China
Africa
Explore chapters and articles related to this topic
Developmental Diseases of the Nervous System
Published in Philip B. Gorelick, Fernando D. Testai, Graeme J. Hankey, Joanna M. Wardlaw, Hankey's Clinical Neurology, 2020
James H. Tonsgard, Nikolas Mata-Machado
Disorders of primary neurulation: Myelomeningocele.Myeloschisis.Lipomas with dural defects (lipomyelomeningocele and lipomyeloschisis).
Paper 4
Published in Amanda Rabone, Benedict Thomson, Nicky Dineen, Vincent Helyar, Aidan Shaw, The Final FRCR, 2020
Amanda Rabone, Benedict Thomson, Nicky Dineen, Vincent Helyar, Aidan Shaw
Lipomyelomeningocele is a form of spina bifida. Although they do contain fat, it extends within the subcutaneous tissues and there are other important features such as neural arch defects. The bones in this case are normal.
Central Nervous System, Head and Neck
Published in Vincent Helyar, Aidan Shaw, The Final FRCR, 2017
This is a midline spinal bone defect with a skin covering (i.e. closed defect) in the lumbosacral region. There may be a dermal sinus, hairy patch or haemangioma above the intergluteal fold. May be incidental. Lipomyelocele—the lipoma/placode interface is inside the spinal canal.Lipomyelomeningocele—lipoma/placode interface is outside the spinal canal.
Congenital Spinal Lipomatous Malformations. Part 2. Differentiation from Selected Closed Spinal Malformations
Published in Fetal and Pediatric Pathology, 2021
Lumbosacrococcygeal spina bifida occulta develops as a skin-covered (closed) malformation from a combination of genetic, environmental, and perhaps other events that alter the primary or secondary neural tube and surrounding tissue in the embryo. Congenital spinal lipomatous malformations (spinal lipomas, lipomyeloceles, and lipomyelomeningoceles) in the midline of the lower back are relatively infrequently encountered whether they are isolated or, more commonly, part of a closed spina bifida complex. These malformations are the most common forms of closed spina bifida encountered in large clinical practices. Within this malformation group, there is no universally-recognized size distinction, subgroup definition, or histopathologic differentiation. The terms for these fibrofatty masses have been interchangeable. The terms themselves are minimally descriptive and only partially distinctive for site and cellular content. Some classifications require that a lipomyelomeningocele include spinal cord tissue outside the spinal canal; others do not. Meningeal tissue is usually not found [1].
Congenital Spinal Lipomatous Malformations. Part 1. Spinal Lipomas, Lipomyeloceles, and Lipomyelomeningoceles
Published in Fetal and Pediatric Pathology, 2020
Older terms such as occult spinal dysraphism and spina bifida occulta, often used for congenital spinal lipomatous malformations, provide no additional information to the clinician. Spinal lipoma, lipomyelocele, or lipomyelomeningocele may be the favored all-inclusive term for all congenital spinal lipomatous malformations by clinicians and pathologists, but more precise classification has been called for [4, 21], although unfortunately none has been suggested. Even when clinical distinctions within classifications are straightforward, clinical reports and pathology literature often disregard them [44]. These factors, along with the fact that under the microscope congenital spinal lipomatous malformations have little if any basis for subclassification, make the common names of spinal lipoma, lipomyelocele, and lipomyelomeningocele (as poorly distinguishable as they are in practice) the only terms generally recognized. Furthermore, congenital spinal lipomatous malformations are difficult to classify using terms providing both clinical and pathogenetic information [1, 68]. Clinical classification may rely on embryologic viewpoint, radiological imaging, and intraoperative observations in order to find dissection points and to carry out reconstruction. Pathologists generally follow developmental cues for terminology. Over time, embryologic and surgical viewpoints change [4, 31, 40]. Even arriving at a single, satisfactory group name has been elusive. A local decision on a single term such as spinal lipoma or lipomyelocele to cover the group or terms for denoting subtypes must be arrived at cooperatively.
Relationships among classifications of impairment and measures of ambulatory function for children with spina bifida
Published in Disability and Rehabilitation, 2021
Susan A. Rethlefsen, Melissa A. Bent, Nicole M. Mueske, Tishya A. L. Wren
Sixty-one children were included in the current study, 34 males (56%) and 27 females (44%). Average age of participants at enrollment was 9.8 years (standard deviation (SD) 2.7, range 6–15). Forty-seven participants (77%) had myelomeningocele and 14 participants (23%) had lipomyelomeningocele. Thirty-seven participants (61%) had ventriculoperitoneal shunts, 26/37 (70%) of whom had undergone at least 1 revision (range: 1–9 revisions). Sixteen participants (26%) had undergone prior tethered cord release surgery. Twenty-two participants (36%) had undergone previous orthopedic surgery to the lower limbs.