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Reconstruction
Published in Karl H. Pang, Nadir I. Osman, James W.F. Catto, Christopher R. Chapple, Basic Urological Sciences, 2021
Nadir I. Osman, Karl H. Pang, Christopher R. Chapple
Ureterosigmoidostomy (~2.5%)Latency period of >20 years.Mixing of urine and faeces → carcinogenesis90% at anastomosis, 95% adenomatous.
Bladder Cancer
Published in Pat Price, Karol Sikora, Treatment of Cancer, 2020
Radical cystectomy involves en-bloc removal of bladder, prostate, and seminal vesicles in the male, or bladder, urethra, uterus, cervix, fallopian tubes, ovaries, and anterior vaginal wall in the female with surrounding perivesical fat, pelvic visceral peritoneum, and lymph nodes. Following cystectomy, the urine is most commonly diverted into an incontinent stoma via an ileal conduit, and formation of a uretero-ileal anastomosis. This is associated with a lower incidence of long-term metabolic disturbance and renal deterioration than its predecessor, the ureterosigmoidostomy. However, it is associated with significant physical and psychological morbidity and is therefore being superseded by continent diversions or orthotopic bladder substitutes.
The Large Bowel and the Anal Canal
Published in E. George Elias, CRC Handbook of Surgical Oncology, 2020
Although this procedure is less frequently performed today, patients who have had ureterosigmoidostomy have high incidence of developing adenomas and carcinoma near the site of the ureteral anastomosis. The latency period varies from 20 years in young patients such as teenagers, to 7 years in patients who are 60 years or older.
Causes of AA amyloidosis: a systematic review
Published in Amyloid, 2020
Anne Floor Brunger, Hans L. A. Nienhuis, Johan Bijzet, Bouke P. C. Hazenberg
Thirty-eight of the 60 diseases listed in Table 4 were reported only once. Schnitzler’s syndrome, ANCA-associated vasculitis and PCD are diseases that might be more strongly associated, but lack a second case with well-described histology. Although other unlikely associated diseases were described more often, descriptions were too vague or lacking (e.g. Leishmaniasis, SAPHO syndrome, myxoma, inflammatory pseudotumor and tumoral calcinosis). Inflammatory diseases such as septic arthritis and reactive arthritis were more likely to be related to underlying RA and TBC, or to spondyloarthropathy, obesity or inflammatory bowel disease, respectively. Pleura empyema and aneurysm were related to pre-existing bronchiectasis, endocarditis or TBC, and cases with myositis were related to underlying neoplastic disorders. In Sjögren’s syndrome, multiple myeloma and MGUS amyloidosis of AL type was more plausible. In patients on haemodialysis β2-microglobulin-associated (Aβ2M) amyloidosis and in the patient with multifocal motor neuropathy transthyretin-associated (ATTR) type amyloidosis were more plausible than AA amyloidosis. Finally, chronic lymphatic leukaemia and ureterosigmoidostomy were excluded from this review, since full-text papers could not be retrieved [55,56].
Treating potassium disturbances: kill the killers but avoid overkill
Published in Acta Clinica Belgica, 2019
R. Vanholder, W. Van Biesen, E. V. Nagler
Liddle’s syndrome is a rare autosomal dominant disease resulting in a hyperaldosteronism-like syndrome, combining excess tubular reabsorption of sodium and tubular potassium losses. Also excessive dietary sodium intake and polyuria (e.g. in polydipsia or osmotic diuresis) by enhancing urinary potassium losses [1], toluene inhalation (glue sniffing) and ureterosigmoidostomy may cause renal hypokalemia.