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Fever in Diseases of the Cardiovascular System
Published in Benedict Isaac, Serge Kernbaum, Michael Burke, Unexplained Fever, 2019
The clinical picture includes fever, arthralgia, or polyarthritis, tachycardia, disproportionate to the degree of fever and persisting during sleep, murmurs, conduction disturbances and cardiac failure. Additional “major” manifestations, viz., chorea, erythema marginatum, and subcutaneous nodules, are exceedingly rare. Some patients will present as a FUO,76,77 although most cases will have migratory polyarthritis as well. Any joint may be involved, the larger lower limbs joints being affected most frequently. Arthritis tends to be of longer duration and more severe in the adult.76 Carditis usually occurs within the first 3 weeks of the attack and is virtually always manifested by a regurgitant murmur (mitral and/or aortic) and frequently by an apical middiastolic (Carey—Coombs) murmur. Pericardial friction rub and signs of cardiac failure may also be present. Carditis is most frequent in the younger age group and is less common in adults.
Pericardial disease in the elderly
Published in Wilbert S. Aronow, Jerome L. Fleg, Michael W. Rich, Tresch and Aronow’s Cardiovascular Disease in the Elderly, 2019
A pericardial friction rub is usually a high-pitched, scratchy, or squeaky sound heard best at the left lower sternal border; it is thought to be generated by friction of the two inflamed layers of the pericardium, corresponding to the movement of the heart within the pericardial sac (8,9). The rub can be transient, mono-, bi-, or triphasic and variable in intensity. An audible friction rub is highly specific for pericarditis. It is rarely reported and require careful and repeated cardiac auscultation (1–4).
Pericardial disease
Published in Swati Gupta, Alexandra Marsh, David Dunleavy, Kevin Channer, Cardiology and the Cardiovascular System on the move, 2015
Swati Gupta, Alexandra Marsh, David Dunleavy, Kevin Channer
SignsPyrexiaTachypnoeaTachycardiaPericardial friction rub
Postpericardiotomy syndrome after cardiac surgery
Published in Annals of Medicine, 2020
Joonas Lehto, Tuomas Kiviniemi
The prevalence of typical symptoms and clinical findings are detailed in Table 1. The most characteristic symptom of PPS is pleuritic or pericarditic chest pain, referring to a stabbing pain often radiating to precordial region, neck, back, shoulders, arms, lower chest, and abdomen, made worse by coughing, deep breathing, swallowing, or any movement, and in severe cases leading to a fast and shallow respiration easily confused with the dyspnoea of congestive heart failure [23,26,46,48–50]. The reported incidences of the symptom have varied largely, but according to a recent prospective study, pleuritic chest pain occurs in over a half of the PPS episodes [5]. An intermittent, low grade fever is another common feature of PPS, and it occurs in approximately a half of the PPS cases [5,12,43]. The fever is usually the first manifestation. It may merge with the early postoperative temperature elevations so that the patient has a prolonged febrile course, but more often the fever recurs as a delayed reaction after a distinct afebrile period [55]. Another characteristic clinical finding is pericardial friction rub detected in the heart auscultation. The reported incidences of the friction rub have varied tremendously. According to recent studies it is detected in 20 to 30% of patients [5,47], although it has been suggested that it could probably be heard at some time in all patients but due to the transient nature a serial auscultation strategy is necessary [55]. The start of medical treatment, especially corticosteroids, offers a prompt relief of symptoms, typically within 24 to 48 h [10].
Incidence and Causes of 30-day Readmissions after Surgical Versus Percutaneous Secundum Atrial Septal Defect Closure: A United States Nationwide Analysis
Published in Structural Heart, 2019
Mohammad K. Mojadidi, Ahmed N. Mahmoud, Dhruv Mahtta, Muhammad O. Zaman, Islam Y. Elgendy, Akram Y. Elgendy, Nayan Agarwal, Nimesh K. Patel, Zachary M. Gertz, Siddharth A. Wayangankar, David C. Lew, Hani Jneid, Creighton W. Don, Bernhard Meier, Jonathan M. Tobis
Post-pericardiotomy syndrome was the most common cause of hospital readmissions following surgical ASD closure. This syndrome which is often propagated by an amplified immune response, occurs 1–6 weeks after a cardiac surgery requiring pericardial incision. Fever, pleuritic chest pain, new or worsening pleural or pericardial effusion, or pericardial friction rub are some of the most common clinical findings associated with this condition.28 The incidence of this syndrome has been reported in 10–50% of cardiac surgeries.29,30 The 30-day follow-up period for hospital readmissions coincides directly with the period when patients undergoing surgical ASD closure are at high risk for developing this syndrome due to a surge in the immune response. The second most common cause of readmissions (in both surgical and percutaneous groups) was heart failure. Among other indications, ASD closure is recommended in patients with right ventricle volume overload due to shunt physiology or underlying pulmonary artery hypertension. Such patients are at high risk for heart failure exacerbations and hence, a large proportion of readmissions seen in this study may be attributed to this etiology.
Usefulness of neutrophil-to-lymphocyte ratio for predicting acute pericarditis outcomes
Published in Acta Cardiologica, 2022
Fatih Yılmaz, Filiz Kizilirmak Yılmaz, Ali Karagöz, Arzu Yıldırım, Haci Murat Gunes, Ravza Betül Akbas, Süleyman Çağan Efe, İrfan Barutçu
The presence of pericardial friction rub was also found to be a negative predictor in these patients. This may be related to the absence of pericardial friction rub in patients with moderate and extensive effusion, and more recurrence may be seen in these patients due to the more intense inflammatory response.