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Cortical Deafness (Plus Other Central Hearing Disorders)
Published in Alexander R. Toftness, Incredible Consequences of Brain Injury, 2023
Finally, amusia occurs when a person has difficulties with perceiving music, which can also affect a person's ability to produce music (Clark et al., 2015). It's sort of like tone deafness, but caused by brain damage. More specifically, there may be changes to a person's perception of timbre, loudness, pitch, and other musical traits (e.g., Terao et al., 2006). They may report that singing now sounds like shouting or that all musical notes now sound the same (Piccirilli et al., 2000).
Phosphoribosylpyrophosphate synthetase and its abnormalities
Published in William L. Nyhan, Georg F. Hoffmann, Aida I. Al-Aqeel, Bruce A. Barshop, Atlas of Inherited Metabolic Diseases, 2020
William L. Nyhan, Georg F. Hoffmann, Aida I. Al-Aqeel, Bruce A. Barshop
A small number of families have been reported [5, 6, 11, 12] in which deafness has been associated with an abnormally active PRPP synthetase. In one family, there were three involved males, each of whom also had severe neurodevelopmental impairment. The mother had high-tone deafness. A large kindred had previously been reported in which there were X-linked deafness and hyperuricemia; an enzyme defect was not demonstrated at the time of report [19].
Gynaecological cancer
Published in Peter Hoskin, Peter Ostler, Clinical Oncology, 2020
Cisplatin and paclitaxel can both cause neurotoxicity with peripheral neuropathy or less frequently spinal cord damage. Ototoxicity can result in tinnitus and high tone deafness. Reduced renal function is common but overt renal failure need not occur provided the patient is well hydrated and renal function is properly monitored.
Paediatric otitis media with effusion is connected to deficits in music perception
Published in Logopedics Phoniatrics Vocology, 2018
Anna Krzyżak, Olaf Zagólski, Michał Pawełek, Paweł Stręk
Perception of music in children aged 6.0–8.0 is assessed using the MBEMA, developed from the Montreal Battery of Evaluation of Amusia (MBEA) and validated for evaluation of music perception in children (11). The MBEA has been the most widely used tool for the evaluation of musical disorders in adults (12,13). It consists of six tests (180 test items) that use a common pool of 30 novel musical phrases consistent with Western tonality and of sufficient complexity to guarantee meaningful musical processing. The battery can be used to distinguish true amusics* (*individuals lacking normal musical abilities) from numerous cases of self-reported tone deafness with normal music processing abilities (14,15). In the MBEA version adapted for children (MBEMA), the length of the melodies is reduced compared to the test battery for adults (from average 10 notes to 7). Also the number of test items is reduced (from 30 to 20), and the metric test, which proves to be too difficult for 6-year-old listeners, is eliminated (11). In the present study, the MBEMA was performed for the detection of musical function impairment in all the participants. Ten different timbres (e.g. piano, marimba, guitar, flute, oboe, clarinet) were used to make the tests as engaging as possible. In the melodic organization tests (scale, contour and interval tests), three types of manipulations were applied to the same 10 melodies (Figure 1).
Online evaluation of congenital amusia (tone deafness) in paediatric stuttering individuals
Published in Hearing, Balance and Communication, 2019
Bünyamin Cildir, Özgül Akın Şenkal, Erdinç Aydın
Congenital amusia (commonly known as tone deafness); is considered as a genetically hereditary dysfunction which is related with anomalies in audial cortex and white and grey matter in ‘inferior frontal cortex’ [10]. It affects musical functions (mostly musical pitch) and can be found in 3 to 10% of the population [11]. Although congenital amusia is often considered as an independent anomaly and phenomenon, fundamentally it is related to numerous structures.