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DRCOG MCQs for Circuit A Questions
Published in Una F. Coales, DRCOG: Practice MCQs and OSCEs: How to Pass First Time three Complete MCQ Practice Exams (180 MCQs) Three Complete OSCE Practice Papers (60 Questions) Detailed Answers and Tips, 2020
Congenital hip dislocation: More common in females than in males.Can be detected at birth.Often painful.Will result in a palpable 'clunk' (Ortolani's sign) when the hips are slowly abducted from a 90° flexed position.May be associated with breech presentation.
Congenital and Developmental Abnormalities
Published in Harry Griffiths, Musculoskeletal Radiology, 2008
This used to be known as congenital hip dislocation or congenital dysplastic hip. Most babies, just after their birth, have an Ortolani test, which is performed to check infants for hip dislocation. In a normal neonate, no sound is elicited by this procedure; however, in children with developmental hip dysplasia (DHD), there is often a click. If it is necessary to confirm this, ultrasound is probably the best way to do so (10). However, X rays can be very useful, particularly in the later stages of the condition, once the femoral head is ossified.
14-year hip survivorship after periacetabular osteotomy: a follow-up study on 1,385 hips
Published in Acta Orthopaedica, 2020
Josefine Beck Larsen, Inger Mechlenburg, Stig Storgaard Jakobsen, Theis Munchholm Thilleman, Kjeld Søballe
Patients were identified from our institutional database on patients undergoing PAO. 1,721 surgically treated hips between January 2004 and December 2017 were eligible for inclusion in this study (Figure 1). The vast majority of operations were performed by the senior author (KS); the rest were performed (parts of or entirely) by 4 surgical fellows, thus minimizing the surgical learning curve. Concomitant hip arthroscopy is not performed at our institution. The exclusion criteria were reverse PAO, femur osteotomy, persons without a Danish civil registration number (patients from abroad), Legg–Calvé–Perthes disease, and congenital hip dislocation. 1,385 hips (1,126 patients) met the inclusion criteria. During the study 3 patients died unrelated to the operation (4 hips) and 11 patients emigrated (13 hips).
Reduced length of uninterrupted institutional stay after implementing a fast-track protocol for primary total hip replacement
Published in Acta Orthopaedica, 2018
Konsta J Pamilo, Paulus Torkki, Mikko Peltola, Maija Pesola, Ville Remes, Juha Paloneva
THRs performed for secondary OA, and revisions were excluded (Appendix 1, see Supplementary data). A diagnosis of secondary hip OA was noted retrospectively from the beginning of 1987. A patient was excluded from the study if a diagnosis of secondary hip OA had been recorded in the Hospital Discharge Register between the beginning of 1987 and the day of the operation. Patients with a diagnosis of congenital hip dislocation (Q65.0–Q65.9) were excluded. Patients listed in the Social Insurance Institution database as eligible for reimbursement for the sequelae of transplantation, uremia requiring dialysis, rheumatoid arthritis, or connective tissue disease were excluded from the study. We also excluded patients who were not Finnish citizens or were residents of the autonomous region of Åland.
Lack of association between COL1A1 and COL9A2 single nucleotide polymorphisms and intervertebral disc degeneration
Published in British Journal of Neurosurgery, 2021
Sara Hanaei, Sina Abdollahzade, Maryam Sadr, Ehsan Fattahi, Mohammad Hossein Mirbolouk, Alireza Khoshnevisan, Nima Rezaei
The α1 subunit of collagen type I (COL1A1) is located at chromosome 17q21.33.11 As the high importance of this type collagen in the ECM, the association of its SNPs has been widely investigated in different ethnicities. The genetic polymorphisms in collagen type I lead to abnormal expression of α1 and α2 subunits which finally resulted in dys-structured collagen type I due to disproportional expression of its subunits.17 However, while the role of some polymorphisms was quite significant, the others had less determinative role in IVDD. One of these SNPs which was of interest in many investigations is COL1A1 Sp1 (rs1800012) which is in intron 1 of the respective gene.14 This G/T polymorphism mainly resulted in bone homeostasis imbalance leading to its low density, high turnover, high fracture risk and osteoporosis. Based on genetic investigation in Netherlands, Greece, and Turkey on IVDD patients, the homozygote ‘TT’ genotype was remarkably associated with both severity18,19 and high susceptibility to IVDDcompared to ‘GG’ genotype.11,18 The COL1A1 rs909102 was detected concomitant with decreased signal intensity of lower lumbar discs, however, this association was not significant.13 As found in the current study, neither COL1A1 rs909102 nor other SNPs of this gene were significantly associated with congenital hip dislocation.15 On the other hand, a meta-analysis results revealed that although the SNP of interest in the current study was not in association with otosclerosis in Belgian-Dutch population, the role of rs2141279 was remarkable.14