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Cosmetic-Medical Treatments
Published in Paloma Tejero, Hernán Pinto, Aesthetic Treatments for the Oncology Patient, 2020
M. Lourdes Mourelle, B. N. Díaz
Silver foam dressing, used in the treatment of burns and ulcers, has been shown to resist wound bacteria, promote wound healing, and shorten recovery time, effectively relieving the pain of patients [70,71]. When used in oncology, it has also been demonstrated as effective in reducing radiation dermatitis, apparently because of its antibacterial properties [72]. Nevertheless, another study by Aquino-Parsons concluded that silver leaf nylon dressing use did not demonstrate a decrease in the incidence of inframammary moist desquamation but did decrease itching in the last week of radiation and 1 week after treatment completion [73].
Wounds, healing and tissue repair
Published in Professor Sir Norman Williams, Professor P. Ronan O’Connell, Professor Andrew W. McCaskie, Bailey & Love's Short Practice of Surgery, 2018
Professor Sir Norman Williams, Professor P. Ronan O’Connell, Professor Andrew W. McCaskie
This is now more correctly known as negative pressure wound closure. Applying intermittent negative pressure of approximately -125 mmHg appears to hasten debridement and the formation of granulation tissue in chronic wounds and ulcers. A foam dressing is cut to size to fit the wound. A perforated wound drain is placed over the foam, and the wound is sealed with a transparent adhesive film. A vacuum is then applied to the drain (Figure3.10). Negative pressure may act by decreasing oedema, by removing interstitial fluid and by increasing blood flow. As a result, bacterial counts decrease and cell proliferation increases, thereby creating a suitable bed for graft or flap cover.
Reconstructive surgery – Harvesting, skin mucosa, bone, cartilage
Published in John Dudley Langdon, Mohan Francis Patel, Robert Andrew Ord, Peter Brennan, Operative Oral and Maxillofacial Surgery, 2017
Once the skin graft is secured in place, either by fine resorbable sutures such as 5/0 Vicryl, while some advocate cyanoacrylate glue, dressings should be firmly placed over the graft to oppose it to the wound bed. Silicone mesh covered by proflavine-soaked cotton-wool dressing or a foam dressing all secured by tie over sutures or staples are ideal.
Therapeutic advances in wound healing
Published in Journal of Dermatological Treatment, 2022
André Oliveira, Sandra Simões, Andreia Ascenso, Catarina Pinto Reis
Although NPWT has been demonstrated to be effective in the treatment of numerous wounds as previously mentioned, there are some potential complications associated with its use. Therefore, clinicians should be aware of strategies to prevent them. There are three major complications, which can potentially be life-threatening, such as bleeding, infection, and retention of the foam dressing (147,149). The primary cause of bleeding is the mechanical damage of the underlying tissues and can be aggravated by infection, necrotic tissue or coagulopathy (149). Thereupon, it is not recommended NPWT’s foam dressing to be in direct contact with exposed blood vessels, organ, nerves, or anastomotic sites since the risk of fistulae formation in the presence of exposed organ or hemorrhage with exposed blood vessels is increased (147). Regarding the infections, the relation between infection and application of NPWT is not clearly defined although some authors have described chronic wound sepsis caused by retention of the foam dressing (150). Infections should be treated before NPWT application (147). Finally, retention of the foam in the wound may cause infection or bleeding since the dressing materials used with NPWT do not dissolve, and therefore, provoke an inflammatory reaction slowing the wound healing process down. Other complications include pain associated with dressing changes and patient’s allergy to the adhesive dressing or the foam material (in these cases, NPWT is not recommended) (147).
Negative pressure wound therapy: device design, indications, and the evidence supporting its use
Published in Expert Review of Medical Devices, 2021
Stephen J. Poteet, Steven A. Schulz, Stephen P. Povoski, Albert H. Chao
The concept of applying negative pressure to open wounds has existed since antiquity. Christine Miller provides a fascinating account of the historical evolution of negative pressure which began during ancient times when Roman medical personnel applied direct mouth suction to remove poison or infected fluid from wounded soldiers in battle[1]. This technique persisted into the 19th century until a British physician named Dr. Francis Cox developed the ‘glass leech’ suction apparatus using a wide neck cupping device. This modification was later followed by Dr. Gustav Bier who developed a similar cupping system with the addition of tubing and a bulb to remove wound exudate[1]. In 1986, Dr. Nail Bagautdinov in Russia described using a plain polyethylene film over open wounds which was secured to the surrounding skin with petrolatum and attached to a vacuum pump, a construct similar to modern designs. Another similar system using a polyvinyl foam dressing to treat open fracture wounds was developed in Germany and published in 1993 by Fleischmann et al [2].
Bart’s Syndrome with Novel Frameshift Mutations in the COL7A1 Gene
Published in Fetal and Pediatric Pathology, 2019
Young Mi Han, Narae Lee, Shin Yun Byun, Sang-Jin Cheon, Hyun-Chang Ko
Although the patient had difficulty sucking owing to lesions in the oral cavity, she could be fed with a bottle. The bullous lesions gradually spread to the abdomen and back and were accompanied by bleeding. The lesions intermittently improved and worsened (Figure 5a–c). The patient required electrolyte and anemia correction for complications involving hyponatremia with a serum Na+ level of 121 mmol/L and thrombocytosis with a platelet count of 1225 × 103/μL 2 weeks after birth and anemia with a hemoglobin level of 7.9 g/dL and hypoalbuminemia with an albumin level of 2.0 g/dL 3 weeks after birth. Seven weeks after birth, methicillin-resistant Staphylococcus aureus (MRSA) was isolated from her skin and blood cultures. Accordingly, the patient underwent systemic vancomycin treatment for MRSA sepsis for 2 weeks. We managed the patient with a daily dressing with foam dressing material with topical fusidic acid and dexpanthenol cream. The blisters later formed milia and improved. The platelet count started to decrease 6 weeks after birth to a count of 861 × 103/uL and gradually reached the normal range. She was discharged 103 days after birth after skin epithelialization was observed and normal electrolyte levels and thyroid function were maintained. The patient is currently 11 months old and has been followed up in the department of dermatology and pediatrics. The bullous lesions have been alternately improving and worsening; nevertheless, the patient has been maintaining normal thyroid function with the aid of pharmacotherapy.