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Thoracic cases
Published in Lt Col Edward Sellon, David C Howlett, Nick Taylor, Radiology for Medical Finals, 2017
Hannah Adams, Sarah Hancox, Cristina Ruscanu, David C Howlett
Appearances of lung metastases on CXR include (see Table 5.4):Cannonball appearance.Ill-defined ‘snowstorm’ appearance (Figure 5.4C).Solitary lung nodule (+/- cavity).Multiple lung nodules (+/- cavities, Figure 5.4D, page 70).Miliary nodularity (military = seed = fine and small, 1–3 mm).Lymphangitis carcinomatosa.
Pulmonology
Published in Fazal-I-Akbar Danish, Essential Lists of Differential Diagnoses for MRCP with diagnostic hints, 2017
↓ Gas transfer factor (TLCO6 and KCO7):1 COPD.2 Restrictive airway disease (interstitial lung disease).3 Pneumonia.4 Pulmonary oedema.5 Pulmonary embolism.6 Pulmonary hypertension.7 Pneumonectomy.8 Anaemia.9 AVM.10 Lymphangitis carcinomatosa.
Breathlessness in Pregnancy: Respiratory Causes
Published in Tony Hollingworth, Differential Diagnosis in Obstetrics and Gynaecology: An A-Z, 2015
Lymphangitis carcinomatosa occurs in advanced metastatic breast cancer, and can cause severe breathlessness and dry cough. As with drug-induced interstitial lung disease, there may be profound hypoxia.
Pulmonary lymphangitis carcinomatosis: systematic review and meta-analysis of case reports, 1970-2018
Published in Postgraduate Medicine, 2019
Pulmonary lymphangitic carcinomatosis (PLC), also called pulmonary lymphangitis carcinomatosa, is a rare form of metastatic lung disease in which advanced malignant tumors spread diffusely through pulmonary lymphatic vessels. The most frequent symptom is increasing dyspnea that can aggravate quickly and severely. A difficult outflow of lymph from the lungs causes the accumulation of interstitial fluid and oxygen diffusion disorders that tend to cause respiratory dysfunction. Radiological changes occur late and symptoms can be anterior to radiological signs takt could lead to dyspnea, which is usually more severe than clinical and radiological findings. Moreover, misleading clinical presentation may imitate the symptomatology of congestive heart failure, pneumonia, pulmonary emboli, asthma, sarcoidosis, pulmonary fibrosis, pulmonary cancer and metastasis, and radiation-induced lung disease [1–5].
Biophysical and photobiological basics of water-filtered infrared-A hyperthermia of superficial tumors
Published in International Journal of Hyperthermia, 2018
Peter Vaupel, Helmut Piazena, Werner Müller, Markus Notter
Using an upgraded, thermographically controlled 2-wIRA-radiator system, Notter et al. [13] have treated large-sized (broad, superficial) heavily pretreated breast cancer recurrences (and re-recurrences) with wIRA immediately followed by hypofractionated RT (5 × 4 Gy, 1/week). Response rates in this retrospective study were 61% CR and 33% PR, respectively. Local control throughout lifetime after CR of macroscopic disease was 59%. Despite larger tumor sizes and a higher percentage of superficial lymphangitis carcinomatosa, the CR rate was comparable to data published in a recent review by Datta et al. [14]. From this latter systematic review with meta-analysis of combined HT and RT for locoregionally recurrent breast cancer (LRBC) it is concluded that ‘thermoradiotherapy is an efficient and safe palliative treatment option for LRBCs’. Due to the level of evidence, hyperthermia combined with RT has been recommended by current breast cancer guidelines in the USA, in the Netherlands and in Germany [15–19].