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Special Senses
Published in Pritam S. Sahota, James A. Popp, Jerry F. Hardisty, Chirukandath Gopinath, Page R. Bouchard, Toxicologic Pathology, 2018
Kenneth A. Schafer, Oliver C. Turner, Richard A. Altschuler
Corneal deposits often consist of mineral. Some deposits are a feature of corneal dystrophy, but others may be due to other causes (Peiffer et al. 1994; Taradach et al. 1981). Corneal dystrophy is a spontaneous, noninflammatory, bilateral corneal change that occurs in several laboratory animals (Moore et al. 1987; Port and Dodd 1983; Shibuya et al. 2001). Microscopically, the finding consists of mineralized deposits along the corneal epithelial basement membrane (Bruner et al. 1992; Carlton and Render 1991a; Hoffman et al. 1983; Losco and Troup 1988). A high spontaneous incidence of corneal mineralization has been reported in Wistar Hannover rats, being greater in males compared to females, with a hypothesis proposed that in response to mineralization, keratocytes become active to play an important role in responding to the mineralized substance (Hashimoto et al. 2013). Mineralized deposits in the cornea adjacent to the palpebral fissure are referred to clinically as band keratopathy.
The parathyroid glands
Published in Professor Sir Norman Williams, Professor P. Ronan O’Connell, Professor Andrew W. McCaskie, Bailey & Love's Short Practice of Surgery, 2018
Professor Sir Norman Williams, Professor P. Ronan O’Connell, Professor Andrew W. McCaskie
PHPT may present with pancreatitis, although it is rarely seen in patients with milder forms of the disease. Common epidemiologically linked disorders, such as hypertension and peptic ulcer disease, are often encountered. Clinical examination is usually normal. Band keratopathy, pathognomonic of the disease and due to deposition of calcium phosphate crystals in the cornea, is now rarely identified.
How to master MCQs
Published in Chung Nen Chua, Li Wern Voon, Siddhartha Goel, Ophthalmology Fact Fixer, 2017
Serum ACE concentration is often elevated in active sarcoidosis and its concentration reflects the activity of the disease. Pulmonary fibrosis is a complication giving a restrictive pattern on pulmonary function test. Skin anergy is common and the Mantoux test may be negative in those with previous BCG vaccination. Band keratopathy usually results from hypercalcaemia. The presence of retinal periphlebitis increases the risk of neurosarcoidosis.
Effect of the Presence of Silicone Oil in the Anterior Chamber After Complicated Retinal Detachment Surgery on Corneal Morphology by In Vivo Confocal Microscopy
Published in Current Eye Research, 2023
Murat Kasikci, Sabahattin Sul, Huseyin Cem Simsek, Aylin Karalezli, Merve Simsek, Safak Korkmaz
We observed that endothelial cell density decreased as the size of hyperreflective stromal deposits increased. This might be an indication of silicone oil toxicity in the cornea, and its existence suggests the development of SK. Similar hyperreflective deposits were detected in the corneal stroma, particularly in the posterior stroma, in a report including 8 patients with silicone oil in the anterior chamber.21 Previous histological studies have suggested that deposits in the corneal stroma may be related to calcium deposits in the eyes with band keratopathy produced by silicone oil tamponade, with a metabolic problem in the endothelium and stroma as a probable reason.11 Nevertheless, as demonstrated in our research, the exact nature of the deposits has not been fully explained, as many of them have been detected in the transparent cornea using IVLSCM. Moreover, the link between the development of stromal deposits and corneal endothelial cell lesions is unknown and requires further studies.
Ocular Involvement in Muckle-Wells Syndrome
Published in Ocular Immunology and Inflammation, 2020
Sukru Cekic, Ozgur Yalcinbayir, Sara Sebnem Kilic
Mean BCVA was 0.48 ± 0.81 logMAR units in this study (range: 0.0 to 3.0). Examination of ocular motility and alignment of cases were completely normal except for the index patient who had bilateral acquired pendular nystagmus and quite low vision. Anterior segment biomicroscopy showed that band keratopathy was present in four eyes of the two patients; namely in the index patient and the patient who had cataract removal. Corneal leukoma due to corneal scarring was present in both eyes of another patient who was a 42-years-old female (patient H in Tables 1 and 2). In this patient, corneal topography demonstrated central flattening as well as surrounding steepening (Figure 2). Posterior stromal corneal opacification with edema and accompanying anterior iris snychecia was present in one eye of the index patient (Figure 3). Mild cataract was present in the other eye of the index patient that had received dexamethasone implant for uveitis. Clinical signs consistent with past uveitis (e.g. pigment on the anterior lens capsule, hyalinized keratic precipitates) were present in four eyes of three individuals. (Table 2).
The Clinical Characteristics of Pediatric Non-Infectious Uveitis in Two Tertiary Referral Centers in Turkey
Published in Ocular Immunology and Inflammation, 2021
F. Nilüfer Yalçındağ, Sirel Gür Güngör, Mehmet Fatih Kağan Değirmenci, Almila Sarıgül Sezenöz, Zeynep Birsin Özçakar, Esra Baskın, Fatma Fatoş Yalçınkaya, Huban Atilla
Surgical intervention was needed in only a minority of the patients (5.2%) in our study. Cataract extraction was reported as the most common surgical procedure needed in pediatric uveitis patients in the literature before.16,23 In a study by Ganesh et al. 54.5% of surgical interventions needed were cataract removal.16 Unlike previous reports only one patient needed cataract removal in our cohort group, while one patient underwent trabeculectomy, two underwent pars plana vitrectomy and one patient underwent keratectomy EDTA chelation and amniotic membrane transplantation. Although this is not a standard procedure for treatment of band keratopathy, we choose this procedure to accelerate healing process in this individual case.