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DRCOG MCQs for Circuit A Questions
Published in Una F. Coales, DRCOG: Practice MCQs and OSCEs: How to Pass First Time three Complete MCQ Practice Exams (180 MCQs) Three Complete OSCE Practice Papers (60 Questions) Detailed Answers and Tips, 2020
Malignant ovarian tumours include: Clear cell tumour.Brenner tumour.Granulosa cell tumour.Dysgerminoma.Krukenberg.
B
Published in Anton Sebastian, A Dictionary of the History of Medicine, 2018
Brenner Tumor A peculiar neoplasm of the ovary, described as ‘oophoroma folliculare’ by German physician, Fritz Brenner (1877–1969) in 1907. He graduated from Heidelberg in 1904 and, after working with Eugen Albrecht at his pathology institute, he emigrated to South Africa in 1910. A similar neoplasm of the ovary was described by Ernst Gottlob Orthmann (1858–1922) in 1899.
Test Paper 5
Published in Teck Yew Chin, Susan Cheng Shelmerdine, Akash Ganguly, Chinedum Anosike, Get Through, 2017
Teck Yew Chin, Susan Cheng Shelmerdine, Akash Ganguly, Chinedum Anosike
The solid fibrous component of fibroma, fibrothecoma and cystadenofibroma characteristically demonstrates very low T2 signal intensity. With T1-weighted sequences, fibrothecomas demonstrate non-specific hypo- to isointensity with mild enhancement following the intravenous administration of a gadolinium chelate. Brenner tumour is an uncommon epithelial-stromal tumour. The fibrous components, as well as calcifications (when present), are markedly hypointense on T2-weighted MR images. Exophytic subserosal leiomyoma have low T2 signal with low to intermediate T1 signal on MRI. The ‘bridging vessel’ sign represents tortuous vascular structures passing between the uterus and the lesion and may be seen at US; however, this sign is most clearly depicted at gadolinium-based contrast material–enhanced T1-weighted imaging or T2-weighted imaging, which nicely demonstrate vascular flow voids.
Mucinous cystadenoma with fibroma: a rare combination of collision tumour
Published in Journal of Obstetrics and Gynaecology, 2022
Tanisha Singla, Chintamani Pathak, Anam Singh, Gaurav Singla, Swati Singla, Naveen Kumar R.
To correctly diagnose this tumour, one must differentiate it from fibroma with cystic changes and mucinous cystadenofibroma. The presence of columnar lining of the cysts ruled out fibroma with cystic change and absence of glandular structures in fibroma with presence of distinct interface between solid fibrous part and mucinous cystic part ruled out mucinous cystadenofibroma. The absence of transitional epithelium differentiated this tumour from Brenner Tumour with mucinous metaplasia or associated with a mucinous cystadenoma. Also, another important differential diagnosis is composite tumours (Lewin 1987) (e.g. malignant mixed Mullerian tumour) which are characterised by intermingling of different components in one neoplastic mass, as opposed to collision tumours, which show distinct interface between the two components.
A retrospective study of the epidemiology and histological subtypes of ovarian epithelial neoplasms at Charlotte Maxeke Johannesburg Academic Hospital
Published in Southern African Journal of Gynaecological Oncology, 2021
Three cases from the present study showed mixed histological findings: one case demonstrated a mucinous cystadenoma with a Brenner tumour in one ovary and a serous cystadenoma in the contralateral ovary, whilst two cases of borderline mucinous neoplasms had concomitant Brenner tumours. The association of mucinous ovarian neoplasms and Brenner tumours is well documented.13,41 Wang et al. have shown a monoclonal origin of mucinous and Brenner tumours, suggesting that transitional epithelium of the Brenner tumour undergoes metaplastic reprogramming to mucinous epithelium, which proliferates to a mucinous tumour.42,43 This suggests that patients with benign Brenner tumours are at risk of developing MC and should be followed up.
Conservative surgical treatment of a borderline ovarian Brenner tumour in a pre-menopausal woman with subsequent pregnancy: case report of a rare entity
Published in Journal of Obstetrics and Gynaecology, 2020
Giulia Garofalo, Marie Chintinne, Dominique Thomas, Dario Bucella, Frederic Buxant
The histological analysis showed a cystic tumour lined with multi-layered epithelium resembling transitional cells. Within its walls, numerous clusters composed of transitional epithelium were scattered in a dense and fibrous stroma, some showing a cribriform architecture. They represented the benign Brenner component. The epithelial cells showed some low grade atypia and few mitoses. We did not observe any foci of invasion or high grade of atypia and the peritoneal cytology was benign. The ovary showed a large cystadenoma adjacent to the tumour, hence the definitive diagnosis was a borderline ovarian Brenner tumour associated to a cystadenoma (Figure 1).