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Monographs of essential oils that have caused contact allergy / allergic contact dermatitis
Published in Anton C. de Groot, Monographs in Contact Allergy, 2021
Rosmarinus officinalis L. is a woody evergreen perennial herb, up to 1.5 meter tall, which has strongly aromatic, needle-like evergreen leaves. Rosemary is native to the Madeira Islands, the Canary Islands, northern Africa, the Mediterranean European countries, Cyprus, Turkey, and the Caucasus (GRIN Taxonomy for Plants). The plant is widely cultivated for medicinal, culinary, cosmetic and ornamental purposes. Rosemary is one of the most prized culinary herbs, especially in Mediterranean cuisine (6). R. officinalis has also been extensively used in traditional folk medicine.
Ethnopharmacology of Wild Plants Used in Diabetes
Published in Mahendra Rai, Shandesh Bhattarai, Chistiane M. Feitosa, Ethnopharmacology of Wild Plants, 2021
Patricia Landazuri, Nelsy Loango Chamorro, Beatriz Restrepo Cortes
R. officinalis is an aromatic evergreen herb shrub that is widely distributed in the Mediterranean region, but now this plant is cultivated and used worldwide. Parts used: leaves and stems, compounds: phenolic abietane diterpenes as carnosic acid; flavonoids, carnosol, caffeic acid, rosmarinic, alfa-pinene, camphor, eucalyptol, chlorogenic acid, monomeric acid, oleanolic acid, ursolic acid, rosmadial, rosmanol, rosmaquinones A and B, secohinokio, and derivatives of eugenol and luteolin (Cui et al. 2012, Ribeiro-Santos et al. 2015, Sedighi et al. 2015, Sánchez-Camargo and Herrero 2017, Oliveira et al. 2019).
Herbal Product Development and Characteristics
Published in Anil K. Sharma, Raj K. Keservani, Surya Prakash Gautam, Herbal Product Development, 2020
Mirian Pateiro, Rubén Domínguez, Predrag Putnik, Danijela Bursać Kovačević, Francisco J. Barba, Paulo S. E. Munekata, Elena Movilla Fierro, José M. Lorenzo
Sage as medicinal plant has antimicrobial, antioxidative, antimalarial, anti-inflammatory, antidepressant, antidiabetic, cardiovascular, and anti-tumor effects (Shakeri et al., 2016; Uritu et al., 2018). Salvia glutinosa L., Salvia lavandulifolia L., Salvia officinalis L., and Salvia verticillata L., are important species included in this genus. S. lavandulifolia L. and S. officinalis L. were the most common members of these genera, and the last one is the most valuable, due to the large amount of detected BAC (Pop et al., 2014). The use of S. officinalis L. is regulated by the FDA (FDA, 2018).
Self-treatment attempt of tobacco use disorder with Melissa officinalis: a case report and brief review of literature
Published in Journal of Addictive Diseases, 2023
Baris Sancak, Gizem Dokuzlu, Ozan Özcan, Urun Ozer Agirbas
As in this case, it can be discussed how a herbal product consumed via an inhaled pathway may have a place in current treatment approaches. M. Officinalis has been reported as a sedative, which has healing properties on stress, anxiety, and sleep problems.11 Due to these effects, it can be considered beneficial for some mental symptoms caused by nicotine withdrawal. Studies indicate that the psychological effects of M. officinalis are related to the specific mechanisms of essential oils in its content. The first of these mechanisms is inhibition of gamma-aminobutyric acid transaminase (GABA-T) activity through essential oils such as rosmarinic acid, and the triterpenoids oleanolic acid and ursolic acid. Inhibition of GABA-T increases the GABA levels in the brain which causes the anti-anxiety activity of M. Officinalis.12 This effect has been studied in more detail in animal models. In a study, elevated plus maze and open field test results of mice given Melissa extract at different doses (120, 240, and 360 mg/kg) for 15 days were evaluated. Compared to the open field test, which increased the plasma corticosteroid level more, it was observed that there was a more significant anti-anxiety activity in the elevated plus maze test. This suggests that Melissa may be beneficial in low-to-moderate anxiety, but its effect may not be sufficient in severe anxiety. Also, no significant outcome was found at the low dose (120 mg/kg), while a significant benefit was seen at higher doses.13
Natural inhibitors for acetylcholinesterase and autophagy modulators as effective antagonists for tau and β-amyloid in Alzheimer’s rat model
Published in Biomarkers, 2023
Mervat Hassan, Hisham Ismail, Olfat Hammam, Abdullrahman Elsayed, Othman Othman, Sohair Aly Hassan
A dose selection of R. Officinalis L. or C. sativus L. was carried out based on the drug tolerance study and according to OECD criteria (The Organisation for Economic Co-operation and Development [OECD] 2000). Animals were divided into 9 groups (Six rats each), All groups received single oral dosage (1 mL) of Saffron and rosemary extracts at concentrations 250, 500, 750, and 1000 mg/kg body weight except the normal group (Six rats each) which was injected orally with Saline (0.9%). Six hours after receiving the curative injection, the rats were examined for toxicity, and death was noted every 24 hours for 15 days. During the follow-up period, no mortality was noted at the 250 mg/kg or 500 mg/kg doses. So, in this study, the 500 mg/kg dose was utilised for further investigations.
Protective effect of valerian extract capsule (VEC) on ethanol- and indomethacin-induced gastric mucosa injury and ameliorative effect of VEC on gastrointestinal motility disorder
Published in Pharmaceutical Biology, 2022
Yuan Feng, Wan Dai, Junyu Ke, Yong Cui, Shuang Li, Jingjing Ma, Wenfeng Guo, Gang Chen, Ning Li, Yanwu Li
Available antiulcer drugs and motility-modifying drugs, chemical drugs are common but have various side effects. Thus, it is necessary to develop novel drugs that are safer, effective, and readily accessible in the treatment of gastric ulcers and GI motility disorder. Valeriana officinalis L. (Caprifoliaceae), also called valerian, native to Europe and Asia, is commonly used as a medicinal plant to treat anxiety, sleep disorder, depression, and GI hyperactivity (Houghton 1999; Poyares et al. 2002; Muller et al. 2003; Taavoni et al. 2011; Mineo et al. 2017; Tammadon et al. 2021). Prior work indicates that the extract of V. officinalis has antioxidant and antispasmodic effects (Malva et al. 2004; Circosta et al. 2007; Sudati et al. 2009). However, most existing research results associated with valerian are related to insomnia, few investigations about valerian or its extracts in treating gastric mucosa damage were reported.