lyndon W Jones
CD209 can be found on human corneal dendritic cells.35 CD26 is not expressed in normal conjunctival tissue, and has only been found, and then only weakly expressed, in vascular endothelial cells of conjunctival tissue from biopsies of vernal conjunctivitis patients.37 The only report of CD66e in the conjunctiva was from patients with trachoma who had gene expression in their upper palpebral conjunctiva.39 There are no reports of CD26 or CD66e in cornea or tears. CD13 has not been reported on conjunctival or corneal epithelial cells, but has been found on human corneal keratocytes.43 9‐O‐acetylated sialic acid has been found in human tears and on human corneal mucin.44 Heparan sulfate has been found on human cornea and conjunctiva cells.200845,46
Exercise-induced bronchospasm and its associated factors among secondary school students in an urban community
Published in Alexandria Journal of Medicine, 2020
A. O. Odeyemi, A. O. Odeyemi, O. V. Kayode, S. B. A. Oseni, O. A. Oyedeji
In our study, allergic (vernal) conjunctivitis and allergic rhinitis were significantly associated with the development of EIB. This finding is in agreement with previous studies [5,6,33]. Atopy (allergy) is a major risk factor for the development of EIB. Epidemiologic data has demonstrated allergic rhinitis in up to 40% of Pediatric population with EIB [2]. Allergic sensitization induces systemic Type-2 T helper-cell immunity which predisposes the individual to airway inflammation thus promoting hyper-reactivity [2]. Eczema and a past history of wheeze were not significantly associated with EIB. Although history of wheeze has been reported in some studies to be associated with EIB [5,6], our finding was quite different. The disparity in findings may be explained by the fact that only one subject had eczema and past history of wheeze. Furthermore, individuals with present history of wheeze and those who had rhonchi on auscultation were excluded from the study.