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Asparagus Sp.: Phytochemicals and Marketed Herbal Formulations
Published in Amit Baran Sharangi, K. V. Peter, Medicinal Plants, 2023
Vikas Bajpai, Pratibha Singh, Preeti Chandra, Brijesh Kumar
Selected Asparagus species A. racemosus, A. officinalis, A. adscendens s is used in Ayurveda for prevention and treatment of dyspepsia, gastric ulcers, inflammation, liver diseases and in infectious disease and nervous disorders. Traditionally, these plants occupy an important position in the socio-cultural, spiritual, and medicinal arena. It has anti-bacterial, antimicrobial, and immune-modulatory properties and as digestive tonic for diarrhea, dysentery, dyspepsia, and indigestion. These plants are used in the treatment of several skin diseases and hence are the best herb used in Ayurvedic medicine for the treatment of women’s fertility issues like in the treatment of infertility, loss of libido, stomach ulcer, hyperacidity, vulnerable miscarriage, menopausal problems, and bronchial infection. The plants are also used in the cure of rheumatism, diabetes, and brain complaints. It is used in the management of behavioral disorder and minimal brain dysfunction. The rhizome of several Asparagus plants is used as a soothing tonic that acts mainly on the circulatory, digestive, respiratory, and female reproductive organs. The root is alterative, antispasmodic, aphrodisiac, demulcent, diuretic, and refrigerants (Hasan et al., 2016). Many plants of Asparagus species are commercially important plants and produced as food yielding crops, and used in agricultural and as horticultural plants and is a good companion plant for tomatoes, parsley, and basil, as well as it is used in preparation of herbal medicine.
Common Medicines from Herbs, Minerals and Animal Sources
Published in Mehwish Iqbal, Complementary and Alternative Medicinal Approaches for Enhancing Immunity, 2023
One of the most famous adaptogens, Asparagus racemosus, is categorised as Rasayana, a herb that improves vigour, vitality and immunity (Govindarajan et al., 2005; Rege et al., 1999). A part of the family Asparagaceae, previously Asparagus racemosus, has been revealed to stimulate antioxidant, antibacterial, antitussive, immunomodulatory and antihepatotoxic effects in both human and rodent models (Alok et al., 2013). The therapeutic usage of the shatavari plant has been documented in British and Indian pharmacopoeias and traditional medicinal systems. The word shatavari factually means ‘capable of possessing [a] hundred husbands' and capacity to provide strength to reproductive health so that females can give rise to healthy ova. Asparagus has also been consumed to enhance fertility and vitality. In the traditional medicinal system, shatavari has been perceived as one of the most significant herbs, typically advised for providing nourishment to ovaries, maintaining sexual desire in women and enhancing the synthesis of reproductive hormones (Pandey et al., 2018).
Nutrition Part II
Published in Mark C Houston, The Truth About Heart Disease, 2023
Add the asparagus, lemon slices, olive oil, freshly squeezed lemon juice, sea salt, ground black pepper, minced garlic, to the baking sheet. Toss to evenly coat. Place in the oven and roast for eight to ten minutes or until the asparagus is crisp on the outside and tender in the center.
Evaluation of immunological adjuvant activities of saponin rich fraction from the fruits of Asparagus adscendens Roxb. with less adverse reactions
Published in Drug and Chemical Toxicology, 2023
Rahul Singh, Rinku Sharma, Rajat Varshney, Gorakh Mal, Mayukh Ghosh, Birbal Singh
Asparagus adscendens Roxb. (AA) (family: Asparagaceae) commonly known as ‘Shatavari’ is frequently found in India and Pakistan (Mannan et al. 2015). It consists of triterpenoids, saponins, steroids, aliphatic, nitrogenous, and phenolic compounds. Asparagus genus has been attributed to have various pharmacological properties including anti-inflammatory, antitussive, antimicrobial, immunomodulatory, hepatoprotective, antistress, and antiulcer activities (Singh and Geetanjali 2016). However, so far there is no published information available about the safe use of SRF extracted from the fruits of Asparagus adscendens Roxb. (AA-SRF) as a potential adjuvant. Therefore, in vitro hemolytic and cytotoxicity, in vivo toxicity and adjuvant potential of the AA-SRF in Swiss albino mice have been evaluated for the first time in the present study.
An Overview of Hepatocellular Carcinoma with Emphasis on Dietary Products and Herbal Remedies
Published in Nutrition and Cancer, 2022
Deepa S. Mandlik, Satish K. Mandlik
Asparagus (Asparagus officinalis L.) is a common vegetable that can be utilized in a variety of dishes, soups and salads. A. officinalis has been linked to a variety of pharmacological activities, including anti-mutagenicity, anti-inflammation and cytotoxicity, according to several reports. The key constituents responsible for the plant’s bioactivities were proposed to be steroidal saponins, polysaccharides and flavonoids obtained from the plant. Asparagus polysaccharide has been used in the treatment of cancers such as leukemia, breast cancer and lung cancer in clinical trials. According to a review, the asparagus polysaccharide inhibited cell proliferation in HepG2 and Hep3B cells with less toxicity than regular human hepatocellular 7702 cells. The induction of G2/M phase arrest and apoptosis by asparagus polysaccharide through modulation of Bax, Bcl-2, and caspase-3 contributed to the results, according to a mechanistic analysis (58). In a rat model, combining asparagus polysaccharide with transcatheter arterial chemoembolization inhibited the progress of liver tumor and extended survival time while causing minimal toxicity (59). Many cancers, including gastric cancer, oesophagal cancer, leukemia and lung cancer are resistant to Asparanin A (steroidal saponin) obtained from A. officinalis (60). Aasparanin A inhibited HepG2 cells in a dose-dependent manner. Cdk1, Cdk4, and cyclin A were all downregulated, while p21WAF1/Cip1 was upregulated, resulting in G2/M cell cycle arrest. Furthermore, Asparanin A treatment of HepG2 cells promoted apoptosis via both the intrinsic and extrinsic pathways (61).