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Consumer Views on Health Issues Arising from Food Products
Published in Megh R. Goyal, Preeti Birwal, Santosh K. Mishra, Phytochemicals and Medicinal Plants in Food Design, 2022
Harita R. Desai, Murlidhar Meghwal
As a means to prevent contamination in food catering outlets, the unit of the HACCP has been developed. An important function of the HACCP system is the identification and regulation of the varied steps involved in ensuring food product safety in a cost-effective manner. It mainly aims at controlling the food quality and safety based on a preventive approach [26]. There are seven steps in hazard identification and analysis, for example Conducting the hazard analysis.Identification of the CCP.Establishment of critical levels and limits.Establishment of a robust regulating system.Undertaking corrective measures.Verification of steps taken.Documentation.
Hazard Identification
Published in Samuel C. Morris, Cancer Risk Assessment, 2020
In addition to sources listed earlier, general references are often used to determine hazard (e.g., Sax, 1975; Clayton and Clayton, 1978). The National Research Council (e.g., NAS, 1972; 1980; 1981a; 1981b); and the World Health Organization (e.g., WHO, 1981) publish reviews of specific agents or groups of agents. Hazard analyses also may compare measured or estimated exposures to some standard: an environmental or occupational exposure standard (e.g., NIOSH/OSHA, 1978), for example, or may draw on existing epidemiological or toxicological literature and use findings for similar situations to make a first estimate of the potential hazard in a new situation. Some scientific and professional journals which have proved useful in this regard are listed in Table 3-11. Basically, any and all sources of information should be drawn upon for a hazard analysis.
Pharmacokinetic-Pharmacodynamic Modeling in Drug Development: Comments and Applications
Published in Hartmut Derendorf, Günther Hochhaus, Handbook of Pharmacokinetic/Pharmacodynamic Correlation, 2019
Joseph C. Fleishaker, James J. Ferry
A form of survival analysis was developed by Cox46 to describe, in a semiparametric manner, the hazard or risk of a certain event occurring by a certain time as a function of a baseline hazard and a relative risk term. This type of model has been used to model the risk of relapse during methotrexate maintenance in the treatment of acute lymphoblastic leukemia,47 and for the assessment of the risk of developing renal dysfunction during cyclosporine therapy.48 In these cases, the concentration ranges of the compounds of interest are treated as categorical data; the results of these analyses are seen in Figures 15 and 16. This method of analysis utilizes multivariate analysis and complex statistical models, but is useful for analyzing these types of data. The analyses are data-intensive, requiring large numbers of subjects and multiple determinations of clinical status for each subject. However, this method does take into account other covariates that may affect clinical outcome. In the case of methotrexate, covariates other than methotrexate which affected outcome included serum hemoglobin and white blood cell count.47 Hazard analysis is observational in nature; the results of these exploratory analyses need to be confirmed by further study.
The effect of educational intervention on promoting safe behaviors in textile workers
Published in International Journal of Occupational Safety and Ergonomics, 2022
Farideh Hatami, Rayhane Kakavand
Workers were randomly selected from three different shifts of the production line in the fields of spinning, weaving, weaving preparations and dyeing. To prevent bias in the results of this study, participants in each of the study groups were selected based on risk factors of worksites, literacy levels and age. In addition, the majority of participants in the study groups had an acceptable level of literacy. In this study, in order to identify the factors affecting safety behaviors based on the combination model while directly observing the intangible behavior of employees, three group discussion meetings were held with middle managers. The beginning of the discussion was a brief summary of the plan and the objectives were described. Furthermore, behavioral hazard analysis was used to identify risky behaviors and these risks can be determined using accident/incident reports, job hazards analysis, employee interviews and brainstorming. Thus, while identifying our 23 items, we categorized them under three categories of personal, environmental and organizational factors (Table 1).
Improved safety checklist analysis approach using intelligent video surveillance in the construction industry: a case study
Published in International Journal of Occupational Safety and Ergonomics, 2021
Shengyu Guo, Jichao Li, Kongzheng Liang, Bing Tang
Construction is one of the most dangerous industries [1]. According to the statistics of the Emergency Management Department of the People's Republic of China for the first half of 2018, there were 1732 accidents and 1752 fatalities in the construction industry, and the number of accidents in construction has been ranked first among industrial, mining and commercial accidents for 9 years [2]. Because of this serious situation, construction contractors have attempted to implement various safety measures to prevent occupational accidents, including safety training, site environment management, safety and health management, and appropriate health and safety plans [3]. The same approaches are adopted for safety assessment, such as job hazard analysis (JHA) [4], preliminary hazard analysis (PHA) [5], failure mode and effect analysis (FMEA) [6], fault tree analysis (FTA) [7], hazard and operability analysis (HAZOP) [8], and safety checklist analysis (SCA) [9].
Application of fuzzy fault tree analysis based on modified fuzzy AHP and fuzzy TOPSIS for fire and explosion in the process industry
Published in International Journal of Occupational Safety and Ergonomics, 2020
Mohammad Yazdi, Orhan Korhan, Sahand Daneshvar
In recent years, complex chemical plants have been developed rapidly to meet the increasing demands of the process industries [1]. As these plants usually make use of hazardous materials, their failure has the potential to cause serious harm, to both people and the environment [2]. For this reason, it is necessary to recognize the potential risks that are associated with the specified system and then take measures to minimize them. To deal with a large number of accidents, incidents, near misses and mishaps in the process industries, different risk assessment approaches have been developed and widely used to perform hazard analysis in order to enable the prevention of inadvertent incidents and plan for taking actions toward mitigating their effects [3]. According to Standard No. IEC 61025:2006 [4], fault tree analysis (FTA) is a well-known risk assessment technique with a logical diagrammatical method for evaluating the probability of an accident caused by series of faults and failure events.