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Saussurea costus (Kust) and Senna alexandrina (Senna)
Published in Azamal Husen, Herbs, Shrubs, and Trees of Potential Medicinal Benefits, 2022
Amita Dubey, Soni Gupta, Mushfa Khatoon, Anil Kumar Gupta
Overdose causes griping abdominal pain and severe diarrhea, resulting in electrolyte loss. In vivo research suggests that side effects such as griping may arise from motility changes (Leng-Peschlow, 1980). Chronic use may lead to electrolyte imbalance disorders. Chronic use may result in hematuria, albuminuria, hypokalemia, metabolic alkalosis, and renal tubular damage and may cause Pseudomelanosis coli (pigmentation of the intestinal mucosa) (Leng-Peschlow, 1992c; Ramchander and Middha, 2017)
The patient with acute neurological problems
Published in Peate Ian, Dutton Helen, Acute Nursing Care, 2020
Hyponatraemia, hypernatraemia, hypocalcaemia, hypomagnesaemia and uraemia can all affect cerebral function. Hypo- and hypernatraemia are common causes of seizures. Hypocalcaemia and hypomagnesaemia can cause tingling of the hands and feet and in extreme cases, tetany. Hypocalcaemia can be identified by the Chvostek’s sign. This is a twitching of the facial muscles in response to tapping on the cheek (Mohebbi, Rosenkrans and Jung 2013). Please see Chapter 4 for further consequences of electrolyte imbalance.
Renal, Cardiovascular, and Pulmonary Functions of Dopamine
Published in Nira Ben-Jonathan, Dopamine, 2020
The kidneys play a critical role in keeping physiologically suitable electrolyte concentrations. This is done by filtering electrolytes and water from the blood, returning some to the blood and excreting any excess into the urine. Overall, the kidneys maintain a balance between the daily consumption and excretion of electrolytes and water. An electrolyte imbalance can result from dehydration or overhydration (e.g., intravenous fluid administration), effects of drugs, or certain heart, kidney, or liver disorders.
Peptide receptor radionuclide therapy in neuroendocrine neoplasms and related tumors: from fundamentals to personalization and the newer experimental approaches
Published in Expert Review of Precision Medicine and Drug Development, 2023
These are mainly related to the AA infusion used for renal protection (for details see PROCEDURE section of the chapter). Co-infusion of this AA raises a state of metabolic acidosis and causes symptoms like nausea, vomiting, abdominal discomfort, and headaches. Different centers have reported varying ranges of these effects (vomiting in 10%, significant nausea 25%) as a reporting system and threshold of the reference population. There also occurs a mild degree of electrolyte imbalance especially hyperkalemia and hypernatremia during this period [33]. Caution should be taken if there is severe nausea/vomiting precipitating a state of significant dehydration and thereby could further worsen the electrolyte imbalance. For all patients precautionary measures are taken using a combination of corticosteroid and antiemetic administration before PRRT. Some of these patients require repeat administration of this or consideration of drugs like aprepitant for symptom control. Adequate patient counseling, preparation, and hydration form the backbone of facing these effects.
Assessment of the dose-dependent biochemical and cytotoxicity of zein-coated MgO nanowires in male and female albino rats
Published in Annals of Medicine, 2021
Ghada H. Naguib, Gamal S. Abd El-Aziz, Hisham A. Mously, Sahar M. Bukhary, Mohamed T. Hamed
This study results showed that MgO-zein nanowires in the used doses did not affect the electrolytes levels compared to the control levels. In addition, both male and female rats have exhibited the same responses. Similar results previously reported that administration of various MgO preparations did not change serum potassium ion levels in healthy human volunteers [57]. It was reported that the electrolytes (electrolyte panel) contain many salts and minerals, like sodium, potassium, chloride, and bicarbonate, that are present in the blood and tissues [58]. They function to transfer electrical impulses across the body. Furthermore, electrolytes assist in transferring nutrients and cleaning the cells, preserve a normal water balance, and maintain normal pH [59]. Also, it was documented that any disease conditions that impact the quantity of fluid in the body like dehydration or influence the lung, kidney, metabolism, or breathing influence to induce fluid, electrolytes, or pH imbalance (acidosis or alkalosis). Electrolyte panels can be determined as important components of the basic metabolic panel. In addition, the determination of serum electrolyte concentration can aid to investigate if there is an electrolyte imbalance or not [14].
Clinical features of Chinese patients in different age groups with spontaneous intracerebral hemorrhage based on multicenter inpatient information
Published in Neurological Research, 2020
Pingping Wang, Yong Sun, Danhui Yi, Yanming Xie, Yumin Luo
This study showed the incidence of complications such as brain hernia, upper gastrointestinal bleeding, epilepsy was higher in younger patients. These complications were reported associated with ICH volume growth and poor outcome [22,23]. Clinically, this population should be dynamically monitored for intracranial pressure, imaging examination, clinical signs and analyzed in a timely manner to provide effective interventions for the reduction in the incidence of hernias and other malignant complications. Pulmonary infection, urinary tract infections, electrolyte metabolism disorders and pressure injury were more common in older patients. Therefore, attention should be paid to the clinical care of the respiratory tract, urinary tract, skin and electrolyte conditions of elderly patients. The application of drugs, such as dehydration drugs and antihypertensive drugs, that easily lead to electrolyte imbalance should be carefully used and dynamically monitored in these patients.