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Neurologic Diagnosis
Published in Philip B. Gorelick, Fernando D. Testai, Graeme J. Hankey, Joanna M. Wardlaw, Hankey's Clinical Neurology, 2020
Myokymia is the phenomenon of regularly recurring brief bursts of rapidly firing MUPs at relatively constant intervals (0.1–10 Hz). It manifests clinically as persistent spontaneous rippling and quivering of muscles at rest. It is a nonspecific finding, often associated with radiation nerve damage, and it is commonly benign in eyelid muscles.
General Practice
Published in Keith Hopcroft, Instant Wisdom for GPs, 2017
Myokymia is an utterly harmless fasciculation of muscles around the eye. It is very common in the general population but only rarely presented to the GP – and then usually in a patient who is concerned that it is a harbinger of neurological doom. So, usually, reassurance is all that is required.
Fifi
Published in Walter J. Hendelman, Peter Humphreys, Christopher R. Skinner, The Integrated Nervous System, 2017
Walter J. Hendelman, Peter Humphreys, Christopher R. Skinner
The common exception is myokymia, a typically transient phenomenon in which there are irregular, focal muscle twitches that appear to derive from irritability in the motor axons that control the twitching region. A typical example is eyelid myokymia, the intermittent twitching of one eyelid that may develop when one is overtired or has consumed too many caffeinated beverages.
Swallow-Induced Eyelid Myokymia: A Novel Synkinesis Syndrome
Published in Neuro-Ophthalmology, 2020
Amrita-Amanda D. Vuppala, Gregory J. Griepentrog, Ryan D. Walsh
Myokymia is a disorder of involuntary, fine, undulating, non-synchronous striated muscle fibre contractions resulting in a visible rippling of the overlying skin.1 Eyelid myokymia is the most common type of focal facial myokymia and involves the orbicularis oculi muscle.2 Clinically, eyelid myokymia is typically described by patients as small annoying twitches of the upper or lower eyelids.3 It may be triggered by fatigue, stress, excessive caffeine, or physical exertion and is most often a benign and self-limited condition.2 Other reported aetiologies include topiramate,4-6 autoimmune diseases,7,8 multiple sclerosis,1,9–11 brainstem pathology (such as pontine glioma),12 and repetitive sessions of anodal transcranial direct current stimulation.13 In this report, we describe a novel case of eyelid myokymia triggered by swallowing.
Eyelid Myokymia with Concomitant Cerebral Tumour: A Case Report
Published in Neuro-Ophthalmology, 2018
Yoshiyuki Kitaguchi, Maria Suzanne Sabundayo, Hirohiko Kakizaki
There were several atypical features of eyelid myokymia in the present case. The symptoms were present in the upper eyelid, in addition to the lower eyelid, which is typically involved in this entity.2–4 The symptoms continued for 6 months, whereas eyelid myokymia is usually self-limiting. The subjective experience of a lateral pulling sensation was the other atypical feature in the current case.2 These features motivated us to take an MRI to search for a possible intracranial lesion causing hemifacial spasm and eyelid myoclonus,10 although a tonic or a jerking movement was not apparent on physical examination.
Ocular Neuromyotonia: Case Reports and Literature Review
Published in Strabismus, 2018
Anne-Catherine Stockman, Maria Dieltiëns, Hilde Janssens, Maria Van Lammeren, Liesbet Beelen, Veerle Van Bellinghen, Catherine Cassiman
Peripheral neuromyotonia, also known as Isaacs syndrome and not limited to ONM, is a state of involuntary sustained muscle hyperactivity, which can be triggered by a voluntary muscle contraction. This is due to abnormal excitability of peripheral motor nerve axons of the affected muscle. The clinical presentation varies, as well as the associated electrophysiological abnormalities. Patients may present with myokymia, fasciculations, muscle cramps, stiffness, fatigue, and other related symptoms.